Results 241 to 250 of about 408,199 (364)

Vaginal Microbiota and Ovarian Cancer: A New Frontier in Immunomodulation and Diagnosis

open access: yesImmunology, EarlyView.
Microbial imbalance, dysbiosis, plays a role in ovarian carcinogenesis by interacting with the immune system and altering inflammatory pathways, notably Th17 pathways. In contrast, eubiosis, characterised by Lactobacillus dominance, protects against infections and maintains hormone metabolism.
Wafa Babay   +4 more
wiley   +1 more source

Long‐term safety and efficacy of secukinumab in paediatric severe plaque psoriasis: 236‐week, Phase 3 trial results

open access: yesJournal of the European Academy of Dermatology and Venereology, EarlyView.
In this Phase III study, secukinumab demonstrated sustained efficacy and a favourable safety profile in paediatric patients with chronic severe plaque psoriasis over a treatment period of 236 weeks. Abstract Background Plaque psoriasis, a chronic inflammatory disease, affects up to 2.1% of the global paediatric population.
Andrzej Kaszuba   +11 more
wiley   +1 more source

Self‐Adhesive Flowable Resin Composites—Are We Going Somewhere?

open access: yesJournal of Esthetic and Restorative Dentistry, EarlyView.
ABSTRACT Objective To map laboratory/clinical evidence on self‐adhesive flowable resin composites (SAFRCs), tracing their chemical evolution, performance, and behavior, and to identify gaps that must be addressed to drive their optimization. Overview A comprehensive literature search was performed in PubMed/MEDLINE, Scopus, and LILACS without language ...
António H. S. Delgado   +4 more
wiley   +1 more source

Microfluidic live‐cell imaging of Aspergillus fumigatus and Candida albicans hyphal growth treated with AmBisome and Caspofungin

open access: yesJournal of Microscopy, EarlyView.
Abstract Hyphal forms of human pathogenic fungi cause invasive disease in humans, but the hyphal response to antifungals is understudied. In the major fungal pathogens Aspergillus fumigatus and Candida albicans, we used microfluidic‐coupled, fluorescence‐mediated live‐cell imaging to capture the real‐time responses of fungal hyphae to clinical ...
D. D. Thomson   +3 more
wiley   +1 more source

The dysregulation of innate immunity by Porphyromonas gingivalis in the etiology of Alzheimer's disease

open access: yesJournal of Internal Medicine, EarlyView.
Abstract The etiology of Alzheimer's disease (AD) remains under active debate. In this perspective, we explore the hypothesis that a primarily infection‐caused chronic dysregulation and weakening of human innate immunity via the underexpression, degradation, and inactivation of innate immune proteins necessary for direct antimicrobial effects and ...
Annelise E. Barron   +3 more
wiley   +1 more source

Nine-Year Surveillance of Candida Bloodstream Infections in a Southern Italian Tertiary Hospital: Species Distribution, Antifungal Resistance, and Stewardship Implications. [PDF]

open access: yesJ Pers Med
Spera AM   +9 more
europepmc   +1 more source

Effects of pH and Aeration Conditions on Xylitol Production by Candida and Hansenula Yeasts

open access: diamond, 2015
Zoltán Mareczky   +4 more
openalex   +2 more sources

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