Results 161 to 170 of about 115,566 (252)

Adh1‐Programmed SNF1 Phosphogradients Decrypt Morphogenesis in Candida albicans: Chemical Interrogation Unveils Hyphal Transition Thresholds

open access: yesMicrobial Biotechnology, Volume 19, Issue 3, March 2026.
Based on the ADH1 knockout strain, HAQ was identified through forward/reverse genetic screening of 114 natural products and analysis of protein ligand and protein–protein interactions. With the help of HAQ, a new mechanism for regulating the phosphorylation level of Adh1–SNF1 has been revealed, in which HAQ binds to Adh1 to release dephosphorylation ...
Ziqi Wang   +7 more
wiley   +1 more source

Vaginal‐Derived Potential Probiotics and Their Postbiotics Alleviate Aerobic Vaginitis via Suppressing TLR4/MyD88/NF‐κB Signalling Pathway and Potentially Enhancing Vaginal Barrier

open access: yesMicrobial Biotechnology, Volume 19, Issue 3, March 2026.
Consolidated diagram of the mechanism by which L. crispatus YBR‐01, L. plantarum YBR‐01, and their postbiotics improve AV progression. ABSTRACT Antibiotic therapy is currently challenged by drug resistance and high recurrence in aerobic vaginitis (AV), making it urgent to seek novel strategies. In this study, we selected two potential probiotic strains
Meiyun Tian   +7 more
wiley   +1 more source

Rezafungin in fluconazole-resistant and refractory candidiasis: the first Brazilian experience. [PDF]

open access: yesRev Inst Med Trop Sao Paulo
Kruschewsky WLL   +7 more
europepmc   +1 more source

Pseudolaric Acid B Combats Drug‐Resistant Candida albicans Infection via Dual‐Action Mechanisms of Direct Antifungals and Vaginal Microbiota Restoration

open access: yesMicrobial Biotechnology, Volume 19, Issue 3, March 2026.
We propose a novel therapeutic approach against fungal infection: Pseudolaric acid B directly eradicates C. albicans via Erg11 inhibition and uniquely, restores vaginal microecological homeostasis by promoting probiotic lactobacilli, addressing both the pathogen and the dysbiotic environment.
Tianmeng Shao   +3 more
wiley   +1 more source

Review of Herpes Zoster Occurrence in Patients With Atopic Dermatitis Treated With JAK Inhibitors

open access: yesClinical and Translational Science, Volume 19, Issue 3, March 2026.
ABSTRACT Atopic dermatitis (AD) is a chronic inflammatory skin disease that markedly impairs quality of life. Janus kinase inhibitors (upadacitinib, abrocitinib, and baricitinib) are effective therapies for moderate‐to‐severe AD but are associated with viral reactivation, particularly herpes zoster (HZ), due to immunosuppressive effects on interferon ...
Anna Mandecka   +7 more
wiley   +1 more source

Avian Candidiasis: A Comprehensive Review of Pathogenesis, Diagnosis, and Control. [PDF]

open access: yesVet Sci
Haroun M   +11 more
europepmc   +1 more source

Late diagnosis of paediatric HIV infection in high‐income countries: Lessons from the HIV Perinatal Virtual Clinic

open access: yesHIV Medicine, Volume 27, Issue 3, Page 477-484, March 2026.
Abstract Introduction Timely diagnosis of HIV in children remains a challenge in all settings including low‐prevalence, high‐income countries (HIC). We aimed to characterize the prevalence of late diagnosis, and prior missed diagnostic opportunities among new presentations of paediatric HIV in HIC referred to an international Perinatal Virtual Clinic ...
Carolina Curto   +8 more
wiley   +1 more source

Bimekizumab longer-term safety profile in adult patients with axial spondyloarthritis or psoriatic arthritis: an updated analysis of six phase IIb/III clinical studies. [PDF]

open access: yesRMD Open
Mease PJ   +12 more
europepmc   +1 more source

Dental Care Utilization and Expenditures Among Individuals With Asthma

open access: yesJournal of Public Health Dentistry, Volume 86, Issue 1, Page 152-156, Winter 2026.
ABSTRACT Objectives To examine dental care utilization and health and dental care expenditures among individuals with asthma. Methods Data from the 2022 Medical Expenditure Panel Survey (MEPS) (n = 21,405) were used to examine dental care utilization (any dental, preventive dental, and treatment dental visit) among individuals ≥ 1 year with and without
Shillpa Naavaal, Vaibhavi Mone
wiley   +1 more source

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