Results 31 to 40 of about 187,608 (218)

Influenza Vaccination Responses in Disabled Stroke Patients: A Single‐Center Prospective Observational Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to investigate the immunological response to influenza vaccination, the incidence and severity of influenza infection, and the side effects of the vaccination in patients with ischemic stroke. Methods This prospective observational study was conducted between 2023 and 2024 at Ramathibodi Hospital.
Achiraya Pakngao, Sureerat Suwatcharangoon, Pintip Ngamjanyapron, Kobporn Boonnak, Thanitta Suangtamai, Porpon Rotjanapan   +5 more
wiley   +1 more source

DataPackageR: Reproducible data preprocessing, standardization and sharing using R/Bioconductor for collaborative data analysis [version 2; referees: 2 approved, 1 approved with reservations]

Gates Open Research, 2018
A central tenet of reproducible research is that scientific results are published along with the underlying data and software code necessary to reproduce and verify the findings.
Greg Finak, Bryan Mayer, William Fulp, Paul Obrecht, Alicia Sato, Eva Chung, Drienna Holman, Raphael Gottardo   +7 more
doaj   +1 more source

The Development of Rheumatoid Arthritis–Specific Ambulatory Care–Sensitive Conditions: Results of a Consensus Process

Arthritis Care &Research, EarlyView.
Objective Ambulatory care–sensitive conditions (ACSCs) serve as indicators of access, quality, and performance of the health system. This study aimed to determine rheumatoid arthritis (RA)‐specific ACSCs for use in the evaluation of care system access and quality.
Kara Irwin, Candace H. Feldman, Claire E. H. Barber, Gabriel Fabreau, Jake Jennings, Scott Patten, Cheryl Barnabe, Inflammatory Arthritis‐Specific ACSC Consensus Process Working Group   +7 more
wiley   +1 more source

Identification of novel interferon responsive protein partners of human leukocyte antigen A (HLA-A) using cross-linking mass spectrometry (CLMS) approach

Scientific Reports, 2022
The interferon signalling system elicits a robust cytokine response against a wide range of environmental pathogenic and internal pathological signals, leading to induction of a subset of interferon-induced proteins.
Ashita Singh, Monikaben Padariya, Jakub Faktor, Sachin Kote, Sara Mikac, Alicja Dziadosz, Tak W. Lam, Jack Brydon, Martin A. Wear, Kathryn L. Ball, Ted Hupp, Alicja Sznarkowska, Borek Vojtesek, Umesh Kalathiya   +13 more
doaj   +1 more source

A Holistic Platform Approach for Developing Robust Pulmonary mRNA Delivery: Integrating Novel Phenolic Acid‐Derived Ionizable Lipids and Device Engineering

Advanced Functional Materials, EarlyView.
An integrated pulmonary mRNA delivery platform combining novel biodegradable syringic acid‐derived ionizable lipids, design‐of‐experiments formulation optimization, and vibrating‐mesh nebulizer engineering enabled stable aerosolization and efficient lung delivery.
Neha Kaushal, Younan Ma, Asad Khanmohammed, Dipen Parande, Hanming Zhang, Saket Dolare, Juliet Chen, Apiwat Wangweerawong, Saswata Karmakar, Hongfeng Deng, Frank Koppenhagen, Shraddha Sharma, Eric Reyes, Sherry He, Lianne Boeglin, Caroline Woo, Azadeh Paksa, Ayed Allawzi, Anusha Dias, Gregory Troiano, Shrirang Karve, Frank DeRosa   +21 more
wiley   +1 more source

Assessing VirScan serosurvey epitope profiling variability between in-clinic venous blood draw and capillary blood self-sampling device

Microbiology Spectrum
Timely and ongoing in-clinic sample collections are a common logistical barrier to volunteer participation and retention in longitudinal clinical studies.
Linda M. Sircy, Terry L. Stevens-Ayers, Elizabeth M. Krantz, Laurel Joncas-Schronce, Nina S. O. Ozbek, Rachel L. Blazevic, Larry Mose, Louise E. Kimball, Ryan Basom, Sayan Dasgupta, Antje Heit, Frank Schmitz, David Heckerman, Rachel A. Bender Ignacio, Joshua A. Hill, Jim Boonyaratanakornkit, Michael Boeckh, Alpana Waghmare   +17 more
doaj   +1 more source

Engineering Antigen Density on M13 Bacteriophage for Personalized Nanovaccine

Advanced Healthcare Materials, EarlyView.
Increasing antigen density on the phage capsid impacts phage uptake and antigen cross‐presentation by antigen‐presenting cells, leading to enhanced activation of antitumor CD8+ T cells in the draining lymph nodes. These activated CD8+ T cells subsequently recognize the antigen‐expressing tumors and mediate their specific cytotoxic killing, thereby ...
Shengnan Huang, Allison Madow, Jack Rudrum, Huaiyao Peng, Hao Nghi Luu, Peiyan Dong, Jifa Qi, Angela M. Belcher   +7 more
wiley   +1 more source

Anti-proliferative therapy for HIV cure: a compound interest approach

Scientific Reports, 2017
In the era of antiretroviral therapy (ART), HIV-1 infection is no longer tantamount to early death. Yet the benefits of treatment are available only to those who can access, afford, and tolerate taking daily pills. True cure is challenged by HIV latency,
Daniel B. Reeves, Elizabeth R. Duke, Sean M. Hughes, Martin Prlic, Florian Hladik, Joshua T. Schiffer   +5 more
doaj   +1 more source

Programmable Carrier‐Free All‐Enzyme Beads for Modular Continuous‐Flow Biocatalysis

Advanced Materials, EarlyView.
Genetically encoded enzyme building blocks self‐assemble into monodisperse, carrier‐free protein beads via a droplet‐based formulation strategy. These programmable catalytic particles enable modular continuous‐flow biocatalysis, from single‐enzyme reactions to multi‐enzyme cascades and bead–bead coupled reactor systems.
Jennifer Kühne, Julian S. Hertel, André Delavault, Judith Felk, Martin Peng, Lara Reuber, Felix Ott, Kim Wanner, Marc F. Münker, Adrian Neukirch, Alexei Kiselev, Kersten S. Rabe, Christof M. Niemeyer   +12 more
wiley   +1 more source

Development of a potent monoclonal antibody for treatment of human metapneumovirus infections

Nature Communications
Human metapneumovirus (HMPV) is a major cause of respiratory infections, particularly among vulnerable populations, yet effective therapeutics remain unavailable. Monoclonal antibodies (mAbs) offer a promising approach for treatment and prevention.
Evelyn D. Harris, Morgan McGovern, Sara Pernikoff, Ren Ikeda, Lea Kipnis, William Hannon, Elizabeth B. Sobolik, Matthew Gray, Alexander L. Greninger, Sijia He, Chen-Ni Chin, Tong-Ming Fu, Marie Pancera, Jim Boonyaratanakornkit   +13 more
doaj   +1 more source