Results 41 to 50 of about 160,881 (183)

Adenovirus and its interaction with host cell proteins [PDF]

open access: yes, 2007
The E1B55k gene in adenovirus type 5 was studied by generating recombinant viruses in which the E1B55k gene was N-terminally tagged with either a cyan fluorescent protein (CFP) tag or a tandem affinity purification (TAP) tag.
Carr, Sharon
core   +2 more sources

Systemic cellular viroimmunotherapy for canine high-grade gliomas

open access: yesJournal for ImmunoTherapy of Cancer, 2022
Background Oncolytic viruses constitute a growing field of interest, both in human and veterinary oncology, given that they are particularly helpful for treating non-surgical tumors and disseminated cancer, such as high-grade gliomas.
Ramon Alemany   +6 more
doaj   +1 more source

Adenovirus-based gene therapy approaches for hemophilia B [PDF]

open access: yes, 2012
Gene therapy can be used to treat devastating inherited diseases, especially diseases and patients that are not suitable for a conventional cure. The blood clotting disorder hemophilia is one of the most extensively studied monogenetic diseases in gene ...
Zhang, Wenli
core   +1 more source

Oncolytic virotherapy in veterinary medicine: current status and future prospects for canine patients

open access: yesJournal of Translational Medicine, 2012
Oncolytic viruses refer to those that are able to eliminate malignancies by direct targeting and lysis of cancer cells, leaving non-cancerous tissues unharmed.
Patil Sandeep S   +4 more
doaj   +1 more source

Detection of Selected Canine Viruses in Nigerian Free-Ranging Dogs Traded for Meat Consumption

open access: yesAnimals, 2023
Animal trade favors the spreading of emerging and re-emerging pathogens. Concerns have been previously expressed regarding the risks of dog trade in spreading zoonotic pathogens in Nigeria.
Linda A. Ndiana   +11 more
doaj   +1 more source

Safety and Efficacy of an Oncolytic Adenovirus as an Immunotherapy for Canine Cancer Patients

open access: yesVeterinary Sciences, 2022
The use of oncolytic viruses is an innovative approach to lyse tumor cells and induce antitumor immune responses. Eight dogs diagnosed with carcinoma/adenocarcinoma were intratumorally treated with ICOCAV15, an oncolytic canine adenovirus (CAV).
Clara Martín-Carrasco   +8 more
doaj   +1 more source

Transforming Genes of Canine Adenovirus Type 2

open access: yesJournal of General Virology, 1988
Genes of canine adenovirus type 2 (CAd2) involved in transformation were localized and their functions investigated. Cells transformed by CAd2 whole DNA or the BamHI A fragment (leftmost 47%) totally lacked contact inhibition and were serum-independent, anchorage-independent and tumorigenic in newborn rats. All the cells transformed by the XbaI D (0 to
T, Tsukiyama   +3 more
openaire   +2 more sources

Tumor-Homing of Mesenchymal Stem Cells Infected with Oncolytic Virus in a Canine Patient

open access: yesVeterinary Sciences, 2022
Intravenous administration of oncolytic adenovirus (OAds) can be challenging, although various vehicles for the delivery of the virus to the tumor have been described.
Pablo Delgado-Bonet   +3 more
doaj   +1 more source

Effect of Canine Adenovirus on JINET and Vero Cells

open access: yesThe Japanese Journal of Veterinary Science, 1977
Two simian cell lines, JINET and vero, were inoculated with infectiouscanine hepatitis virus at a variety of input multiplicity. The viral effects observed onthem were compared with those on primary dog kidney cells. Infected cell cultures andrecovered viruses were subjected to serial passages.In JINET cells, virus titer remained constant without ...
MURAKAMI, Toshiaki   +2 more
openaire   +3 more sources

Effect of immunization with fetal cells on adenovirus-12 oncogenesis [PDF]

open access: yes, 1974
The effect of immunization with hamster fetal cells on the tumor induction by adnovirus type 12 was studied by in vivo and in vitro. The immunization with lO-day old fetal cells showed a recognizable inhibition on the tumor induction by adenovirus type ...
Abe, Shinji
core   +1 more source

Home - About - Disclaimer - Privacy