Results 81 to 90 of about 46,556 (258)
Structural dynamics and pH‐regulated membrane binding of the TRAF2‐NC trimer
Abstract Tumor necrosis factor receptor‐associated factor 2 (TRAF2) is a key adaptor in TNF receptor‐signaling that operates as a trimeric assembly. Here we investigate the structural and functional properties of a TRAF2 construct spanning the trimerization and receptor‐binding domains (TRAF2‐NC, residues 266–501).
Federica Cossu +9 more
wiley +1 more source
Targeting tumor-specific metabolic adaptations is a promising anticancer strategy when tumor defense mechanisms are restrained. Here, we show that redox-modulating drugs including the retinoid N-(4-hydroxyphenyl)retinamide (4HPR), the synthetic ...
Roberta Venè +9 more
doaj +1 more source
INTRODUÇÃO: O rastreio do cancro da mama é realizado através da mamografia nas mulheres. O objetivo desta revisão foi avaliar se a mamografia de rastreio diminui a mortalidade por cancro da mama.
S. Alves, Bernardo Pereira, I. Peixoto
semanticscholar +1 more source
Although human papillomavirus (HPV) testing is recommended for cervical cancer screening in low‐ and middle‐income countries, optimal management of HPV‐positive women remains undetermined, particularly in resource‐limited settings. Here, using data from the 3T study involving women in Cameroon, the authors evaluated the ability of extended HPV ...
Micol Murtas +11 more
wiley +1 more source
Background: Colorectal cancer survival is better in hereditary nonpolyposis colorectal cancer patients than in sporadic colorectal cancer patients and even for hereditary nonpolyposis colorectal cancer with colorectal cancer is not consensual that ...
Marisa D. Santos +8 more
doaj +1 more source
Characterization of the Interaction of Known G‐quadruplex Ligands With a Minimal i‐Motif Structure
The destabilization of a minimal i‐Motif (iM) structure by TMPyP4 is driven by ligand recognition of one terminal iM structural domain. ABSTRACT Peculiar genomic regions are prone to evolve transiently from double‐helix DNA to noncanonical secondary structures in response to physiological stress.
Davide Auricchio +3 more
wiley +1 more source
Inibidores de immune checkpoint são uma promessa na luta contra o cancro do pulmão e outros tumores malignos, alterando o microambiente do tumor e bloqueando a evasão ao sistema imunitário.
Maria Bárbara Parente
doaj +1 more source
Turnaround Time Trends in Cervical Cytology Screening in South Africa, 2005–2023
ABSTRACT Background Timely cervical cytology results are crucial for effective screening and early management of precancerous lesions. However, many low‐ and middle‐income countries face delays in turnaround time (TAT). This study assessed TAT for cytology screening results in South Africa from 2005 to 2023 and identified factors associated with TAT ...
Sizeka Mashele +8 more
wiley +1 more source
Ameixeira (Prunus domestica L.): cancro bacteriano [Fruto]
Apresenta o cancro bacteriano em frutos da ameixeiraComponente Curricular::Educação Superior::Ciências Agrárias ...
Del Ponte, Emerson Medeiros
core
Determinação da atividade anti tumoral de derivados quirais de xantonas
João Sousa +4 more
doaj +1 more source

