Results 1 to 10 of about 5,770,101 (353)
Advanced Science, 2023 Cancer immunotherapies have improved human health, and one among the important technologies for cancer immunotherapy is cancer vaccine. Antigens are the most important components in cancer vaccines.
Lu Diao, Mi Liu
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Cancer vaccines: current status and future directions. [PDF]
J Hematol OncolCancer continues to be a major global health burden, with high morbidity and mortality. Building on the success of immune checkpoint inhibitors and adoptive cellular therapy, cancer vaccines have garnered significant interest, but their clinical success ...
Zhou Y, Wei Y, Tian X, Wei X.
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Cancer vaccines: platforms and current progress. [PDF]
Mol BiomedCancer vaccines, crucial in the immunotherapeutic landscape, are bifurcated into preventive and therapeutic types, both integral to combating oncogenesis.
Lei W, Zhou K, Lei Y, Li Q, Zhu H.
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Cancer Cell, 2022 Given the renewed interest in vaccine development sparked by the COVID-19 pandemic, we are revisiting the current state of vaccine development for cancer prevention and treatment. Experts discuss different vaccine types, their antigens and modes of action, and where we stand on their clinical development, plus the challenges we need to overcome for ...
Schiller, John T +13 more
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Development of a VRC01-class germline targeting immunogen derived from anti-idiotypic antibodies
Cell Reports, 2021 Summary: An effective HIV-1 vaccine will likely need to elicit broadly neutralizing antibodies (bNAbs). Broad and potent VRC01-class bNAbs have been isolated from multiple infected individuals, suggesting that they could be reproducibly elicited by ...
Emilie Seydoux +13 more
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OncoImmunology, 2021 Human microbiota influence the response of malignancies to treatment with immune checkpoint blockade; however, their impact on other forms of immunotherapy is poorly understood.
Duo Yang +12 more
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Advances in the development of personalized neoantigen-based therapeutic cancer vaccines
Nature Reviews Clinical Oncology, 2021 Within the past decade, the field of immunotherapy has revolutionized the treatment of many cancers with the development and regulatory approval of various immune-checkpoint inhibitors and chimeric antigen receptor T cell therapies in diverse indications.
Eryn Blass, P. Ott
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Viruses, 2022 Human T-cell Leukemia virus type-1 (HTLV-1) causes adult T-cell leukemia/lymphoma (ATLL), HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) and other inflammatory diseases.
Cynthia A. Pise-Masison +1 more
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Personalized RNA neoantigen vaccines stimulate T cells in pancreatic cancer
Nature, 2023 Pancreatic ductal adenocarcinoma (PDAC) is lethal in 88% of patients^ 1 , yet harbours mutation-derived T cell neoantigens that are suitable for vaccines ^ 2 , 3 .
Luis A. Rojas +50 more
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Nature Communications, 2023 HIV vaccine development can be aided by knowledge of correlates of protection. Here the authors identify engagement and reprogramming of tolerogenic CD14+ myeloid cells mediating a spatiotemporal balance of pro- and anti-inflammatory responses, as ...
Massimiliano Bissa +34 more
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