Results 11 to 20 of about 5,770,101 (353)
Therapeutic cancer vaccines: advancements, challenges and prospects
Signal Transduction and Targeted Therapy, 2023 With the development and regulatory approval of immune checkpoint inhibitors and adoptive cell therapies, cancer immunotherapy has undergone a profound transformation over the past decades.
Ting Fan +5 more
semanticscholar +1 more source
Cancer vaccines as promising immuno-therapeutics: platforms and current progress
Journal of Hematology & Oncology, 2022 Research on tumor immunotherapy has made tremendous progress in the past decades, with numerous studies entering the clinical evaluation. The cancer vaccine is considered a promising therapeutic strategy in the immunotherapy of solid tumors.
Jian Liu +5 more
semanticscholar +1 more source
Structural basis for potent neutralization of SARS-CoV-2 and role of antibody affinity maturation
Nature Communications, 2020 Currently there is neither a vaccine nor an effective treatment strategy available for COVID19. Here, Hurlburt et al. provide the crystal structure of a patient-derived monoclonal antibody neutralizing SARS-CoV-2 via shedding of the S1 subunit and ...
Nicholas K. Hurlburt +9 more
doaj +1 more source
Transcriptomic profiling of tumor-infiltrating CD4 + TIM-3 + T Cells reveals their suppressive, exhausted, and metastatic characteristics in colorectal cancer patients [PDF]
, 2020 T cell immunoglobulin mucin-3 (TIM-3) is an immune checkpoint identified as one of the key players in regulating T-cell responses. Studies have shown that TIM-3 is upregulated in the tumor microenvironment (TME).
Abu Nada, M +10 more
core +2 more sources
A Comprehensive Review on Cancer Vaccines and Vaccine Strategies in Hepatocellular Carcinoma
Vaccines, 2023 HCC, the most prevalent form of primary liver cancer, presents a substantial global health challenge due to its high mortality and limited therapeutic options. This review delves into the potential of cancer vaccines as a novel therapeutic avenue for HCC.
Alireza Tojjari +5 more
semanticscholar +1 more source
Advances in mRNA-Based Cancer Vaccines
Vaccines, 2023 Cancer is a leading cause of death worldwide, accounting for millions of deaths every year. Immunotherapy is a groundbreaking approach for treating cancer through harnessing the power of the immune system to target and eliminate cancer cells.
Ling Ni
semanticscholar +1 more source
Human papillomavirus and HPV vaccines: a review [PDF]
, 2007 Cervical cancer, the most common cancer affecting women in developing countries, is caused by persistent infection with "high-risk" genotypes of human papillomaviruses (HPV). The most common oncogenic HPV genotypes are 16 and 18, causing approximately 70%
Castellsague, X. +10 more
core +3 more sources
Cancer vaccines: Building a bridge over troubled waters.
Cell, 2022 Cancer vaccines aim to direct the immune system to eradicate cancer cells. Here we review the essential immunologic concepts underpinning natural immunity and highlight the multiple unique challenges faced by vaccines targeting cancer.
Maclean C Sellars +2 more
semanticscholar +1 more source
Primary Care: Clinics in Office Practice, 2011 The term cancer vaccines encompasses 2 different types of vaccines. Prophylactic vaccines block infection by viruses that can alter host DNA and result in cancer. The hepatitis B vaccine and the human papillomavirus vaccines are examples of prophylactic vaccines that can prevent cancer from developing.
openaire +4 more sources
Cancer Vaccines in the Immunotherapy Era: Promise and Potential
Vaccines, 2023 Therapeutic vaccines are a promising alternative for active immunotherapy for different types of cancers. Therapeutic cancer vaccines aim to prevent immune system responses that are not targeted at the tumors only, but also boost the anti-tumor immunity ...
Chaitenya Verma +6 more
semanticscholar +1 more source