Results 21 to 30 of about 3,308,693 (307)
The transient depletion of monocytes alone prior to exposure of macaques to HTLV-1 enhances both HTLV-1WT (wild type) and HTLV-1p12KO (Orf-1 knockout) infectivity, but seroconversion to either virus is not sustained over time, suggesting a progressive ...
Anna Gutowska +12 more
doaj +1 more source
Purpose: Although local oncolytic viral therapy (OVT) may enhance tumor lysis, antigen release, and adaptive immune responses, systemic antitumor responses post-therapy are limited. Adoptive immunotherapy with autologous dendritic cells (DC) and cytokine-
Jun Ren +13 more
doaj +1 more source
These are exciting times for the field of cancer immunotherapy. Although the clinical efficacy of monoclonal antibodies has been demonstrated since the early 1990s, the therapeutic profile of other immunotherapeutic approaches-especially vaccines-has not yet been formally clarified.
Yaddanapudi, Kavitha +2 more
openaire +2 more sources
Therapeutic cancer vaccines: Where do we stand?
Vaccines and immunotherapy have transformed the treatment modalities and prevention of several diseases including malignancy. Vaccines for infectious diseases have been in use for many decades, but very few cancer vaccines are approved for human use ...
Rajlaxmi Sarangi +4 more
doaj +1 more source
Epitope-based vaccines for cancer
INTRODUCTION Epitope-based cancer vaccination, comprised of minimal immunogenic portions of a cancer antigen, represents an immunotherapy that combines target specifi city with long-lasting immunity. Advances in epitope identifi cation and immunogenicity
core +1 more source
Human Papillomavirus Vaccines: An Updated Review
Human papillomavirus (HPV) vaccines, which were introduced in many countries in the past decade, have shown promising results in decreasing HPV infection and related diseases, such as warts and precancerous lesions. In this review, we present the updated
Cheng, L, +5 more
core +1 more source
The human T-cell leukemia virus type 1 (HTLV-1) is highly dependent on cell-to-cell interaction for transmission and productive infection. Cell-to-cell interactions through the virological synapse, biofilm-like structures and cellular conduits have been ...
Maria Omsland +8 more
doaj +1 more source
Advances in Neoantigen-Based Cancer Vaccines. [PDF]
Neoantigen-based immunotherapies harness somatic mutations as tumor-specific targets and represent a major advance in personalized cancer treatment.
Wu AC, Nakamura Y, Kiyotani K.
europepmc +2 more sources
Improving cellular cancer vaccines [PDF]
Immunization with cancer cells is of great demand in anti-cancer therapy. However, current cellular vaccines are inefficient and there are questions regarding their overall safety. We report a simple and straightforward approach for improving of cellular
Petr Lokhov
core

