Results 41 to 50 of about 7,626 (147)
The apicomplexan parasite Toxoplasma gondii, the causative agent of toxoplasmosis, can infect all warm-blooded animals. T. gondii can subtly alter host behaviors—either through manipulation to enhance transmission to the feline definitive host or as a ...
Gregory Milne +17 more
doaj +1 more source
Emerging Roles of Adenosine Metabolism in Astrocytes During Brain Injury
Adenosine, as a key metabolic and neurotransmitter in the brain, has become an important therapeutic target for improving the efficacy of immunotherapy for stroke. However, gaps in knowledge about its metabolic pathways have become a key factor limiting its clinical translation.
Shu Zhu +4 more
wiley +1 more source
Ischaemic dermatopathy associated with multiple vaccinations in a miniature poodle
Abstract A 10‐year‐old, spayed, female miniature poodle presented with hyperpigmented alopecia. Two months prior, it had received two polyvalent vaccines 2 weeks apart. Erythematous alopecia at the injection sites was initially observed. These rapidly expanded to the ventral neck and thoracic regions after further rabies vaccination.
Daekyung Kim +3 more
wiley +1 more source
Objectives Canine chronic idiopathic rhinitis is a common cause of nasal disease in dogs but data reporting outcomes following treatment is lacking. The aim was to describe pre‐ and post‐referral management and outcomes of dogs diagnosed with canine chronic idiopathic rhinitis at a single referral centre.
P. M. N. Henry +5 more
wiley +1 more source
CAV-2 Vector Development and Gene Transfer in the Central and Peripheral Nervous Systems
The options available for genetic modification of cells of the central nervous system (CNS) have greatly increased in the last decade. The current panoply of viral and nonviral vectors provides multifunctional platforms to deliver expression cassettes to
Danila del Rio +7 more
doaj +1 more source
Connexin43 Deficiency Leads to Ventricular Arrhythmias by Reprogramming Proline Metabolism
The study demonstrated that connexin43 (Cx43) knockout caused arrhythmic phenotype and decreased proline content in vitro and in vivo. Mechanistically, Cx43 interacts with the amino acid transporter SNAT2 (sodium‐dependent neutral amino acid transporter), and its deficiency disrupts proline transport and metabolism.
Hangying Ying +8 more
wiley +1 more source
Two distinctive transforming DNA regions on the canine adenovirus type 1 genome.
By transfecting cloned DNA fragments of canine adenovirus type 1, a novel transforming region of mammalian adenovirus was demonstrated inside the viral genome. Besides the left-end SmaI-D fragment (left 17.2%), an internally located SmaI-E fragment (17.2-28.7%) of canine adenovirus type 1 was found to transform primary rat kidney cells.
YAMASHITA, Toshiharu +5 more
openaire +2 more sources
Non‐Canonical Subiculum Circuit Organization and Function
ABSTRACT The subiculum is highly interconnected with the hippocampus, sub‐regions of the thalamus, and the entorhinal and retrosplenial cortices. Together, these regions form a distributed network that plays critical roles in spatial cognition and learning and memory.
Pan Gao +3 more
wiley +1 more source
Molecular Detection of Viral and Bacterial Pathogens in Red Foxes (Vulpes vulpes) from Italy
Animals, including wildlife, are part of One-Health concept since many infectious diseases can affect both humans and animals. In this study, 126 red foxes (Vulpes vulpes) from Northern Italy in 2022–2023 were tested by molecular assays for ...
Martina Magliocca +12 more
doaj +1 more source
Molecular detection of pathogens in an equine fever diagnostic panel: 2019–2023
Abstract Background A common diagnostic approach for febrile horses is to test for a panel of potential pathogens. Panels are curated by expert opinion and vary between diagnostic laboratories. Objectives To report the results of a newly developed equine fever diagnostic panel (EFDP) between 2019 and 2023 and evaluate the frequency of positive results.
Toby L. Pinn‐Woodcock +3 more
wiley +1 more source

