Results 61 to 70 of about 29,808,159 (189)

Clinical outcome, imaging and histopathological findings of liver cirrhosis in dogs

Veterinary Record Case Reports, Volume 14, Issue 3, August 2026.
Abstract Cirrhosis is a severe and irreversible condition resulting from chronic liver injury, characterised by extensive fibrosis and regenerative nodules. This report describes three dogs with cirrhosis. The main clinical findings included ascites, reduced body condition score and inappetence. Anaemia, thrombocytopenia, hypoalbuminaemia, and elevated
Wanderson Feliciano Duarte da Silva, Roger Fernando Neves da Silva, Edson Moleta Colodel, Pedro Eduardo Brandini Nespóli, Valeria Regia Franco Sousa   +4 more
wiley   +1 more source

Chicken adenovirus (CELO virus) particles augment receptor-mediated DNA delivery to mammalian cells and yield exceptional levels of stable transformants. [PDF]

, 1993
Delivery of genes via receptor-mediated endocytosis is severely limited by the poor exit of endocytosed DNA from the endosome. A large enhancement in delivery efficiency has been obtained by including human adenovirus particles in the delivery system ...
Malt Cotlen, Kurt Zatloukal, Max, Wagner, E., L. Birnstiel, Wagner, Ernst, Birnstiel, Max L., Ernst Wagner, Cotten, Matt, Zatloukal, Kurt, Cotten, M., Zatloukal, K., Birnstiel, M.L.   +12 more
core  

A serological survey of infectious disease in Yellowstone National Park's canid community. [PDF]

PLoS ONE, 2009
BACKGROUND:Gray wolves (Canis lupus) were reintroduced into Yellowstone National Park (YNP) after a >70 year absence, and as part of recovery efforts, the population has been closely monitored.
Emily S Almberg, L David Mech, Douglas W Smith, Jennifer W Sheldon, Robert L Crabtree   +4 more
doaj   +1 more source

Exposure of wild Caspian seals (Pusa caspica) to parasites, bacterial and viral pathogens, evaluated via molecular and serological assays

Frontiers in Marine Science, 2023
Disease surveillance of marine mammal populations is essential to understand the causes of strandings, identify potential threats to animal health, and to support development of conservation strategies.
Aidyn Kydyrmanov, Kobey Karamendin, Yermukhammet Kassymbekov, Marat Kumar, Shynar Mazkirat, Symbat Suleimenova, Mirgaliy Baimukanov, Ian M. Carr, Simon J. Goodman   +8 more
doaj   +1 more source

Ca2+‐Activated Cl− Channels: Do Bestrophins and TMEM16A Interact?

Acta Physiologica, Volume 242, Issue 6, June 2026.
ABSTRACT Aim Ca2+‐activated Cl– conductances are present in many cell types and are important for regulating membrane potential as well as other cellular functions. TMEM16A is widely accepted as the principal molecular basis for Ca2+‐activated Cl– conductances, but also members of the bestrophin family may be important for some Ca2+‐activated Cl ...
Christian Aalkjær, Vibeke Secher Dam, Holger Nilsson, Donna B. Boedtkjer, Vladimir Matchkov   +4 more
wiley   +1 more source

Canine distemper virus and canine adenovirus type 1 co-infection in a free-living hoary fox (Lycalopex vetulus) from Brazil

Brazilian Journal of Microbiology, 2023
The present case is the first description of a co-infection with canine distemper virus (CDV) and canine adenovirus type 1 (CAdV-1) in a free-living hoary fox pup from Brazil. The animal was found and rescued with poor body condition, dehydration, incoordination, ataxia, excessive vocalization, and "blue eyes" phenomenon.
Maraya Lincoln Silva, Mayara Grego Caiaffa, André Luiz Mota da Costa, Rodrigo Hidalgo Friciello Teixeira, Ticiana Brasil Ervedosa, Eduardo Ferreira Machado, Pedro Enrique Navas Suárez, Rodrigo Albergaria Réssio, Cinthya Cirqueira Borges, Isis Paixão de Jesus, Julia de Carvalho, Ketlyn Bolsachini Figueiredo, Ana Carolina Souza Ramos de Carvalho, Paulo Eduardo Brandão, Natália Coelho Couto de Azevedo Fernandes, Juliana Mariotti Guerra   +15 more
openaire   +4 more sources

Carrier cell-mediated cell lysis of squamous cell carcinoma by squamous cell carcinoma antigen 1 promoter-driven oncolytic adenovirus [PDF]

, 2009
The squamous cell carcinoma antigen (SCCA) serves as a serological marker for squamous cell carcinomas. Molecular cloning of the SCCA genomic region has revealed the presence of two tandemly arrayed genes, SCCA1 and SCCA2.
Yoshiyuki Koyama, Hiroyuki Hamakawa, Hiroshi Ito, Kenzaburo Tani, Junzo Desaki, Ting Zhang, Katsuyuki Hamada, Koh-ichi Nakashiro   +7 more
core  

Assessment and development of adenovirus type 11 for cancer therapy [PDF]

, 2010
PhDThe efficacy of oncolytic virotherapy is influenced by the interactions between the tumour, virus and host immunity. The first generation of oncolytic adenoviruses, based on serotype 5 (Ad5), has achieved limited success in clinical trials.
Wong, Han Hsi
core   +4 more sources

Emerging Roles of Adenosine Metabolism in Astrocytes During Brain Injury

CNS Neuroscience &Therapeutics, Volume 32, Issue 5, May 2026.
Adenosine, as a key metabolic and neurotransmitter in the brain, has become an important therapeutic target for improving the efficacy of immunotherapy for stroke. However, gaps in knowledge about its metabolic pathways have become a key factor limiting its clinical translation.
Shu Zhu, Shanshan Zhong, Xiaoru Lin, Chuansheng Zhao, Yugang Li   +4 more
wiley   +1 more source

Advances in Gene Therapy for Xerostomia: Current Perspectives and Future Directions: A Narrative Review

Health Science Reports, Volume 9, Issue 5, May 2026.
ABSTRACT Background and Aims Xerostomia, or dry mouth, significantly impairs quality of life and oral health, particularly in patients subjected to radiation therapy or suffering from systemic disorders. This narrative review summarizes the current evidence on the efficacy and safety of gene therapy interventions for xerostomia, exploring innovative ...
Muhammad Usman Bilal, Sarah Alvi, Fatima Humayune, Hasan Mujtaba, Shahzad Ahmad, Shazia Iqbal, Muhammad Farooq Umer   +6 more
wiley   +1 more source