Results 51 to 60 of about 7,626 (147)

Gene therapy for epilepsy: An emerging, promising approach for a serious neurological disorder

Journal of Internal Medicine, Volume 299, Issue 3, Page 302-327, March 2026.
Abstract Gene therapy is emerging as a groundbreaking strategy for treating epilepsy, offering new hope to patients who do not respond to conventional medications. Despite advancements in anti‐seizure treatments, nearly 30%–40% of individuals with epilepsy continue to experience uncontrolled seizures, highlighting the urgent need for more effective and
Marco Ledri, Merab Kokaia
wiley   +1 more source

Cell and Gene Therapy in Equine Ocular Disease

Veterinary Ophthalmology, Volume 29, Issue 2, March 2026.
ABSTRACT Equine ocular disease is common and often challenging to treat using traditional methods. This has led to the development of new therapies. Like human medicine, veterinary medicine is adopting cellular and gene therapy as innovative approaches. Equine ocular disease is a particularly promising area for these techniques.
Kimberly A. S. Young, Lauren V. Schnabel, Brian C. Gilger   +2 more
wiley   +1 more source

Transduction of Craniofacial Motoneurons Following Intramuscular Injections of Canine Adenovirus Type-2 (CAV-2) in Rhesus Macaques

Frontiers in Neuroanatomy, 2019
Reliable viral vector-mediated transgene expression in primate motoneurons would improve our ability to anatomically and physiologically interrogate motor systems.
Martin O. Bohlen, Hala G. El-Nahal, Marc A. Sommer, Marc A. Sommer   +3 more
doaj   +1 more source

Characterising the Transcriptomic Response to Interferon and Infection in European Domestic Ferret Respiratory Tissues Using Long‐Read RNA Sequencing

Immunology, Volume 177, Issue 2, Page 299-316, February 2026.
We utilised long‐read Nanopore sequencing to characterise the transcriptome of ferret cell lines stimulated with IFN‐α as well as nasal turbinates from ferrets infected with influenza A virus. We identified novel genes and isoforms and observed elongation of poly(A) tails in the ribosome and Coronavirus Disease‐19 pathways in response to IFN‐α ...
Rubaiyea Farrukee, Jessie J.‐Y. Chang, Jianshu Zhang, James B. Barnes, Shu Xin Zhang, Sher Maine Tan, Patrick C. Reading, Lachlan J. M. Coin   +7 more
wiley   +1 more source

Bee products as alternatives in the treatment of viral infections

Journal of the Science of Food and Agriculture, Volume 106, Issue 1, Page 33-54, 15 January 2026.
Abstract Medicines used in the treatment of viral infections usually reduce symptoms. There is a need to develop drugs that inhibit the viruses and do not merely relieve the symptoms. Natural bee products possess many pharmacological properties and are widely used in folk medicine. There are many studies on the antibacterial effects of bee products but
Michał Otręba, Łukasz Marek, Jerzy Stojko, Anna Rzepecka‐Stojko   +3 more
wiley   +1 more source

Innovative Test Bench for Comprehensive Evaluation of Portable Air Cleaner Performance Against Infectious Human Respiratory Pathogens

Indoor Air, Volume 2026, Issue 1, 2026.
Background The COVID‐19 pandemic has underscored the critical role of indoor air quality and ventilation in the transmission of respiratory viruses. Although portable air cleaners (PACs) have proliferated in recent years, most performance evaluations rely on indirect measurement approaches or surrogate microorganisms, leaving uncertainty regarding ...
Jessica Morel, Clément Droillard, Jean-Michel Lenoir, Camille Ménard, Samuel Le Hir, Emma Ensenat, Clara Bourgeay, Tiago Zambujo, Anaïs Proust, Thomas Julien, Manuel Rosa-Calatrava, Fèlix Faming Wang   +11 more
wiley   +1 more source

Recent Advances in Lateral Flow Immunoassay for Rapid Diagnosis of Viral Diseases

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Viral diseases are a major threat to human and animal health, as illustrated by recent pandemics like COVID‐19 and African swine fever (ASF). Timely, accurate detection of viral infections is critical for effective disease control. Among diverse diagnostic techniques, lateral flow immunoassay (LFIA) has become a widely used on‐site testing tool, owing ...
Quanyu Ren, Yan Wang, Haoyuan Ma, Jialiang Xie, Jianyou Jin, Rumeng Tian, Hao Yu, Xu Gao, Nanhua Chen   +8 more
wiley   +1 more source

Awareness of Microbiological Safety in Playgrounds Amid Rising Antibiotic Resistance

Environmental Microbiology Reports, Volume 17, Issue 6, December 2025.
Playgrounds are identified as reservoirs for antibiotic‐resistant bacteria, posing a potential public health risk. Despite the existence of safety regulations for playground equipment, microbiological safety is treated superficially. Global strategies, including hygiene practices and antibacterial materials, are needed to reduce the spread of ...
Rafał Łopucki, Marcin Skowronek, Anna Bilokinna, Guillermo Martinez‐de‐Tejada, Ilona Sadok   +4 more
wiley   +1 more source

Detection of pathogens in dogs with respiratory disease during winter 2023–2024 using multiplex qPCR/RT-qPCR assays and next-generation sequencing

Frontiers in Veterinary Science
Canine Infectious Respiratory Disease Complex (CIRDC), caused by a diverse range of viral and bacterial pathogens, is the leading cause of respiratory illness in dogs.
Côme J. Thieulent, Melissa Laverack, Mariano Carossino, Mariano Carossino, Brittany Cronk, Leonardo Cardia Caserta, Diego G. Diel, Udeni B. R. Balasuriya   +7 more
doaj   +1 more source

The European Union One Health 2024 Zoonoses Report

EFSA Journal, Volume 23, Issue 12, December 2025.
Abstract This report by the European Food Safety Authority and the European Centre for Disease Prevention and Control presents the results of zoonoses monitoring and surveillance activities carried out in 2024 in 27 Member States (MSs), the United Kingdom (Northern Ireland) and eight non‐MSs, according to the Zoonoses Directive 2003/99/EC.
European Food Safety Authority (EFSA) | European Centre for Disease Prevention and Control (ECDC)
wiley   +1 more source