Results 21 to 30 of about 4,107,427 (327)

Identification of Antiviral Drug Candidates against SARS-CoV-2 from FDA-Approved Drugs

Antimicrobial Agents and Chemotherapy, 2020
Drug repositioning is the only feasible option to immediately address the COVID-19 global challenge. We screened a panel of 48 FDA-approved drugs against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) which were preselected by an assay of ...
Sangeun Jeon, Meehyun Ko, Jihye Lee, Inhee Choi, S. Byun, Soonju Park, David Shum, Seungtaek Kim   +7 more
semanticscholar   +1 more source

KDIGO Clinical Practice Guideline on the Evaluation and Management of Candidates for Kidney Transplantation.

Transplantation, 2020
The 2020 Kidney Disease: Improving Global Outcomes (KDIGO) Clinical Practice Guideline on the Evaluation and Management of Candidates for Kidney Transplantation is intended to assist health care professionals worldwide who evaluate and manage potential ...
S. Chadban, C. Ahn, D. Axelrod, B. Foster, B. Kasiske, Vijah Kher, Deepali Kumar, R. Oberbauer, J. Pascual, H. Pilmore, J. Rodrigue, D. Segev, N. Sheerin, K. Tinckam, G. Wong, G. Knoll   +15 more
semanticscholar   +1 more source

Cyclobutanes in Small‐Molecule Drug Candidates

ChemMedChem, 2022
Cyclobutanes are increasingly used in medicinal chemistry in the search for relevant biological properties. Important characteristics of the cyclobutane ring include its unique puckered structure, longer C−C bond lengths, increased C−C π‐character and ...
Marnix R. van der Kolk, Mathilde A. C. H. Janssen, F. Rutjes, D. Blanco‐Ania   +3 more
semanticscholar   +1 more source

राजनीतिक वित्त व्यवस्थापनः निर्वाचन सुधारको अवसर

Nepal Public Policy Review, 2021
यो छोटो लेखमा राजनीतिक वित्तका बारेको सामान्य बुझाई र अर्थ, राजनीतिक वित्त व्यवस्थापनको क्रममा अन्तर्राष्ट्रिय र नेपालको अभ्यास, खास गरी निर्वाचनको क्रममा निर्वाचन गराउने निकाय, सरकार, सुरक्षा निकाय एवं दल वा उम्मेदवारबाट हुने खर्चको प्रवृत्ति; दल र निर ...
Bhoj Raj Pokharel
doaj   +1 more source

A systematic review of SARS-CoV-2 vaccine candidates

Signal Transduction and Targeted Therapy, 2020
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an emerging virus that is highly pathogenic and has caused the recent worldwide pandemic officially named coronavirus disease (COVID-19).
Yetian Dong, Tong Dai, Yujun Wei, Long Zhang, Min Zheng, Fangfang Zhou   +5 more
semanticscholar   +1 more source

WIMP dark matter candidates and searches—current status and future prospects [PDF]

Reports on progress in physics. Physical Society, 2017
We review several current aspects of dark matter theory and experiment. We overview the present experimental status, which includes current bounds and recent claims and hints of a possible signal in a wide range of experiments: direct detection in ...
L. Roszkowski, E. M. Sessolo, S. Trojanowski   +2 more
semanticscholar   +1 more source

Combination of Ruthenium Complex and Doxorubicin Synergistically Inhibits Cancer Cell Growth by Down-Regulating PI3K/AKT Signaling Pathway

Frontiers in Oncology, 2020
Combinational use of drugs has been a common strategy in cancer treatment because of synergistic advantages in reducing dose and toxicity, minimizing or delaying drug resistance.
Ke Lin, Yi Rong, Dan Chen, Zizhuo Zhao, Huaben Bo, Aimin Qiao, Xiaojuan Hao, Jinquan Wang   +7 more
doaj   +1 more source

Scalar Dark Matter candidates [PDF]

, 2003
We investigate the possibility that Dark Matter (dm) could be made of scalar candidates and focus, in particular, on the unusual mass range between a few MeV's and a few GeV's.
Boehm, C., Fayet, P.
core   +3 more sources

Inhibited Maternal Bone Resorption Suppress Fetal Rat Bone Development During Pregnancy

Frontiers in Cell and Developmental Biology, 2020
ObjectiveTo determine the relationship between maternal bone resorption and bone development in fetuses.MethodsFemale SD rats were injected with either fluorescent calcium indicator calcein alone or together with tetracycline 1 week before pregnancy ...
Huanhuan Jia, Huanhuan Jia, Li Rao, Kai Kei Miu, Shuangjie Tang, Wei Chen, Guozhu Yang, Yuying Li, Qingnan Li, Qingnan Li, Jun Chen, Li Lu   +11 more
doaj   +1 more source

Municipalities without elected councils. Causes of insufficient fulfilment of candidate lists in some municipalities in local elections in 2018

Politics in Central Europe, 2021
By means of a qualitative analysis of the sixteen municipalities in the Czech Republic in which additional elections were held in 2019, five variables were identified which may explain why additional elections occurred.
Dvořák Petr, Balík Stanislav
doaj   +1 more source