Results 41 to 50 of about 160,881 (183)
Adenovirus and its interaction with host cell proteins [PDF]
The E1B55k gene in adenovirus type 5 was studied by generating recombinant viruses in which the E1B55k gene was N-terminally tagged with either a cyan fluorescent protein (CFP) tag or a tandem affinity purification (TAP) tag.
Carr, Sharon
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Systemic cellular viroimmunotherapy for canine high-grade gliomas
Background Oncolytic viruses constitute a growing field of interest, both in human and veterinary oncology, given that they are particularly helpful for treating non-surgical tumors and disseminated cancer, such as high-grade gliomas.
Ramon Alemany +6 more
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Adenovirus-based gene therapy approaches for hemophilia B [PDF]
Gene therapy can be used to treat devastating inherited diseases, especially diseases and patients that are not suitable for a conventional cure. The blood clotting disorder hemophilia is one of the most extensively studied monogenetic diseases in gene ...
Zhang, Wenli
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Oncolytic viruses refer to those that are able to eliminate malignancies by direct targeting and lysis of cancer cells, leaving non-cancerous tissues unharmed.
Patil Sandeep S +4 more
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Detection of Selected Canine Viruses in Nigerian Free-Ranging Dogs Traded for Meat Consumption
Animal trade favors the spreading of emerging and re-emerging pathogens. Concerns have been previously expressed regarding the risks of dog trade in spreading zoonotic pathogens in Nigeria.
Linda A. Ndiana +11 more
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Safety and Efficacy of an Oncolytic Adenovirus as an Immunotherapy for Canine Cancer Patients
The use of oncolytic viruses is an innovative approach to lyse tumor cells and induce antitumor immune responses. Eight dogs diagnosed with carcinoma/adenocarcinoma were intratumorally treated with ICOCAV15, an oncolytic canine adenovirus (CAV).
Clara Martín-Carrasco +8 more
doaj +1 more source
Transforming Genes of Canine Adenovirus Type 2
Genes of canine adenovirus type 2 (CAd2) involved in transformation were localized and their functions investigated. Cells transformed by CAd2 whole DNA or the BamHI A fragment (leftmost 47%) totally lacked contact inhibition and were serum-independent, anchorage-independent and tumorigenic in newborn rats. All the cells transformed by the XbaI D (0 to
T, Tsukiyama +3 more
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Tumor-Homing of Mesenchymal Stem Cells Infected with Oncolytic Virus in a Canine Patient
Intravenous administration of oncolytic adenovirus (OAds) can be challenging, although various vehicles for the delivery of the virus to the tumor have been described.
Pablo Delgado-Bonet +3 more
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Effect of Canine Adenovirus on JINET and Vero Cells
Two simian cell lines, JINET and vero, were inoculated with infectiouscanine hepatitis virus at a variety of input multiplicity. The viral effects observed onthem were compared with those on primary dog kidney cells. Infected cell cultures andrecovered viruses were subjected to serial passages.In JINET cells, virus titer remained constant without ...
MURAKAMI, Toshiaki +2 more
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Effect of immunization with fetal cells on adenovirus-12 oncogenesis [PDF]
The effect of immunization with hamster fetal cells on the tumor induction by adnovirus type 12 was studied by in vivo and in vitro. The immunization with lO-day old fetal cells showed a recognizable inhibition on the tumor induction by adenovirus type ...
Abe, Shinji
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