A single‐cell atlas of cerebrospinal fluid in Alzheimer's disease [PDF]
Alzheimer's &Dementia, Volume 21, Issue S1, December 2025.Abstract Background Potential differences in immune characteristics between sporadic late‐onset Alzheimer's disease (sLOAD) and sporadic late‐onset AD (sEOAD) have not been well elucidate. Immune cells in the cerebrospinal fluid (CSF) can reflect the brain immune system dysregulation of patients.
Jun Lin, Jiong Shi
wiley +2 more sources
Different Role of CSF MMPs in Amyloid Pathology and Cerebrovascular Pathology [PDF]
Alzheimer's &Dementia, Volume 21, Issue S2, December 2025.Abstract Background Amyloid and cerebrovascular pathologies play critical role in the pathogenesis of Alzheimer's disease (AD). Matrix metalloproteinases (MMPs) is known to degrade Aβ peptides, while they also contribute to cerebrovascular pathology. Presently, the precise roles of MMPs in AD remain unclear.
Feng Gao, Yaxi Zhan, Yong Shen
wiley +2 more sources
CSF NPTXs sensitively monitor neurodegeneration and cognitive decline in the Alzheimer's disease continuum [PDF]
Alzheimer's &Dementia, Volume 21, Issue S2, December 2025.Abstract Background Identifying reliable and sensitive biomarkers to track neurodegeneration and cognitive impairment in Alzheimer's Disease (AD) is crucial for staging the severity of the disease. Method This study enrolled 435 participants from the China Aging and Neurodegenerative Disorder Initiative (CANDI) cohort from 2018 through 2023.
Linbin Dai, Feng Gao, Yong Shen
wiley +2 more sources
Treatment outcomes in pediatric intestinal failure patients with ambulatory Candida central line‐associated bloodstream infections with and without central venous line removal: A retrospective case series [PDF]
Nutrition in Clinical Practice, Volume 40, Issue 5, Page 1139-1145, October 2025.Abstract Background Lack of central venous line (CVL) sites is a common indication for intestinal transplantation in intestinal failure (IF) patients. For treatment of central line‐associated bloodstream infections (CLABSIs), many pediatric gastroenterologists preserve CVL access, but line removal is typically recommended for Candida sp CLABSI due to ...
Hamza Hassan Khan +5 more
wiley +2 more sources
Cerebrospinal fluid NPTXR changes and relationships with β‐amyloid load and metabolism by PET in Alzheimer’s disease [PDF]
Alzheimer's &Dementia, Volume 21, Issue S7, December 2025.Abstract Background Neuronal pentraxin receptor (NPTXR) has been identified as a cerebrospinal fluid (CSF) biomarker associated with synaptic pathology, demonstrating its significant correlation with progressive cognitive impairment in Alzheimer’s disease (AD).
Ming Ni +5 more
wiley +2 more sources
Multi‐omic characterization of consensus molecular subtype 1 (CMS1) colorectal cancer with dampened immune response improves precision medicine [PDF]
Molecular Oncology, Volume 19, Issue 12, Page 3486-3498, December 2025.This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti +10 more
wiley +2 more sources
KAJIAN PENGENDALIAN KETERANCAMAN CANDI TEBING KELEBUTAN AKIBAT ALIRAN AIR DAN TANAMAN
Jurnal Ilmiah Teknik Sipil, 2023 Abstrak: Keterancaman candi tebing kelebutan oleh aliran air dan tumbuhan pohon-pohon besar seperti pohon kelapa, pohon pisang sangat nyata terjadi. Sawah yang ada di belakang atau di sebelah timur candi tebing ini menahan air dan tentu saja air sawah ...
I Wayan Redana
doaj +1 more source
Jurnal Ilmiah Manajemen dan Bisnis, 2020 The purpose of this study is to analyze the influence spiritual leadership and reward toward employee performance with quality of work life and job satisfaction as mediating variable.
Padmayuda Tri Rachmawan, Dwi Nita Aryani
doaj +1 more source
Pemodelan Representasi Pengetahuan Berbasis OWL untuk Objek Arsitektur Candi di Indonesia
JUTEI (Jurnal Terapan Teknologi Informasi), 2021 Candi merupakan salah satu contoh warisan budaya. Jumlah candi Indonesia yang banyak membuat informasi yang tersebar di internet juga sangatlah banyak. Namun informasi tersebut bukanlah suatu kesatuan informasi.
Thalia Maria Camilo +3 more
doaj +1 more source
Busana Bangsawan Dan Pendeta Wanita Pada Masa Majapahit: Kajian Berdasarkan Relief-Relief Candi
Berkala Arkeologi, 1999 Dalam tulisan ini akan dilakukan terhadap kajian pada relief candi di Jawa Timur, dimana candi-candi tersebut dibangun pada masa kerajaan Majapahit berkuasa.
Hari Lelono
doaj +3 more sources