Results 71 to 80 of about 3,628 (221)

“Tailored” antiplatelet bridging therapy with cangrelor: moving toward personalized medicine

Platelets, 2022
In the setting of patients with indication to receive dual antiplatelet therapy undergoing surgery or invasive procedures, the risk of perioperative cardiac ischemic events, particularly stent thrombosis, is high, because surgery has a prothrombotic ...
Renato Valenti, Iacopo Muraca, Rossella Marcucci, Francesca Ciatti, Martina Berteotti, Anna Maria Gori, Nazario Carrabba, Angela Migliorini, Niccolò Marchionni, Marco Valgimigli   +9 more
doaj   +1 more source

Therapeutic Errors Associated With Antithrombotic Medications Reported to United States Poison Centers

American Journal of Hematology, Volume 100, Issue 4, Page 561-574, April 2025.
ABSTRACT The objective of this study was to investigate the characteristics and trends of therapeutic errors in non‐healthcare facility settings associated with antithrombotic medications reported to United States Poison Centers by analyzing data from the National Poison Data System from 2000 to 2021.
Emma N. Cravo, Hannah L. Hays, Jaahnavi Badeti, Henry A. Spiller, Natalie I. Rine, Motao Zhu, Gary A. Smith   +6 more
wiley   +1 more source

2015 ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation: Task Force for the Management of Acute Coronary Syndromes in Patients Presenting without Persistent ST-Segment Elevation of the European Society of Cardiology (ESC). [PDF]

, 2015
peer ...
Achenbach, S., Agewall, S., Andreotti, Felicita, Badimon, L., Baigent, C., Baumgartner, H., Bax, Jeroen J., Borger, Michael A., Brotons, Carlos, Bueno, H., Bugiardini, R., Carerj, S., Casselman, F., Chew, Derek P., Collet, Jean-Philippe, Cuisset, T., Erol, C., Fitzsimons, D., Gaemperli, O., Gencer, Baris, Halle, M., Hamm, C., Hasenfuss, Gerd, Hildick-Smith, D., Huber, K., Iliodromitis, E., James, S., Kjeldsen, Keld, LANCELLOTTI, Patrizio, Landmesser, Ulf, Lewis, B. S., Lip, G. Y. H., Mehilli, Julinda, Mueller, Christian, Mukherjee, Debabrata, Patrono, Carlo, Piepoli, M. F., Richter, D., Roffi, Marco, Rosemann, T., Sechtem, U., Steg, P. G., Storey, Robert F., Valgimigli, Marco, Vrints, C., Windecker, Stephan, Zamorano, J. L.   +46 more
core   +1 more source

Impact of Mild Hypothermia As Adjunctive Therapy in Patients With ST‐Elevation Myocardial Infarction: A Meta‐Analysis and Trial Sequential Analysis of Randomized Controlled Trials

Catheterization and Cardiovascular Interventions, Volume 105, Issue 3, Page 543-556, February 15, 2025.
ABSTRACT Background The prevention of reperfusion injury remains an unmet need in ST‐elevation myocardial infarction (STEMI) patients. Several randomized controlled trials (RCTs) evaluated mild hypothermia as adjunctive therapy during STEMI, with conflicting results.
Renzo Laborante, Donato Antonio Paglianiti, Mattia Galli, Giuseppe Patti, Domenico D'Amario   +4 more
wiley   +1 more source

Systematic review and meta-analysis of optimal P2Y₁₂ blockade in dual antiplatelet therapy for patients with diabetes with acute coronary syndrome [PDF]

, 2016
Background: Patients with diabetes are at increased risk of acute coronary syndromes (ACS) and their mortality and morbidity outcomes are significantly worse following ACS events, independent of other comorbidities.
Brown, Oliver I, Hoye, Angela, Rossington, Jennifer A   +2 more
core   +2 more sources

Understanding Drug Interactions in Antiplatelet Therapy for Atherosclerotic Vascular Disease: A Systematic Review

CNS Neuroscience &Therapeutics, Volume 31, Issue 2, February 2025.
Antiplatelet drugs are essential for treating atherosclerotic vascular disease (ASVD), but drug interactions can lead to resistance and affect therapeutic efficacy. Due to the complexity of treatments in ASVD patients, understanding these interactions is critical for optimizing therapy and reducing adverse effects.
Xiangqian Huang, Jiahao Song, Xiaoming Zhang, Mengqi Wang, Yuchuan Ding, Xunming Ji, Da Zhou, Ran Meng   +7 more
wiley   +1 more source

High‐dose IVIG plus cangrelor platelet “anesthesia” during urgent heparin‐CPB in a patient with recent SRA‐negative HIT‐thrombosis with persisting platelet‐activating antibodies

Research and Practice in Thrombosis and Haemostasis, 2020
In a high‐risk patient with subacute heparin‐induced thrombocytopenia (HIT) type A (platelet count recovery following acute HIT but with persisting platelet‐activating antibodies), in whom urgent cardiac surgery was required, a key clinical question ...
Andreas Koster, Ishac Nazy, Ingvild E. Birschmann, James W. Smith, Jo‐Ann I. Sheppard, Theodore E. Warkentin   +5 more
doaj   +1 more source

Are BVS suitable for ACS patients? Support from a large single center real live registry [PDF]

, 2016
Objectives To investigate one-year outcomes after implantation of a bioresorbable vascular scaffold (BVS) in patients presenting with acute coronary syndrome (ACS) compared to stable angina patients.
Daemen, J. (Joost), Diletti, R. (Roberto), Everaert, B. (Bert), Fam, J.M. (Jiang Ming), Felix, C.M. (Cordula), Geuns, R.J.M. (Robert Jan) van, Ishibashi, Y. (Yuki), Jaegere, P.P.T. (Peter) de, Karanasos, A. (Antonios), Mieghem, N.M. (Nicolas) van, Onuma, Y. (Yoshinobu), Regar, E.S. (Eveline), Zijlstra, F. (Felix)   +12 more
core   +1 more source

Therapeutic Potential of Gasdermin D‐Mediated Myocardial Pyroptosis in Ischaemic Heart Disease: Expanding the Paradigm From Bench to Clinical Insights

Journal of Cellular and Molecular Medicine, Volume 29, Issue 3, February 2025.
ABSTRACT Ischaemic heart disease (IHD) remains a leading cause of global morbidity and mortality. One significant contributor to the pathology of IHD is the excessive release of inflammatory mediators during the disease progression. Pyroptosis is a form of programmed cell death (PCD) triggered by the activation of inflammasomes and caspase 1.
Chanon Piamsiri, Chayodom Maneechote, Siriporn C. Chattipakorn, Nipon Chattipakorn   +3 more
wiley   +1 more source

Spanish Registry of Pressure‐Controlled Intermittent Coronary Sinus Occlusion (PiCSO) Balloon: Initial Experience and Short‐Term Clinical Outcomes

Journal of Interventional Cardiology, Volume 2025, Issue 1, 2025.
Objectives: The mortality of ST elevation myocardial infarction (STEMI) has plateaued in the last decade, with a 30‐day mortality of 3%‐4%. Previous studies in patients with anterior STEMI treated by primary angioplasty and assisted with the pressure‐controlled intermittent coronary sinus occlusion (PiCSO) system have shown a modest but significant ...
Erick Dante Martínez Maldonado, Victor Alfonso Jiménez Díaz, Guillermo Bastos Fernández, Pablo Vidal Calés, Salvatore Brugaletta, Pablo Juan Salvadores, Andrés Íñiguez Romo, Stefano Rigattieri   +7 more
wiley   +1 more source