Results 41 to 50 of about 8,456 (151)

Safety and Efficacy of an Oncolytic Adenovirus as an Immunotherapy for Canine Cancer Patients

open access: yesVeterinary Sciences, 2022
The use of oncolytic viruses is an innovative approach to lyse tumor cells and induce antitumor immune responses. Eight dogs diagnosed with carcinoma/adenocarcinoma were intratumorally treated with ICOCAV15, an oncolytic canine adenovirus (CAV).
Clara Martín-Carrasco   +8 more
doaj   +1 more source

Tumor-Homing of Mesenchymal Stem Cells Infected with Oncolytic Virus in a Canine Patient

open access: yesVeterinary Sciences, 2022
Intravenous administration of oncolytic adenovirus (OAds) can be challenging, although various vehicles for the delivery of the virus to the tumor have been described.
Pablo Delgado-Bonet   +3 more
doaj   +1 more source

Development and Validation of a Panel of One-Step Four-Plex qPCR/RT-qPCR Assays for Simultaneous Detection of SARS-CoV-2 and Other Pathogens Associated with Canine Infectious Respiratory Disease Complex

open access: yesViruses, 2023
Canine infectious respiratory disease complex (CIRDC) is the primary cause of respiratory disease in the canine population and is caused by a wide array of viruses and bacterial pathogens with coinfections being common. Since its recognition in late 2019,
Côme J. Thieulent   +5 more
doaj   +1 more source

Validation of a real-time PCR panel for detection and quantification of nine pathogens commonly associated with canine infectious respiratory disease

open access: yesMethodsX, 2023
Canine infectious respiratory disease (CIRD) is a complicated respiratory syndrome in dogs [1–3]. A panel PCR was developed [4] to detect nine pathogens commonly associated with CIRD: Mycoplasma cynos, Mycoplasma canis, Bordetella bronchiseptica; canine ...
Junsheng Dong   +15 more
doaj   +1 more source

Effect of Canine Adenovirus on JINET and Vero Cells

open access: yesThe Japanese Journal of Veterinary Science, 1977
Two simian cell lines, JINET and vero, were inoculated with infectiouscanine hepatitis virus at a variety of input multiplicity. The viral effects observed onthem were compared with those on primary dog kidney cells. Infected cell cultures andrecovered viruses were subjected to serial passages.In JINET cells, virus titer remained constant without ...
MURAKAMI, Toshiaki   +2 more
openaire   +3 more sources

Transforming Genes of Canine Adenovirus Type 2

open access: yesJournal of General Virology, 1988
Genes of canine adenovirus type 2 (CAd2) involved in transformation were localized and their functions investigated. Cells transformed by CAd2 whole DNA or the BamHI A fragment (leftmost 47%) totally lacked contact inhibition and were serum-independent, anchorage-independent and tumorigenic in newborn rats. All the cells transformed by the XbaI D (0 to
T, Tsukiyama   +3 more
openaire   +2 more sources

Proteomic Remodeling in the Failing Left Ventricle Adapting to Dyssynchrony

open access: yesPROTEOMICS – Clinical Applications, Volume 20, Issue 5, September 2026.
ABSTRACT Purpose In heart failure, dyssynchrony is associated with accelerated cardiac remodeling and a worse prognosis. Both restored with resynchronization. We have previously developed a mouse model of dyssynchrony and resynchronization and here assess changes in protein expression within that model.
Karin Ljung   +4 more
wiley   +1 more source

Predominance of Canine Parainfluenza Virus and Mycoplasma in Canine Infectious Respiratory Disease Complex in Dogs

open access: yesPathogens, 2023
Canine infectious respiratory disease complex (CIRDC) is caused by different viruses and bacteria. Viruses associated with CIRDC include canine adenovirus type 2 (CAV-2), canine distemper virus (CDV), canine influenza virus (CIV), canine herpesvirus type
Aurelle Yondo   +5 more
doaj   +1 more source

Deep Mutational Scanning for the Study and Engineering of Protein Assemblies

open access: yesChemistry–Methods, Volume 6, Issue 8, August 2026.
This review explores how deep mutational scanning (DMS) can be used to improve understanding and accelerate engineering of protein assemblies, from natural fibers to engineered nanocages. We discuss various types of protein assemblies and their characterization, provide an introduction to the DMS technique, and then highlight examples in which DMS has ...
Jenna B. Wolfanger   +2 more
wiley   +1 more source

Canine infectious respiratory disease: New insights into the etiology and epidemiology of associated pathogens.

open access: yesPLoS ONE, 2019
Canine infectious respiratory disease (CIRD) is a syndrome where multiple viral and bacterial pathogens are involved sequentially or synergistically to cause illness.
Grazieli Maboni   +4 more
doaj   +1 more source

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