Results 31 to 40 of about 160,881 (183)
Canine Adenovirus Vectors: an Alternative for Adenovirus-Mediated Gene Transfer [PDF]
Journal of Virology, 2000 ABSTRACTPreclinical studies have shown that gene transfer following readministration of viral vectors is often inefficient due to the presence of neutralizing antibodies. Vectors derived from ubiquitous human adenoviruses may have limited clinical use because preexisting humoral and cellular immunity is found in 90% of the population.
E J, Kremer +3 more
openaire +2 more sources
Molecular Therapy: Oncolytics, 2020 Oncolytic immunotherapy with competent viruses is an emerging approach in cancer treatment. The clinical safety of many types of oncolytic viruses (OVs) has been demonstrated.
Ana Gómez +5 more
doaj +1 more source
Aetiopathology of canine hepatitis in Kerala [PDF]
Journal of Veterinary and Animal Sciences, 2023 Hepatitis in dogs could be due to infectious, toxic or metabolic causes. Among infectious causes, leptospira, canine adenovirus (CAV 1) and babesia are responsible at varying levels, depending on the local geo-climatic conditions. This study, conducted
Alphiya Joseph +4 more
doaj +1 more source
Altering the Ad5 packaging domain affects the maturation of the Ad particles [PDF]
, 2011 We have previously described a new family of mutant adenoviruses carrying different combinations of attB/attP sequences from bacteriophage PhiC31 flanking the Ad5 packaging domain.
Alba Fernández, Raúl +23 more
core +2 more sources
Macromolecular Content of Inclusions Produced by a Canine Adenovirus [PDF]
Journal of Virology, 1972 Early inclusions induced by a canine adenovirus in a canine cell line, appearing before the formation of infectious virus particles, were purified by differential centrifugation in sucrose followed by CsCl density gradient centrifugation.
M S, Shahrabadi, K L, Roy, T, Yamamoto
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Brain tumors induced in rats by human adenovirus type 12 [PDF]
, 1974 Oncogenesis of human adenovirus type 12 in the brain of rats was examined. Newborn rats of Sprague-Dawley and Donryu strains were injected intracranially with human adenovirus type 12. The incidence of intracranial tumors was 91% (30/33) in
Ogawa, Katsuo +5 more
core +1 more source
Canine adenovirus type 2 vector generation via I-Sce1-mediated intracellular genome release. [PDF]
PLoS ONE, 2013 When canine adenovirus type 2 (CAdV-2, or also commonly referred to as CAV-2) vectors are injected into the brain parenchyma they preferentially transduce neurons, are capable of efficient axonal transport to afferent regions, and allow transgene ...
Sandy Ibanes, Eric J Kremer
doaj +1 more source
Morphological Studies of a Canine Adenovirus
Journal of General Virology, 1968 A strain of virus (a 26/61) isolated by Ditchfield, Macpherson & Zbitnew (1962) from dogs ill with infectious laryngotracheitis was shown to be a canine adenovirus serologically related to infectious canine hepatitis virus. Further studies (Yamamoto, 1966) showed this infectious laryngotracheitis virus to be similar to other adenoviruses with respect ...
T, Yamamoto, R G, Maruysk
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Determining new functions of Adenovirus VA-RNAI and its use in cancer therapy [PDF]
, 2009 PhDVirus-Associated RNA I (VA-RNAI; VAI) of adenovirus is a nontranslated RNA molecule known to interact with several dsRNA-binding molecules in host cells.
Binny, Christopher Jonathan
core +4 more sources
Canine Hepatitis Virus and Human Adenovirus [PDF]
Public Health Reports (1896-1970), 1962 INCREASING awareness of human infectious hepatitis and the common occurrence of infectious canine hepatitis in the United States have precipitated queries about the possible transmission of the canine disease to man, particularly when illness occurs simultaneously or has similar manifestations in a pet and in a family member.
openaire +2 more sources