Results 51 to 60 of about 299,477 (352)

Structural analyses of Candida albicans sterol 14α-demethylase complexed with azole drugs address the molecular basis of azole-mediated inhibition of fungal sterol biosynthesis

open access: yesJournal of Biological Chemistry, 2017
With some advances in modern medicine (such as cancer chemotherapy, broad exposure to antibiotics, and immunosuppression), the incidence of opportunistic fungal pathogens such as Candida albicans has increased.
Tatiana Y. Hargrove   +8 more
semanticscholar   +1 more source

Beyond Candida albicans: Mechanisms of immunity to non-albicans Candida species [PDF]

open access: yesCytokine, 2015
The fungal genus Candida encompasses numerous species that inhabit a variety of hosts, either as commensal microbes and/or pathogens. Candida species are a major cause of fungal infections, yet to date there are no vaccines against Candida or indeed any other fungal pathogen.
Natasha Whibley, Sarah L. Gaffen
openaire   +3 more sources

Solid‐State NMR Reveals Reorganization of the Aspergillus fumigatus Cell Wall Due to a Host‐Defence Peptide

open access: yesAngewandte Chemie, EarlyView.
Understanding the mode of action is critical to develop new antifungal drugs. Solid‐state NMR was used to study the reorganization of the Aspergillus fumigatus cell wall by a host‐defence peptide. We identified specific polysaccharides and amino acids that are affected by the peptide.
Ajit Kumar Bishoyi   +5 more
wiley   +2 more sources

The Validity of Point-of-Care Test (POCT) Lateral Flow Immunochromatographic Assay (LFIA) Candida albicans for the Diagnosis of Vulvovaginal Candidiasis

open access: yesBerkala Ilmu Kesehatan Kulit dan Kelamin (Periodical of Dermatology and Venerology)
Background: Vulvovaginal candidiasis is one of the most common causes of complaints of vaginal discharge, which is mostly caused by Candida albicans. The common diagnosis of vulvovaginal candidiasis is microscopic and culture examination.
Monika Puspitasari   +2 more
doaj   +1 more source

Oral candidiasis among African human immunodeficiency virus-infected individuals: 10 years of systematic review and meta-analysis from sub-Saharan Africa

open access: yesJournal of Oral Microbiology, 2017
Oral candidiasis (OC) is the most common opportunistic fungal infection among immunocompromised individuals. This systematic review and meta-analysis reports on the contribution of non-albicans Candida species in causing OC among human immunodeficiency ...
Martha F. Mushi   +5 more
doaj   +1 more source

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

open access: yesFEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu   +17 more
wiley   +1 more source

Analysis of the Candida albicans Phosphoproteome [PDF]

open access: yesEukaryotic Cell, 2015
ABSTRACT Candida albicans is an important human fungal pathogen in both immunocompetent and immunocompromised individuals. C. albicans regulation has been studied in many contexts, including morphological transitions, mating competence, biofilm formation, stress resistance, and cell wall ...
S. D. Willger   +7 more
openaire   +5 more sources

Pathogenesis and Virulence of Candida albicans and Candida glabrata [PDF]

open access: yesPathogens, 2020
Fungal infections in humans have historically received comparatively less attention than those caused by bacteria and viruses. This may, in part, stem from the relative differences in infection prevalence. However, the more widespread use of immunosuppressive therapy, invasive surgery and medical devices in modern medicine has resulted in a more ...
Mariana Henriques, David Williams
openaire   +6 more sources

Cis‐unsaturated sphingolipids support growth of sphingoid base‐deficient yeast but impair plasma membrane integrity

open access: yesFEBS Open Bio, EarlyView.
Sphingoid base structures, the sphingolipid backbones, vary among species. We established yeast cells in which the native sphingoid base was replaced with plant‐type bases containing cis or trans double bonds. This is, to our knowledge, the first eukaryotic model mostly composed of sphingolipids containing cis‐unsaturated sphingoid base, providing a ...
Takashi Higuchi   +5 more
wiley   +1 more source

DAYA HAMBAT EKTRAK DAUN JARAK PAGAR (Jatropha curcas L) TERHADAP PERTUMBUHAN Candida albicans

open access: yesCakradonya Dental Journal, 2019
Candida albicans merupakan jamur flora normal bersifat opportunistik didalam rongga mulut yang dapat menyebabkan terjadinya denture stomatitispada daerah rongga mulut.
Susi susi   +3 more
doaj   +1 more source

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