Results 71 to 80 of about 34,545,473 (172)

Transduction of Craniofacial Motoneurons Following Intramuscular Injections of Canine Adenovirus Type-2 (CAV-2) in Rhesus Macaques

open access: yesFrontiers in Neuroanatomy, 2019
Reliable viral vector-mediated transgene expression in primate motoneurons would improve our ability to anatomically and physiologically interrogate motor systems.
Martin O. Bohlen   +3 more
doaj   +1 more source

Safeguarding a Flagship Species: Integrated Surveillance of Cross‐Species Pathogen Transmission in Giant Panda Ecosystems

open access: yesEcology and Evolution, Volume 16, Issue 3, March 2026.
Emerging infectious diseases increasingly threaten giant pandas and cohabiting species. This review analyzes pathogen transmission risks from domestic animals, wildlife, and vectors and proposes an integrated genomic surveillance framework for early warning and biodiversity conservation.
Xiaoli Sun   +10 more
wiley   +1 more source

Determining new functions of Adenovirus VA-RNAI and its use in cancer therapy [PDF]

open access: yes, 2009
PhDVirus-Associated RNA I (VA-RNAI; VAI) of adenovirus is a nontranslated RNA molecule known to interact with several dsRNA-binding molecules in host cells.
Binny, Christopher Jonathan
core   +3 more sources

Non‐Canonical Subiculum Circuit Organization and Function

open access: yesHippocampus, Volume 36, Issue 2, March 2026.
ABSTRACT The subiculum is highly interconnected with the hippocampus, sub‐regions of the thalamus, and the entorhinal and retrosplenial cortices. Together, these regions form a distributed network that plays critical roles in spatial cognition and learning and memory.
Pan Gao   +3 more
wiley   +1 more source

Molecular detection of pathogens in an equine fever diagnostic panel: 2019–2023

open access: yesEquine Veterinary Journal, Volume 58, Issue 2, Page 486-496, March 2026.
Abstract Background A common diagnostic approach for febrile horses is to test for a panel of potential pathogens. Panels are curated by expert opinion and vary between diagnostic laboratories. Objectives To report the results of a newly developed equine fever diagnostic panel (EFDP) between 2019 and 2023 and evaluate the frequency of positive results.
Toby L. Pinn‐Woodcock   +3 more
wiley   +1 more source

Transductional retargeting of human adenovirus type 5 to ανβ6 integrin for cancer gene therapy [PDF]

open access: yes, 2009
PhDA key impediment to successful cancer therapy with adenoviral vectors is the inefficient transduction of malignant tissue in vivo. Compounding this problem is the lack of cancer-specific targets, coupled with a shortage of corresponding high ...
Coughlan, Lynda
core   +3 more sources

Detection of pathogens in dogs with respiratory disease during winter 2023–2024 using multiplex qPCR/RT-qPCR assays and next-generation sequencing

open access: yesFrontiers in Veterinary Science
Canine Infectious Respiratory Disease Complex (CIRDC), caused by a diverse range of viral and bacterial pathogens, is the leading cause of respiratory illness in dogs.
Côme J. Thieulent   +7 more
doaj   +1 more source

Gene therapy for epilepsy: An emerging, promising approach for a serious neurological disorder

open access: yesJournal of Internal Medicine, Volume 299, Issue 3, Page 302-327, March 2026.
Abstract Gene therapy is emerging as a groundbreaking strategy for treating epilepsy, offering new hope to patients who do not respond to conventional medications. Despite advancements in anti‐seizure treatments, nearly 30%–40% of individuals with epilepsy continue to experience uncontrolled seizures, highlighting the urgent need for more effective and
Marco Ledri, Merab Kokaia
wiley   +1 more source

Abstracts

open access: yesMolecular Oncology, Volume 20, Issue S1, Page 1-692, August 2026.
Abstracts submitted to the ‘EACR 2026 Congress: Innovative Cancer Science’, from 08–11 June 2026 and accepted by the Congress Organising Committee are published in this Supplement of Molecular Oncology, an affiliated journal of the European Association for Cancer Research (EACR).
wiley   +1 more source

Cell and Gene Therapy in Equine Ocular Disease

open access: yesVeterinary Ophthalmology, Volume 29, Issue 2, March 2026.
ABSTRACT Equine ocular disease is common and often challenging to treat using traditional methods. This has led to the development of new therapies. Like human medicine, veterinary medicine is adopting cellular and gene therapy as innovative approaches. Equine ocular disease is a particularly promising area for these techniques.
Kimberly A. S. Young   +2 more
wiley   +1 more source

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