MRD-negative conversion with daratumumab monotherapy in newly diagnosed multiple myeloma patients in ≥VGPR/MRD-positive after first-line therapy: Final analysis of the open-label, single-arm multicentric phase 2 trial DART4MM. [PDF]
Br J HaematolIn newly diagnosed multiple myeloma patients in ≥Very Good Partial Remission (VGPR) after a first‐line therapy daratumumab as consolidation/maintenance improved long‐term minimal residual disease negativity. Summary Daratumumab is approved for front‐line and relapsed myeloma therapy.
Gozzetti A +24 more
europepmc +2 more sources
Multimodal Integration of Gait Dysfunction, Amyloid PET, and Plasma Biomarkers for Differentiating Etiological Subtypes in Mild Cognitive Impairment. [PDF]
CNS Neurosci TherThis study demonstrates that dual‐task gait assessments combined with plasma biomarkers (GFAP and p‐tau217) significantly improve the discrimination of amyloid‐positive mild cognitive impairment (MCI+) from both cognitively normal individuals and amyloid‐negative MCI.
Wu J +7 more
europepmc +2 more sources
A single‐cell atlas of cerebrospinal fluid in Alzheimer's disease [PDF]
Alzheimers DementAbstract Background Potential differences in immune characteristics between sporadic late‐onset Alzheimer's disease (sLOAD) and sporadic late‐onset AD (sEOAD) have not been well elucidate. Immune cells in the cerebrospinal fluid (CSF) can reflect the brain immune system dysregulation of patients.
Lin J, Shi J.
europepmc +2 more sources
Different Role of CSF MMPs in Amyloid Pathology and Cerebrovascular Pathology [PDF]
Alzheimers DementAbstract Background Amyloid and cerebrovascular pathologies play critical role in the pathogenesis of Alzheimer's disease (AD). Matrix metalloproteinases (MMPs) is known to degrade Aβ peptides, while they also contribute to cerebrovascular pathology. Presently, the precise roles of MMPs in AD remain unclear.
Gao F, Zhan Y, Shen Y.
europepmc +2 more sources
KAJIAN PENGENDALIAN KETERANCAMAN CANDI TEBING KELEBUTAN AKIBAT ALIRAN AIR DAN TANAMAN
Jurnal Ilmiah Teknik Sipil, 2023 Abstrak: Keterancaman candi tebing kelebutan oleh aliran air dan tumbuhan pohon-pohon besar seperti pohon kelapa, pohon pisang sangat nyata terjadi. Sawah yang ada di belakang atau di sebelah timur candi tebing ini menahan air dan tentu saja air sawah ...
I Wayan Redana
doaj +1 more source
Pemodelan Representasi Pengetahuan Berbasis OWL untuk Objek Arsitektur Candi di Indonesia
JUTEI (Jurnal Terapan Teknologi Informasi), 2021 Candi merupakan salah satu contoh warisan budaya. Jumlah candi Indonesia yang banyak membuat informasi yang tersebar di internet juga sangatlah banyak. Namun informasi tersebut bukanlah suatu kesatuan informasi.
Thalia Maria Camilo +3 more
doaj +1 more source
Jurnal Ilmiah Manajemen dan Bisnis, 2020 The purpose of this study is to analyze the influence spiritual leadership and reward toward employee performance with quality of work life and job satisfaction as mediating variable.
Padmayuda Tri Rachmawan, Dwi Nita Aryani
doaj +1 more source
Kualitas Pentatahan Relief Di Kompleks Candi Prambanan
Berkala Arkeologi, 1996 Apakah ada hubungan antara teknik pentatahan dengan tema cerita? Seperti diketahui pada Candi Ciwa dan Brahma (cerita Ramayana) mengisahkan perjalanan seorang bangsawan atau raja, sehingga memerlukan asesoris yang lengkap.
Hari Lelono
doaj +3 more sources
Busana Bangsawan Dan Pendeta Wanita Pada Masa Majapahit: Kajian Berdasarkan Relief-Relief Candi
Berkala Arkeologi, 1999 Dalam tulisan ini akan dilakukan terhadap kajian pada relief candi di Jawa Timur, dimana candi-candi tersebut dibangun pada masa kerajaan Majapahit berkuasa.
Hari Lelono
doaj +3 more sources