Results 61 to 70 of about 408,199 (364)

Synthetic Lethal Therapy Based on Dimorphism for Systemic Infection of Drug‐Resistant Candida albicans

Advanced Science, EarlyView.
To tackle the alarming mortality rate linked to Candida albicans infections, a synthetic lethal strategy precisely aimed at the two distinct forms of this fungus: yeast and hyphae is formulated. Ultimately, through the innovative use of macrophage membranes for drug delivery, the effectiveness of this strategy is substantially boosted while ...
Yang Gao, Jiahe Su, Jiawei Yuan, Qinyan Cao, Yue Wu, Yuyang Xiao, Guang Yang, Ruomu Xia, Jingpeng Yang, Yanan Li, Lina Wu, He Huang, Lingtong Meng   +12 more
wiley   +1 more source

Performance of a hybrid solar collector system in days with stable and less stable radiative regime

International Journal of Sustainable Engineering, 2018
The aim of this work is to analyse the performance of a solar energy collector system for water and air heating in real working conditions. Two coupled mathematical models have been developed.
Qahtan Adnan Abed, Viorel Badescu, Iuliana Soriga   +2 more
doaj   +1 more source

In Vitro Comparison of Antifungal Activity between Epigallocatechin Gallate EGCG) and Nystatin on Candida Sp. Stored Isolates in HIV/AIDS Patients with Oral Candidiasis

Berkala Ilmu Kesehatan Kulit dan Kelamin (Periodical of Dermatology and Venerology), 2021
Background: Oral candidiasis is an oral infection caused by Candida albicans. It is one of the most common opportunistic infections found in patients with Human Immunodeficiency Virus (HIV)/Acquired Immune Deficiency Syndrome (AIDS).
Yusuf Wibisono, Afif Nurul Hidayati, Sawitri Sawitri, Iskandar Zulkarnain, Evy Ervianti, Rahmadewi Rahmadewi, Esti Hendradi, Pepy Dwi Endraswari, Dwi Murtiastutik   +8 more
doaj   +1 more source

Fluconazole resistance in Candida species: a current perspective

Infection and Drug Resistance, 2017
Candida albicans and the emerging non-albicans Candida spp. have significant clinical relevance among many patient populations. Current treatment guidelines include fluconazole as a primary therapeutic option for the treatment of these infections, but it
E. Berkow, S. Lockhart
semanticscholar   +1 more source

Contributions of the Biofilm Matrix to Candida Pathogenesis

Journal of Fungi, 2020
In healthcare settings, Candida spp. cause invasive disease with high mortality. The overwhelming majority of cases are associated with the use of critically-needed medical devices, such as vascular catheters. On the surface of these indwelling materials,
J. Nett, D. Andes
semanticscholar   +1 more source

CsdA‐LaeB Regulatory Hub Contributes to Aspergillus fumigatus Virulence via Fumiquinazoline C Biosynthesis

Advanced Science, EarlyView.
This study identifies a conserved CsdA‐LaeB hub in Aspergillus fumigatus that regulates secondary metabolite fumiquinazoline C (FqC). Disrupting this hub enhances FqC production and virulence, shedding new light on the post‐transcriptional regulatory logic linking secondary metabolism to pathogenicity and offering alternative strategies for diagnostic ...
Zili Song, Hongjiao Zhang, Leixin Ye, Yuxin Lei, Linqi Wang, Xiao Liu, Nayanna M. Mercado Soto, Nancy P. Keller, Berl R. Oakley, Can Zhao, Michael Bromley, Hongwei Liu, Lei Cai, Koon Ho Wong, Wen‐Bing Yin   +14 more
wiley   +1 more source

Empirical anidulafungin therapy increases the treatment efficacy in invasive candidiasis: ERA study results (EraxisR in the Russian Federation)

Онкогематология, 2019
The objective of the study was to evaluate the effectiveness of empirical therapy with anidulafungin in patients with invasive candidiasis in real clinical practice in Russian healthcare institutions.Materials and methods. In a prospective multicenter (n
N. N. Klimko
doaj   +1 more source

Candida albicans [PDF]

Trends in Microbiology, 2019
Pathogens often face zinc restriction due to the action of nutritional immunity - host processes which restrict microbial access to key micronutrients such as zinc and iron. Candida albicans scavenges environmental zinc via two pathways. The plasma membrane transporter Zrt2 is essential for zinc uptake and growth in acidic environments.
openaire   +2 more sources

Bridging Green Chemistry and Circular Economy: A Pathway to Sustainable Polyester Plastics Through Feedstock, Synthesis, and Waste Upcycling

Advanced Science, EarlyView.
This review summarizes green and low‐carbon strategies throughout the entire life cycle of polyester plastics, including sustainable monomer synthesis, optimization polymerization, efficient recycling, and advanced upcycling technologies. The synergistic implementation of these strategies is expected to significantly promote the development of a ...
Jinzhou Li, Junliang Chen, Yingbing Zhang, Li Wang, Pin Gao, Jianping Yang   +5 more
wiley   +1 more source

Lifting Activities Assessment Using Lumbosacral Compression and Shear Forces

Applied Sciences
In this study, we have analyzed the behavior of shear and compression forces at the L5-S1 joint during the execution of controlled lifting tasks designed on the basis of the revised NIOSH (National Institute for Occupational Safety and Health) lifting ...
Tiwana Varrecchia, Giorgia Chini, Mariano Serrao, Alberto Ranavolo   +3 more
doaj   +1 more source