Results 51 to 60 of about 350,160 (313)
Uncontrolled use of antimicrobial drugs leads to the selection and spread of resistant strains of microorganisms. Рhosphonium compounds and their derivatives have been chosen as very perspective during searching of new highly active antimicrobial and ...
A. V. Gumenna +4 more
doaj +1 more source
Candida parapsilosis: from Genes to the Bedside
Patients with suppressed immunity are at the highest risk for hospital-acquired infections. Among these, invasive candidiasis is the most prevalent systemic fungal nosocomial infection.
R. Tóth +9 more
semanticscholar +1 more source
ImmuDef, a novel algorithm to quantitatively evaluate the anti‐infection immune defense function of an individual based on RNA‐seq data via a variational autoencoder (VAE) model. It is validated on 3200+ samples across four immune states with high accuracy. It can serve as a metric for disease severity and prognosis across pathogenic cohorts.
Zhen‐Lin Tan +7 more
wiley +1 more source
Evaluation of effect the cyclic lipopeptides from Bacillus atrophaeus HNSQJYH170 on Candida species
Background and Objectives: In humans, during the recent years, several factors have increased the risk of fungal infections, like broad spectrum antibiotics, immune compromised patients, cytotoxic chemotherapy and transplantations.
Solmaz Moghtadi pisheh, Mahboobeh madani
doaj
Untreated tooth decays affect nearly one third of the world and is the most prevalent disease burden among children. The disease progression of tooth decay is multifactorial and involves a prolonged decrease in pH, resulting in the demineralization of ...
Tong Tong Wu +7 more
doaj +1 more source
This study reveals the molecular mechanism by which the transcription factor FgSge1 regulates mycotoxin biosynthesis and virulence in Fusarium graminearum. FgSge1 binds to the TAARGTTT cis‐element, enabling self‐activation. It recruits the SAGA complex, promotes histone acetylation, and facilitates jet‐like chromatin remodeling, thereby activating ...
Yueqi Zhang +6 more
wiley +1 more source
Global epidemiology of emerging Candida auris.
The discovery in 2009 of a new species of yeast, Candida auris, heralded the arrival of a novel emerging human infectious disease. This review highlights the unique characteristics of C. auris that have lled to it being of public health concern worldwide,
J. Rhodes, M. Fisher
semanticscholar +1 more source
Engineering New‐to‐Nature Biological Pathways for β,γ‐Alkanediol Synthesis
β,γ‐Alkanediols are value‐added chemicals to be used as functional solvents, biofuels, and cosmetic components. This work demonstrates a carboligation‐mediated approach for synthesis of linear chain β,γ‐alkanediols in Escherichia coli, namely, hexane‐2,3‐diol (2,3‐HDO) and pentane‐2,3‐diol (2,3‐PDO). The engineered E. coli cells produce 152.2 mm (17.98
Haofeng Chen +6 more
wiley +1 more source
Candidemia is an important cause of morbidity and mortality especially in immunocompromised and hospitalized patients. We retrospectively collected data of candidemia cases that occurred in the seven Hematology-Oncology Departments/Units of Greece and ...
Eleni Vasileiou +13 more
doaj +1 more source
Candida albicans remains the most common aetiology of invasive candidiasis, leading to high morbidity and mortality. Nevertheless, the incidence of candidiasis due to non-C. albicans species, such as Candida parapsilosis, is increasing. Postantifungal effect (PAFE) is relevant for establishing dosage schedules in antifungal therapy, as the frequency of
S, Gil-Alonso +3 more
openaire +1 more source

