Results 61 to 70 of about 4,316,987 (297)

Extracellular aspartic protease SAP2 of Candida albicans yeast cleaves human kininogens and releases proinflammatory peptides, Met-Lys-bradykinin and des-Arg(9)-Met-Lys-bradykinin [PDF]

, 2012
Bradykinin-related peptides, universal mediators of inflammation collectively referred to as the kinins, are often produced in excessive amounts during microbial infections.
Guevara-Lora, Ibeth, Faussner, Alexander, Kozik, Andrzej, Guevara Lora, Ibeth, Bras, Grazyna, Bochenska, Oliwia, Rąpała-Kozik, Maria, Rapala-Kozik, Maria   +7 more
core   +1 more source

Chromogenic medium versus PCR–RFLP in the speciation of Candida: a comparative study

BMC Research Notes, 2019
Objective Candida species is implicated in a wide array of clinical infections. Speciation of Candida strains is of prime importance in the epidemiological survey and laboratory diagnosis as there is an upswing of antifungal resistance and changing ...
Sankar Leena Sankari, Krishnan Mahalakshmi, Venkatesan Naveen Kumar   +2 more
doaj   +1 more source

“Rhetoric to Reality”- Efficacy of Punica Granatum Peel Extract on Oral Candidiasis: An In vitro Study [PDF]

Journal of Clinical and Diagnostic Research, 2017
Introduction: Global usage of synthetic drugs inadvertently has resulted in deleterious effects and antimicrobial resistance. Phytoextarcts with therapeutic properties appear to be appropriate substitutes for synthetic drugs.
Preethi Madugula, Sudhakara Reddy, Jyothirmai Koneru, Atla Srinivasa Rao, Rayapureddi Sruthi, Divya Teja Dalli   +5 more
doaj   +1 more source

Epidemiology and Antifungal Susceptibility of Candida Species Isolated from 10 Tertiary Care Hospitals in Iran

Microbiology Spectrum, 2022
In recent decades, the incidence of Candida infections has increased in immunocompromised patients. This multicenter study aimed to evaluate in vitro antifungal activities of 8 antifungal agents against the Candida species isolated from 10 university ...
Parisa Badiee, Teun Boekhout, Pardis Haddadi, Rasoul Mohammadi, Abdolkarim Ghadimi-Moghadam, Jafar Soltani, Ali Zarei Mahmoudabadi, Seyyed Amin Ayatollahi Mousavi, Mohammad Javad Najafzadeh, Kambiz Diba, Ali Reza Salimi-Khorashad, Maneli Amin Shahidi, Fatemeh Ghasemi, Hadis Jafarian   +13 more
doaj   +1 more source

Pathological Signal‐Responsive Nanoplatforms for Sepsis: Integrating Biomarker Sensing With Spatiotemporal Drug Delivery and Immunomodulation

Advanced Science, EarlyView.
Biomarker‐triggered nanoplatforms transform sepsis therapy by coupling pathological sensing with precision drug release. This review reveals how microenvironment‐responsive nanomedicines enable stage‐specific intervention, improve therapeutic efficacy, and minimize systemic toxicity, while highlighting emerging opportunities for AI‐assisted and ...
Yukun Liu, Kang Wang, Kwet Kyawl Yan, Zhikai Xu, Xuan Zhao, Xiangjun Bai, Zhanfei Li, Yuchang Wang   +7 more
wiley   +1 more source

Molecular Identification and Antifungal Susceptibility Profiles of Non-albicans Candida Species Clinical Isolates [PDF]

, 2020
Background: There is an increasing incidence of life-threatening systemic mycoses, specifically fulminant infections by the Candida species in hospitalised patients and in those who are immunocompromised.
Kambiz Diba, Shima Aboutalebian, Khadijeh Makhdoomi   +2 more
core   +1 more source

Evaluation of effect the cyclic lipopeptides from Bacillus atrophaeus HNSQJYH170 on Candida species

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2018
Background and Objectives: In humans, during the recent years, several factors have increased the risk of fungal infections, like broad spectrum antibiotics, immune compromised patients, cytotoxic chemotherapy and transplantations.
Solmaz Moghtadi pisheh, Mahboobeh madani
doaj  

Airway Candida diversity in COPD patients and its differential stimulatory effects on lung inflammation in mice

BMC Pulmonary Medicine
Background The airway microbiome is altered in chronic obstructive pulmonary disease (COPD) individuals with high fungal diversity, which manifests mainly as an increase in the diversity of Candida genera. Acute exacerbation of COPD (AECOPD) is a crucial
Haiyue Liu, Feng Li, Jiaqin Zhang, Meizhen Li, Wenliang Zhu, Yihua Lin, Guolin Hong, Zuheng Liu   +7 more
doaj   +1 more source

Coevolution of Morphology and Virulence in Candida Species [PDF]

Eukaryotic Cell, 2011
ABSTRACTMany of the major human fungal pathogens are known to undergo morphological changes, which in certain cases are associated with virulence. Although there has been an intense research focus on morphology in fungi, very little is known about how morphology evolved in conjunction with a variety of other virulence properties.
Delma S, Thompson, Patricia L, Carlisle, David, Kadosh   +2 more
openaire   +2 more sources

The MoSR‐MoDde1 Regulatory Axis: A Novel Determinant of DMI Sensitivity and a Target for Sustainable Rice Blast Control

Advanced Science, EarlyView.
The transcription factor MoSR governs DMI fungicide sensitivity in Magnaporthe oryzae through dual regulation of ergosterol biosynthesis and the detoxification enzyme MoDde1. Targeting MoDde1 via a small‐molecule inhibitor or host‐induced gene silencing enhances DMI efficacy against rice blast, offering a sustainable disease management strategy ...
Fan‐Zhu Meng, Wen‐Kai Wei, Meng‐Yao Wu, Min‐Zheng Cai, Yu‐Fu Wang, Li Zhao, Shuai Meng, Liang‐Fen Yin, Guido Schnabel, Wei‐Xiao Yin, Chao‐Xi Luo   +10 more
wiley   +1 more source