Results 51 to 60 of about 3,628 (221)
RGS10 shapes the hemostatic response to injury through its differential effects on intracellular signaling by platelet agonists. [PDF]
, 2018 Platelets express ≥2 members of the regulators of G protein signaling (RGS) family. Here, we have focused on the most abundant, RGS10, examining its impact on the hemostatic response in vivo and the mechanisms involved.
Brass, Lawrence F. +7 more
core +1 more source
Morphine Analgesia Pre-PPCI Is Associated with Prothrombotic State, Reduced Spontaneous Reperfusion and Greater Infarct Size [PDF]
, 2017 Schattauer GmbH Stuttgart.The emergency management of ST-elevation myocardial infarction (STEMI) involves treatment with dual-antiplatelet therapy (DAPT) and primary percutaneous coronary intervention (PPCI). Pain is generally treated with opiates, which
Farag, Mohamed +5 more
core +2 more sources
Clinical and Translational Science, Volume 19, Issue 2, February 2026.ABSTRACT Clinical PGx practice guidelines (PGx guidelines) may have limited generalizability for “marginalized” groups. We proposed the five‐step Real‐World Data for Genome‐Guided Prescribing (ReGGRx) framework and, using All of Us research program (AoU) data, examined its ability to estimate disparities in concordance with and benefit from PGx ...
Ilia Rattsev +2 more
wiley +1 more source
Российский кардиологический журнал, 2021 2020 ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment ...
J.-P. Collet +23 more
doaj +1 more source
Acute coronary syndromes [PDF]
, 2016 In the UK, there are over 80,000 admissions annually with acute coronary syndromes (ACS). Management of ST-elevation myocardial infarction (STEMI) involves primary percutaneous coronary intervention (PCI), which is delivered via dedicated heart attack ...
Kotecha, T, Rakhit, RD
core +1 more source
Cangrelor — Expanding therapeutic options in patients with acute coronary syndrome
Cardiology JournalCangrelor is the only intravenous P2Y12 receptor antagonist. It is an adenosine triphosphate analog that selectively, directly, and reversibly binds to the platelet P2Y12 receptors exerting its antiaggregatory effect. Cangrelor is characterized by linear,
Jacek Kubica +16 more
doaj +1 more source
The Use of Cangrelor in the Treatment of a Patient with COVID-19-Associated Acute Coronary Syndrome
Український журнал серцево-судинної хірургії, 2021 In December 2019, an outbreak of pneumonia caused by a novel coronavirus occurred in Wuhan, Hubei province, spreading rapidly first throughout China and subsequently across Europe, the United States (US), and the rest of the world.
S. V. Salo +4 more
doaj +1 more source
Contemporary NSTEMI management: the role of the hospitalist. [PDF]
, 2019 Non-ST-segment elevation myocardial infarction (NSTEMI) is defined as elevated cardiac biomarkers of necrosis in the absence of persistent ST-segment elevation in the setting of anginal symptoms or other acute event.
Amin, Alpesh +9 more
core +1 more source
9-(4'-dimethylaminophenyl)-2,6,7-trihydroxy-xanthene-3-one is a potentially novel antiplatelet drug which antagonizes the effect of thromboxane A2 [PDF]
, 2018 Background: Currently, used oral antiplatelet drugs are both limited and associated with the risk of treatment failure/resistance. Research in this area is hence highly desired.
Applová, Lenka +8 more
core +1 more source
Case Reports in Cardiology, Volume 2026, Issue 1, 2026.Background Profound thrombocytopenia after tirofiban exposure during primary percutaneous coronary intervention (PCI) is rare but clinically important. Causal attribution may be challenging when unfractionated heparin is coadministered, and the relevance of glucose‐6‐phosphate dehydrogenase (G6PD) deficiency remains uncertain.
Chuanwei Zhao +6 more
wiley +1 more source