Results 41 to 50 of about 1,234,477 (312)

E-Government Policy to give their Citizens a ‘Citizen Index Score’ based on which Citizens can Take Part as Voters in the Election

open access: yesJurnal Ilmu Pemerintahan
This study aims to determine the framework related to the Government Policy of determining the Average weightage against each citizen of the country, which will decide the value or impact of the Individual Vote given to the Candidate by the Voter in the ...
Muhammad Younus   +5 more
doaj   +1 more source

Theorising Europeanisation in European Literature: Conceptualisation and Operationalisation

open access: yesAustralian and New Zealand Journal of European Studies, 2021
There has been an extensive academic debate on the impact of the European Union on its member states, on the candidate countries for EU membership and the countries in its geographical neighbourhood.
Daviti Mtchedlishvili
doaj   +1 more source

Candidate and non-candidate genes in behavior genetics

open access: yesCurrent Opinion in Neurobiology, 2013
In this review we discuss recent developments in psychiatric genetics: on the one hand, studies using whole genome approaches (genome-wide association studies (GWAS) and exome sequencing) are coming close to finding genes and molecular variants that contribute to disease susceptibility; on the other candidate genes, such as the serotonin transporter ...
Flint, Jonathan, Munafò, Marcus R
openaire   +5 more sources

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

The chancellor-candidates and the campaign

open access: yes, 2004
The 'presidentialisation' of recent federal elections has made the selection and performance of the 'chancellor-candidates' for the SPD and CDU/CSU an increasingly important factor in German electoral politics.
Hogwood, P.
core   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Introduction Candidates between parties and voters-A triadic relationship in the belgian partitocracy

open access: yes, 2018
The introductory chapter emphasises the general relevance of the study of electoral candidates in representative democracies. It presents the book’s theoretical framework: the triadic delegation and accountability relationship between candidates, voters ...
De Winter, Lieven,   +2 more
core   +1 more source

WHAT COMES NEXT? A Candidate Perspective on the EP Policy Priorities until 2019 [PDF]

open access: yesRomanian Journal of European Affairs, 2014
Promises during electoral campaigns have been the focus of an extensive body of literature. So far, the candidates’ perceptions prior to the moment of policy formulation received little attention.
Sergiu Gherghina
doaj  

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

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