Results 121 to 130 of about 104,177 (305)

The Changing Epidemiology of Breakthrough Invasive Fungal Disease in Allogeneic Hematopoietic Stem Cell Transplant Recipients in the Era of Modified‐Release Posaconazole Prophylaxis

open access: yesTransplant Infectious Disease, EarlyView.
This single‐center retrospective cohort study on 300 allogeneic hematopoietic stem cell transplant recipients from January 2017 to May 2020, in which posaconazole modified release was the most common primary antifungal prophylaxis, demonstrated a breakthrough invasive fungal disease (bIFD) rate of 9%, with associated significant all‐cause mortality at ...
Shio Yen Tio   +7 more
wiley   +1 more source

Clinical Practice Guideline for the Management of Candidiasis: 2016 Update by the Infectious Diseases Society of America.

open access: yesClinical Infectious Diseases, 2016
P. Pappas   +11 more
semanticscholar   +1 more source

A multi‐omics investigation of sarcopenia and frailty: Integrating genomic, epigenomic and telomere length data

open access: yesExperimental Physiology, EarlyView.
Abstract Sarcopenia and frailty are complex geriatric syndromes influenced by a combination of genetic and environmental factors. Recent studies suggest that specific genetic variants, DNA methylation patterns and shortened telomeres are associated with age‐related diseases and might contribute to the development of both sarcopenia and frailty. In this
Valentina Ginevičienė   +10 more
wiley   +1 more source

68 Specific Local Antibody Defect in Chronic Mucocutaneous Candidiasis [PDF]

open access: bronze, 1967
Richard A. Chilgren   +2 more
openalex   +1 more source

Genotype–Phenotype Correlations, Mortality, and Clinical Insights in Keratitis–Ichthyosis–Deafness Syndrome: A Comprehensive Review and Case Report

open access: yesAmerican Journal of Medical Genetics Part A, Volume 197, Issue 11, November 2025.
ABSTRACT Keratosis–ichthyosis–deafness (KID) syndrome is a rare autosomal dominant ectodermal disease caused by mutations in the GJB2 gene, which encodes the gap junction protein Connexin 26 (Cx26) located on Chr. 13q12.11. This study presents the first mortality analysis associated with KID syndrome, focusing on a case report of a Latin American ...
Leslie Patrón‐Romero   +17 more
wiley   +1 more source

Suppression of TRPV5 Regulates Microglia‐Mediated Neuroinflammation Following Status Epilepticus

open access: yesGlia, Volume 73, Issue 11, Page 2289-2304, November 2025.
Main Points TRPV5 is involved in microglial activation following epileptic seizures. TRPV5 upregulation in microglia drives neuroinflammation. TRPV5 inhibition by econazole reduces neuroinflammation via suppressing AKT/NF‐κB/NLRP3 signaling cascade. ABSTRACT Neuroinflammation, predominantly associated with glial activation and the release of various ...
Soojin Park   +4 more
wiley   +1 more source

Systemic and gastrointestinal candidiasis of infant mice after intragastric challenge [PDF]

open access: bronze, 1979
L M Pope   +3 more
openalex   +1 more source

A Review on Aspergillosis in Turkey: As a Main Fungal Disease in Poultry

open access: yesVeterinary Medicine and Science, Volume 11, Issue 6, November 2025.
ABSTRACT Background Aspergillosis, a fungal disease caused by various species of the genus Aspergillus, poses a significant threat to the health and productivity of turkeys. Objective The current review aims to synthesize current knowledge regarding the aetiology, pathogenesis, clinical manifestations, diagnostic methods and management strategies ...
Ansam Naji Aboud Alhassani   +9 more
wiley   +1 more source

Clinical practice guidelines for the management of candidiasis: 2009 update by the Infectious Diseases Society of America.

open access: yesClinical Infectious Diseases, 2009
P. Pappas   +13 more
semanticscholar   +1 more source

Metformin Treatment in PCOS Pregnancies Reduces Maternal Infections and Increases the Risk of Allergies and Eczema in the Offspring: Post Hoc Analyses of Two Randomised Controlled Trials and One Follow‐Up Study

open access: yesBJOG: An International Journal of Obstetrics &Gynaecology, Volume 132, Issue 12, Page 1823-1832, November 2025.
ABSTRACT Objective To evaluate the effect of metformin on immunological outcomes in pregnant women with polycystic ovary syndrome (PCOS) and their offspring. Design Post hoc analyses of two randomised controlled trials (PregMet and PregMet2) and one follow‐up study (PedMet).
Mariell Ryssdal   +7 more
wiley   +1 more source

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