Non-Candida albicans Candida species: virulence factors and species identification in India [PDF]
Background and Purpose: The predominant cause of candidiasis was Candida albicans which has recently changed to non-Candida albicans Candida (NCAC) (i.e., Candida spp. other than the C. albicans).
Dharmendra Singh +3 more
doaj +1 more source
Azole Resistance in Candida Spp.
The emergence of azole-resistant Candida spp. is a significant problem after long-term treatment of recurrent oropharyngeal candidiasis in HIV-infected patients. Several mechanisms can cause this resistance. An important mechanism of azole resistance is reduced intracellular accumulation of the drug.
Kakeya, Hiroshi +3 more
openaire +3 more sources
Estrogen on Candida spp. of the Vagina: Is there any Effect?
A variety of Candida spp. as the most common fungi in the human body can normally be found in the vagina competing with other microbotes. Their presence is influenced by a variety of conditions in the vaginal environment. The proliferation of Candida spp.
AL-Janabi, Ali +1 more
openaire +2 more sources
Dependence on Dectin-1 Varies With Multiple Candida Species
Four Candida spp. (albicans, glabrata, tropicalis, parapsilosis) cause >95% of invasive Candida infections. C. albicans elicits immune responses via pathogen recognition receptors including C-type lectin-like receptors (CLRs).
Aiysha Thompson +10 more
doaj +1 more source
Intensive care unit-related fluconazole use in Spain and Germany: patient characteristics and outcomes of a prospective multicenter longitudinal observational study [PDF]
Background: Candida spp. are a frequent cause of nosocomial bloodstream infections worldwide. Objective: To evaluate the use patterns and outcomes associated with intravenous (IV) fluconazole therapy in intensive care units in Spain and Germany ...
Wissing, Heimo +7 more
core +1 more source
Simvastatin inhibits planktonic cells and biofilms of Candida and Cryptococcus species
The antifungal activity of some statins against different fungal species has been reported. Thus, at the first moment, the in vitro antifungal activity of simvastatin, atorvastatin and pravastatin was tested against Candida spp.
Raimunda Sâmia Nogueira Brilhante +9 more
doaj +1 more source
Strategic incorporation of unnatural amino acids transforms macrocyclic peptides into drug‐like molecules capable of engaging challenging targets. These building blocks enhance stability, permeability, and bioavailability, accelerating the development of next‐generation peptide therapeutics.
Krishna K. Sharma +5 more
wiley +2 more sources
Extracellular aspartic protease SAP2 of Candida albicans yeast cleaves human kininogens and releases proinflammatory peptides, Met-Lys-bradykinin and des-Arg(9)-Met-Lys-bradykinin [PDF]
Bradykinin-related peptides, universal mediators of inflammation collectively referred to as the kinins, are often produced in excessive amounts during microbial infections.
Guevara-Lora, Ibeth +7 more
core +1 more source
Determination of the activity of fungicides against pathogens of dermatomycoses in domestic animals
The aim of the study was to identify and identify the causative agents of dermatomycosis in dogs and cats and to determine their sensitivity to solutions of ketonazole and chlorhexidine digluconate, which are part of the drug Skinhard.
I. M. Kushnir +6 more
doaj +1 more source
Candida albicans repetitive elements display epigenetic diversity and plasticity [PDF]
Transcriptionally silent heterochromatin is associated with repetitive DNA. It is poorly understood whether and how heterochromatin differs between different organisms and whether its structure can be remodelled in response to environmental signals. Here,
Freire-Benéitez, Veronica +4 more
core +1 more source

