Results 161 to 170 of about 85,921 (270)

Aire and Fezf2 Shape the Medullary Thymic Epithelial Cell Immunopeptidome for Central Tolerance

open access: yesImmunology, Volume 179, Issue 3, Page 337-349, November 2026.
Central tolerance is shaped not merely by promiscuous gene expression in medullary thymic epithelial cells (mTECs), but by the subset of self‐peptides ultimately presented on MHC class II molecules. We propose a multilayered framework in which AIRE/Aire and FEZF2/Fezf2, together with specialised differentiation programmes—including thymic mimetic‐cell ...
Geraldo Aleixo Passos   +5 more
wiley   +1 more source

Invasive candidiasis in the ICU - Pathogenesis and management strategy

open access: yes, 1994
How should new and old antifungals be used in the management of invasive candidiasis in ICU patients? A pathogenesis-based management strategy for invasive candidiasis is outlined.
Saunders, G. L., Klugman, K., Lipman, J.
core  

Expert consensus on oral management in autoimmune bullous diseases, erythema multiforme and SJS/TEN

open access: yesJournal of the European Academy of Dermatology and Venereology, Volume 40, Issue 11, Page 1756-1764, November 2026.
This international Delphi study achieved expert consensus on 58 statements guiding the management of oral involvement in autoimmune bullous diseases, erythema multiforme and SJS‐TEN. The recommendations emphasize multidisciplinary care, oral hygiene and tailored topical, systemic and inpatient oral management.
Shalini Nayee   +39 more
wiley   +1 more source

Comparative Study of Clinical Characteristics According to Pain Distribution in Lingual Burning Mouth Syndrome

open access: yesJournal of Oral Rehabilitation, Volume 53, Issue 11, Page 2150-2157, November 2026.
Tongue pain mapping in 256 patients with lingual burning mouth syndrome identified distinct clinical phenotypes according to pain distribution. Wider pain areas were associated with higher pain intensity and poorer oral health‐related quality of life, supporting individualised assessment and targeted management.
Yoohyun Sim   +4 more
wiley   +1 more source

A multicenter study on the profile of fungal infections in children infected with HIV in tertiary hospitals in South Western Nigeria. [PDF]

open access: yesFront Pediatr
Oyedeji OA   +11 more
europepmc   +1 more source

Long‐Term Care of OLP Patients: A Retrospective Study From a Single Hospital Outpatient Clinic

open access: yesJournal of Oral Pathology &Medicine, Volume 55, Issue 10, Page 1121-1136, November 2026.
ABSTRACT Background Oral lichen planus (OLP) is a chronic immune‐mediated disorder with malignant potential. However, its real‐world clinical course remains incompletely characterized. This study aimed to describe the natural clinical–histopathological trajectory of OLP in a single tertiary centre and to identify factors associated with dysplasia and ...
F. Scilla   +8 more
wiley   +1 more source

Real‐World Use of Rezafungin for the Treatment of Challenging Aspergillus Infections

open access: yesMycoses, Volume 69, Issue 11, November 2026.
ABSTRACT Background Aspergillus infections can pose significant treatment challenges, due in part to increasing triazole resistance. Clinical insight is needed to understand the potential for rezafungin, a next‐generation echinocandin with once‐weekly dosing, to address some limitations of current treatments for Aspergillus infections.
Neil Stone   +9 more
wiley   +1 more source

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