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Candida albicans—The Virulence Factors and Clinical Manifestations of Infection
Candida albicans is a common commensal fungus that colonizes the oropharyngeal cavity, gastrointestinal and vaginal tract, and healthy individuals’ skin. In 50% of the population, C. albicans is part of the normal flora of the microbiota.
J. Talapko +6 more
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Pathogenesis and virulence of Candida albicans
Candida albicans is a commensal yeast fungus of the human oral, gastrointestinal, and genital mucosal surfaces, and skin. Antibiotic-induced dysbiosis, iatrogenic immunosuppression, and/or medical interventions that impair the integrity of the ...
J. P. Lopes, M. Lionakis
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Biofilm Formation in Medically Important Candida Species
Worldwide, the number of infections caused by biofilm-forming fungal pathogens is very high. In human medicine, there is an increasing proportion of immunocompromised patients with prolonged hospitalization, and patients with long-term inserted drains ...
Z. Malinovská, E. Čonková, P. Váczi
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Candida parapsilosis is the second most common Candida species isolated in Asia, Southern Europe, and Latin America and is often involved in invasive infections that seriously impact human health. This pathogen is part of the psilosis complex, which also
Joana Branco, I. Miranda, A. Rodrigues
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Antifungal drug-resistance mechanisms in Candida biofilms
Infections caused by the Candida species of human fungal pathogens are a significant medical problem because they can disseminate to nearly every organ of the body. In addition, there are only a few classes of antifungal drugs available to treat patients
Jaspreet Kaur, C. Nobile
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Oral Cavity and Candida albicans: Colonisation to the Development of Infection
Candida colonisation of the oral cavity increases in immunocompromised individuals which leads to the development of oral candidiasis. In addition, host factors such as xerostomia, smoking, oral prostheses, dental caries, diabetes and cancer treatment ...
Mrudula Patel
semanticscholar +1 more source
Antifungal Drug Resistance: Molecular Mechanisms in Candida albicans and Beyond.
Fungal infections are a major contributor to infectious disease-related deaths across the globe. Candida species are among the most common causes of invasive mycotic disease, with Candida albicans reigning as the leading cause of invasive candidiasis ...
Yunjin Lee +3 more
semanticscholar +1 more source
Candida auris: Epidemiology, biology, antifungal resistance, and virulence
First described in 2009 in Japan, the emerging multidrug-resistant fungal pathogen Candida auris is becoming a worldwide public health threat that has been attracting considerable attention due to its rapid and widespread emergence over the past decade ...
Han Du +5 more
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The Fungal Cell Wall: Candida, Cryptococcus, and Aspergillus Species
The fungal cell wall is located outside the plasma membrane and is the cell compartment that mediates all the relationships of the cell with the environment. It protects the contents of the cell, gives rigidity and defines the cellular structure.
R. Garcia-Rubio +3 more
semanticscholar +1 more source
Overview on the Infections Related to Rare Candida Species
Atypical Candida spp. infections are rising, mostly due to the increasing numbers of immunocompromised patients. The most common Candida spp. is still Candida albicans; however, in the last decades, there has been an increase in non-Candida albicans ...
Sunil Kumar +5 more
semanticscholar +1 more source

