Results 11 to 20 of about 163,730 (308)
Philosophical Transactions of the Royal Society B: Biological Sciences, 2011 Abstract While vaccines are primarily thought of in terms of their use for prevention of infectious diseases, they can potentially be used to prevent or treat cancer. This manuscript explores the rationale for vaccines and immunotherapies for cancer from both the scientific and the global needs perspectives.
Margaret A. Liu
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The Changing Landscape of Therapeutic Cancer Vaccines-Novel Platforms and Neoantigen Identification.
, 2021 Therapeutic cancer vaccines, an exciting development in cancer immunotherapy, share the goal of creating and amplifying tumor-specific T-cell responses, but significant obstacles still remain to their success.
Harrington, KJ +4 more
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Targeting tumor heterogeneity with neoantigen-based cancer vaccines
, 2023 Neoantigen-based cancer vaccines have emerged as a promising immunotherapeutic approach to treat cancer. Nevertheless, the high degree of heterogeneity in tumors poses a significant hurdle for developing a vaccine that targets the therapeutically ...
Chen, Shuxiong +5 more
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Cancer Vaccines and Immunotherapy for Tumor Prevention and Treatment
, 2021 In this editorial, we highlight articles published in this Special Issue of Vaccines on “Cancer Vaccines and Immunotherapy for Tumor Prevention and Treatment”, recent developments in the field of cancer vaccines, and the potential for immunotherapeutic ...
Jagmohan Singh +5 more
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EBioMedicine, 2021 Background: Recent studies have provided evidence of T cell reactivity to Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) in significant numbers of non-infected individuals, which has been attributed to cross-reactive CD4 memory T cells from
Isaac Quiros-Fernandez +3 more
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Trends in Pharmacological Sciences, 1993 1993 represents the 100th anniversary of William Coley's first report of tumor regressions induced by immune system activation in response to bacterial toxins. While many subsequent cancer vaccine trials have yielded tantalizing results, active immunotherapy has not yet become an established modality of cancer therapy.
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Aging, cancer, and cancer vaccines [PDF]
Immunity & Ageing, 2012 AbstractWorld population has experienced continuous growth since 1400 A.D. Current projections show a continued increase - but a steady decline in the population growth rate - with the number expected to reach between 8 and 10.5 billion people within 40 years.
MAZZOLA, PAOLO +6 more
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Cancer Vaccines for Genitourinary Tumors: Recent Progresses and Future Possibilities
, 2021 Background: In the last years, many new treatment options have widened the therapeutic scenario of genitourinary malignancies. Immunotherapy has shown efficacy, especially in the urothelial and renal cell carcinomas, with no particular relevance in ...
Evaristo Maiello +6 more
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npj Vaccines, 2023 Development of SARS-CoV-2 vaccines that protect vulnerable populations is a public health priority. Here, we took a systematic and iterative approach by testing several adjuvants and SARS-CoV-2 antigens to identify a combination that elicits antibodies ...
Etsuro Nanishi +30 more
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Cancer Microenvironment and Cancer Vaccine [PDF]
Cancer Microenvironment, 2012 The cancer microenvironment is constituted of non-transformed host stromal cells such as endothelial cells, fibroblasts, various immune cells, and a complex extra-cellular matrix secreted by both the normal and neoplastic cells embedded in it. The importance of the microenvironment and its potential in cancer therapy is just being established.
Zhen-Yu, Ding +2 more
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