Results 41 to 50 of about 5,770,101 (353)

Polysaccharide-based self-assembling nanohydrogels: An overview on 25-years research on pullulan [PDF]

, 2015
The aim of this overview is to review the evolution of the studies carried out, during more than 25 years, on nanohydrogels obtained by self-assembling of pullulan (PUL) using several hydrophobization strategies.
ALHAIQUE, Franco, COVIELLO, Tommasina, DI MEO, Chiara, MATRICARDI, PIETRO, MONTANARI, ELITA   +4 more
core   +1 more source

Cancer Vaccines: Antigen Selection Strategy

Vaccines, 2021
Unlike traditional cancer therapies, cancer vaccines (CVs) harness a high specificity of the host’s immunity to kill tumor cells. CVs can train and bolster the patient’s immune system to recognize and eliminate malignant cells by enhancing immune cells ...
Yue Zhao, Alexey V Baldin, O. Isayev, J. Werner, A. Zamyatnin, A. Bazhin   +5 more
semanticscholar   +1 more source

Adaptive T cell responses induced by oncolytic Herpes Simplex Virus-granulocyte macrophage-colony-stimulating factor therapy expanded by dendritic cell and cytokine-induced killer cell adoptive therapy

OncoImmunology, 2017
Purpose: Although local oncolytic viral therapy (OVT) may enhance tumor lysis, antigen release, and adaptive immune responses, systemic antitumor responses post-therapy are limited. Adoptive immunotherapy with autologous dendritic cells (DC) and cytokine-
Jun Ren, William R. Gwin, Xinna Zhou, Xiaoli Wang, Hongyan Huang, Ni Jiang, Lei Zhou, Pankaj Agarwal, Amy Hobeika, Erika Crosby, Zachary C. Hartman, Michael A. Morse, Kevin H. Eng, H. Kim Lyerly   +13 more
doaj   +1 more source

Virus-like Particles as Preventive and Therapeutic Cancer Vaccines

Vaccines, 2022
Virus-like particles (VLPs) are self-assembled viral protein complexes that mimic the native virus structure without being infectious. VLPs, similarly to wild type viruses, are able to efficiently target and activate dendritic cells (DCs) triggering the ...
A. Tornesello, M. Tagliamonte, F. Buonaguro, M. Tornesello, L. Buonaguro   +4 more
semanticscholar   +1 more source

Complete Rescue of HTLV-1_p12KO Infectivity by Depletion of Monocytes Together with NK and CD8⁺ T Cells

Pathogens
The transient depletion of monocytes alone prior to exposure of macaques to HTLV-1 enhances both HTLV-1WT (wild type) and HTLV-1p12KO (Orf-1 knockout) infectivity, but seroconversion to either virus is not sustained over time, suggesting a progressive ...
Anna Gutowska, Sarkis Sarkis, Mohammad Arif Rahman, Katherine C. Goldfarbmuren, Ramona Moles, Massimiliano Bissa, Melvin Doster, Robyn Washington-Parks, Katherine McKinnon, Isabela Silva de Castro, Luca Schifanella, Genoveffa Franchini, Cynthia A. Pise-Masison   +12 more
doaj   +1 more source

Early Investigations and Recent Advances in Intraperitoneal Immunotherapy for Peritoneal Metastasis. [PDF]

, 2018
Peritoneal metastasis (PM) is an advanced stage malignancy largely refractory to modern therapy. Intraperitoneal (IP) immunotherapy offers a novel approach for the control of regional disease of the peritoneal cavity by breaking immune tolerance.
Bowne, Wilbur B., Katz, Steven C., Khalili, Marian, Morano, William F., Richard, Scott D., Thadi, Anusha   +5 more
core   +2 more sources

Therapeutic cancer vaccines: Where do we stand?

Journal of Integrative Medicine and Research, 2023
Vaccines and immunotherapy have transformed the treatment modalities and prevention of several diseases including malignancy. Vaccines for infectious diseases have been in use for many decades, but very few cancer vaccines are approved for human use ...
Rajlaxmi Sarangi, Srikrushna Mahapatra, Jyotirmayee Bahinipati, Sumit Jhajharia, Tapaswini Pradhan   +4 more
doaj   +1 more source

Vietnamese American women’s beliefs and perceptions on cervical cancer, cervical cancer screening, and cancer prevention vaccines: A community-based participatory study

, 2017
Cervical cancer remains commonly diagnosed in Vietnamese American women. Despite efforts to increase cervical cancer screening among Vietnamese American women, participation rates are persistently lower than the national goal. The objective of this study
Allan, Rachael, Le, Tuong Vy, Nguyen, Kim Quy Vo, Nguyen, Thai Hien, Nguyen-Truong, Connie Kim Yen, Rodela, Keara, Truong, Anthony My   +6 more
core   +3 more sources

Breast Cancer Vaccines: Disappointing or Promising?

Frontiers in Immunology, 2022
Breast cancer has become the most commonly diagnosed cancer globally. The relapse and metastasis of breast cancer remain a great challenge despite advances in chemotherapy, endocrine therapy, and HER2 targeted therapy in the past decades.
Siquan Zhu, Keda Yu
semanticscholar   +1 more source

Evolution of Cancer Vaccines—Challenges, Achievements, and Future Directions

Vaccines, 2021
The development of cancer vaccines has been intensively pursued over the past 50 years with modest success. However, recent advancements in the fields of genetics, molecular biology, biochemistry, and immunology have renewed interest in these ...
Ban Qi Tay, Q. Wright, R. Ladwa, Christopher Perry, G. Leggatt, Fiona Simpson, J. Wells, B. Panizza, I. Frazer, Jazmina L G Cruz   +9 more
semanticscholar   +1 more source