Results 91 to 100 of about 688,240 (400)

Epidemiology, clinical characteristics, resistance, and treatment of infections by Candida auris

Journal of Intensive Care, 2018
Candida spp. infections are a major cause of morbidity and mortality in critically ill patients. Candida auris is an emerging multi-drug-resistant fungus that is rapidly spreading worldwide.
A. Cortegiani, G. Misseri, T. Fasciana, A. Giammanco, A. Giarratano, A. Chowdhary   +5 more
semanticscholar   +1 more source

Advancing Clinical Medicine with Raman Spectroscopy: Current Trends and Future Perspectives

Advanced Photonics Research, EarlyView.
Raman spectroscopy and microscopy may become excellent tools in clinical medicine, including hematology, oncology, infectious diseases, neurology, gastroenterology, reproductive medicine, rheumatology, and cardiovascular research. However, many challenges such as signal interference, standardization issues, and limited clinical application need to be ...
Jiří Bufka, Lenka Vaňková, Josef Sýkora, Věra Křížková, Jan Schwarz, Petr Bouř   +5 more
wiley   +1 more source

Amide and Thioester Synthesis Via Oxidative Coupling of Alcohols with Amines or Thiols Using Alcohol Dehydrogenases

Angewandte Chemie, EarlyView.
Alcohol dehydrogenases (ADHs) are best known for reducing ketones to chiral alcohols, but their oxidative potential is rarely exploited. Here, we show that selected ADHs catalyze newly discovered promiscuous transformations: the oxidative coupling of primary alcohols with amines or thiols, enabling the direct and efficient synthesis of a broad range of
Matteo Damian, Vasilis Tseliou, Patrick Peters, Tanja Knaus, Francesco G. Mutti   +4 more
wiley   +2 more sources

Lifting Activities Assessment Using Lumbosacral Compression and Shear Forces

Applied Sciences
In this study, we have analyzed the behavior of shear and compression forces at the L5-S1 joint during the execution of controlled lifting tasks designed on the basis of the revised NIOSH (National Institute for Occupational Safety and Health) lifting ...
Tiwana Varrecchia, Giorgia Chini, Mariano Serrao, Alberto Ranavolo   +3 more
doaj   +1 more source

Candida on oral cavity of pediatric individuals with ALL and its susceptibility to nystatin and amphotericin B

RGO: Revista Gaúcha de Odontologia, 2019
Objective: The aim of this study was to evaluate the prevalence of Candida colonizationon oral cavity of pediatric individuals with acute lymphocytic leukemia (ALL) and its susceptibility/resistance to nystatin and amphotericin B.
Larissa Cavalcanti MONTEIRO, Isabella Lima Arrais RIBEIRO, Roberta Ferreti Bonan Dantas BATISTA, Panmella Pereira MACIEL, Ana Maria Gondim VALENÇA, Ana Carolina Bernardes DULGHEROFF4 , Joelma Rodrigues SOUZA, Yuri Wanderley CAVALCANTI1 , Lucio Roberto Cançado CASTELLANO, Paulo Rogério Ferreti BONAN   +9 more
doaj   +1 more source

Structural, Mechanical, and Genetic Insights into Heat‐Pressed Fomes Fomentarius Mycelium from Solid‐State and Liquid Cultivations

Advanced Sustainable Systems, EarlyView.
Fungal mycelium‐based materials are an upcoming class of sustainable materials. Heat ‐pressing is a promising post‐processing technique to produce fungal mycelium‐based particle boards or leather substitutes. However, little is known about the mechanism involved.
Huaiyou Chen, Sophie Klemm, Ernesto Scoppola, Bertram Schmidt, Yunpeng Wu, Claudia Fleck, Aleksander Gurlo, Vera Meyer, Carsten Freidank‐Pohl, Ulla Simon   +9 more
wiley   +1 more source

Lower Limb Muscle Co-Activation Maps in Single and Team Lifting at Different Risk Levels

Applied Sciences
The central nervous system uses muscle co-activation for body coordination, effector movement control, and joint stabilization. However, co-activation increases compression and shear stresses on the joints.
Giorgia Chini, Tiwana Varrecchia, Mariano Serrao, Alberto Ranavolo   +3 more
doaj   +1 more source

Homeostasis of Gut Microbiota Protects against Susceptibility to Fungal Pneumonia

Advanced Science, EarlyView.
Fungal pneumonia induces inflammation, shown by heightened IL‐6, IL‐1β, TNF‐α levels and a growth in Staphylococcus in the alveolar flora. The gut microbiota, acting through the gut‐lung axis via blood, impacts fungal pneumonia susceptibility by altering lung metabolism and inflammatory responses.
Jian Ji, Yongli Ye, Jiadi Sun, Lina Sheng, Jinyou Li, Jin Yang, Bing Wu, Yuting Wang, Xingxing Gao, Liang Luo, Jianfeng Ping, Yinzhi Zhang, Xiulan Sun   +12 more
wiley   +1 more source

Surface disinfection challenges for Candida auris: an in-vitro study [PDF]

, 2018
The emerging pathogenic multidrug-resistant yeast Candida auris is an important source of healthcare-associated infections and of growing global clinical concern.
Akinbobola, A., Jones, B.L., Kean, R., MacKay, W.G., McKloud, E., Ramage, G., Sherry, L., Short, B., Townsend, E., Williams, C.   +9 more
core   +4 more sources

Calhm6 Governs Macrophage Polarization Through Chp1‐Camk4‐Creb1 Axis and Ectosomal Delivery in Inflammatory Responses

Advanced Science, EarlyView.
Calhm6 drives M2 macrophage polarization via the Chp1‐Camk4‐Creb1 axis, suppressing inflammation through calcium‐dependent ectosomal delivery. Calhm6 deficiency enhances M1 responses, boosting bactericidal activity but exacerbating tissue damage. LPS/IFNγ upregulate Calhm6 via Irf1, while IL‐4/Stat6 inhibits it, balancing immune outcomes.
Yanlong Xin, Xiaofan Xiong, Yan Zhang, Siyu Zhang, Shuting Zhang, Yu Yang, Yingxue Liang, Lulu Zang, Xi Chen, Wenjuan Li, Issam Halalmeh, Rui Zhou, Zongfang Li, Haowen Liu, Jing Geng   +14 more
wiley   +1 more source