Results 71 to 80 of about 29,808,159 (189)

YB-1 dependent oncolytic adenovirus efficiently inhibits tumor growth of glioma cancer stem like cells [PDF]

, 2013
Background: The brain cancer stem cell (CSC) model describes a small subset of glioma cells as being responsible for tumor initiation, conferring therapy resistance and tumor recurrence.
Mittelbronn, Michel Guy André, Janina Seznec, Michel Mittelbronn, Jürgen Schlegel, Surowiak, Pawel, Ulrike Naumann, Klaus Mantwill, Naumann, Ulrike, Vroni Girbinger, Per Holm, Dagmar Beier, Girbinger, Vroni, Lage, Hermann, Holm, Per Sonne, Pawel Surowiak, Hermann Lage, Schlegel, Jürgen, Beier, Dagmar, Seznec, Janina, Mantwill, Klaus   +19 more
core   +1 more source

DIAGNOSTIC BIOMARKERS OF INFECTIOUS CANINE HEPATITIS IN EXPERIMENTALLY INFECTED PUPPIES [PDF]

Kafrelsheikh Veterinary Medical Journal, 2012
Infectious canine hepatitis (ICH) is a systemic disease of Canidae and Ursidae caused by canine adenovirus type 1 (CAV-1) produces acute necrohemorrhagic hepatitis.
Abdalla Moukhbtly, Khaled Kahilo, Naglaa Fouad, Mahmoud S. El-Neweshy, Samy Kasem   +4 more
doaj   +1 more source

Ischaemic dermatopathy associated with multiple vaccinations in a miniature poodle

Veterinary Record Case Reports, Volume 14, Issue 2, May 2026.
Abstract A 10‐year‐old, spayed, female miniature poodle presented with hyperpigmented alopecia. Two months prior, it had received two polyvalent vaccines 2 weeks apart. Erythematous alopecia at the injection sites was initially observed. These rapidly expanded to the ventral neck and thoracic regions after further rabies vaccination.
Daekyung Kim, Sang‐Ik Oh, Jinho Park, Ji‐Seon Yoon   +3 more
wiley   +1 more source

Two distinctive transforming DNA regions on the canine adenovirus type 1 genome.

Japanese journal of cancer research : Gann, 1985
By transfecting cloned DNA fragments of canine adenovirus type 1, a novel transforming region of mammalian adenovirus was demonstrated inside the viral genome. Besides the left-end SmaI-D fragment (left 17.2%), an internally located SmaI-E fragment (17.2-28.7%) of canine adenovirus type 1 was found to transform primary rat kidney cells.
YAMASHITA, Toshiharu, REN, Chang Shan, YOSHIDA, Kouichi, SHINAGAWA, Morikazu, MASUDA, Ken-ichi, FUJINAGA, Kei   +5 more
openaire   +2 more sources

The human adenovirus 5 L4 promoter is activated by cellular stress response protein p53 [PDF]

, 2013
During adenovirus infection, the emphasis of gene expression switches from early genes to late genes in a highly regulated manner. Two gene products, L4-22K and L4-33K, contribute to this switch by activating the Major Late Transcription Unit (MLTU) and ...
Leppard, Keith, Wright, Jordan
core   +1 more source

Canine chronic idiopathic rhinitis: management and outcome – a single‐centre retrospective observational study

Journal of Small Animal Practice, Volume 67, Issue 5, Page 460-470, May 2026.
Objectives Canine chronic idiopathic rhinitis is a common cause of nasal disease in dogs but data reporting outcomes following treatment is lacking. The aim was to describe pre‐ and post‐referral management and outcomes of dogs diagnosed with canine chronic idiopathic rhinitis at a single referral centre.
P. M. N. Henry, R. Rizzo, Y. Tan, A. M. Boag, J. Del‐Pozo, G. A. Woods   +5 more
wiley   +1 more source

Visceral leishmaniasis and infectious hepatitis in bush dog from captivity in Brazil - Report of case/
Leishmaniose visceral e hepatite infecciosa em cachorro-vinagre mantido em cativeiro no Brasil - Relato de Caso

Semina: Ciências Agrárias, 2011
Among mammals, the canids are most often infected by Leishmania sp. This paper reports the occurrence of Leishmania (Leishmania) infantum chagasi as well as the presence of intranuclear inclusions resembling viral particles of canine adenovirus-1 in a ...
Luciano Nakazato, Valéria Dutra, Edson Moleta Colodel, Daphine Ariadne Jesus de Paula, Arleana Bom Parto Ferreira de Almeida, Valéria Régia Franco Sousa   +5 more
doaj   +1 more source

Connexin43 Deficiency Leads to Ventricular Arrhythmias by Reprogramming Proline Metabolism

Advanced Science, Volume 13, Issue 19, 2 April 2026.
The study demonstrated that connexin43 (Cx43) knockout caused arrhythmic phenotype and decreased proline content in vitro and in vivo. Mechanistically, Cx43 interacts with the amino acid transporter SNAT2 (sodium‐dependent neutral amino acid transporter), and its deficiency disrupts proline transport and metabolism.
Hangying Ying, Hangping Fan, Yunhe Wang, Ruhong Jiang, Dongsheng Cai, Hui Cheng, Hao Wang, Chenyang Jiang, Ping Liang   +8 more
wiley   +1 more source

Modification of the E1-pIX region of the adenovirus 5 genome for use in cancer gene therapy [PDF]

, 2008
Currently the use of adenoviruses in cancer gene therapy is limited by efficient delivery of the virus into the tumour cells, detargeting of the virus from the liver, and the efficient spread of the virus within the tumour.
Kallioinen, Susanna E.
core   +2 more sources

Safeguarding a Flagship Species: Integrated Surveillance of Cross‐Species Pathogen Transmission in Giant Panda Ecosystems

Ecology and Evolution, Volume 16, Issue 3, March 2026.
Emerging infectious diseases increasingly threaten giant pandas and cohabiting species. This review analyzes pathogen transmission risks from domestic animals, wildlife, and vectors and proposes an integrated genomic surveillance framework for early warning and biodiversity conservation.
Xiaoli Sun, Yi Peng, Xiaoye Hao, Rong Dong, Zhilin Wang, Le Wang, Chengdong Wang, Xiangdong Wu, Zheng Chen, Wenbo Zhang, Xiaoli Tang   +10 more
wiley   +1 more source