Results 91 to 100 of about 18,590 (210)

Canine coronavirus infection in the dog following oronasal inoculation [PDF]

Research in Veterinary Science, 1991
The pathogenesis of canine coronavirus (CCV) infection in 10-week-old puppies was studied up to 14 days after oronasal inoculation. Mild diarrhoea was seen from three to 11 days after inoculation, approximately coincident with faecal virus shedding. Virus was initially isolated from the tonsils on day 3, and then from both small and large intestinal ...
Tennant, B.J., Gaskell, R.M., Kelly, D.F., Carter, S.D., Gaskell, C.J.   +4 more
openaire   +2 more sources

Molecular detection of pathogens in an equine fever diagnostic panel: 2019–2023

Equine Veterinary Journal, Volume 58, Issue 2, Page 486-496, March 2026.
Abstract Background A common diagnostic approach for febrile horses is to test for a panel of potential pathogens. Panels are curated by expert opinion and vary between diagnostic laboratories. Objectives To report the results of a newly developed equine fever diagnostic panel (EFDP) between 2019 and 2023 and evaluate the frequency of positive results.
Toby L. Pinn‐Woodcock, Melissa S. Aprea, Manigandan Lejeune, Joy E. Tomlinson   +3 more
wiley   +1 more source

SEROLOGIC SURVEY FOR CANINE CORONAVIRUS IN WOLVES FROM ALASKA [PDF]

Journal of Wildlife Diseases, 2001
Wolves (Canis lupus) were captured in three areas of Interior Alaska (USA). Four hundred twenty-five sera were tested for evidence of exposure to canine coronavirus by means of an indirect fluorescent antibody procedure. Serum antibody prevalence averaged 70% (167/240) during the spring collection period and 25% (46/185) during the autumn collection ...
R L, Zarnke, J, Evermann, J M, Ver Hoef, M E, McNay, R D, Boertje, C L, Gardner, L G, Adams, B W, Dale, J, Burch   +8 more
openaire   +2 more sources

Evaluating the Antiviral Efficacy of Encapsulated PKC Inhibitor BIM‐I against influenza A Virus Infection

Advanced Healthcare Materials, Volume 15, Issue 8, 23 February 2026.
This study explores nanoparticle delivery of the protein kinase C inhibitor bisindolylmaleimide‐I (BIM‐I) to combat influenza A virus infections. Encapsulation in biodegradable PLGA nanoparticles improved safety while maintaining the compound's strong antiviral activity.
Laura Klement, Jana Ismail, Josefine Schroeder, Amod Godbole, Johanna Schreiber, Christine Weber, Zoltan Cseresnyes, Marc T. Figge, Bettina Löffler, Ulrich S. Schubert, Stephanie Schubert, Christina Ehrhardt, Carsten Hoffmann   +12 more
wiley   +1 more source

Rabbit models of heart disease. [PDF]

, 2008
Human heart disease is a major cause of death and disability. A variety of animal models of cardiac disease have been developed to better understand the etiology, cellular and molecular mechanisms of cardiac dysfunction and novel therapeutic strategies ...
Bers, Donald M, Pogwizd, Steven M
core  

Free ureteral replacement in rats: regeneration of ureteral wall components in the acellular matrix graft. [PDF]

, 1997
ObjectivesTo evaluate ureteral replacement by a free homologous graft of acellular matrix in a rat model.MethodsIn 30 male Sprague-Dawley rats, a 0.3 to 0.8-cm midsegment of the left ureter was resected and replaced with an acellular matrix graft of ...
Dahiya, R, Dahms, SE, Lue, TF, Nunes, L, Piechota, HJ, Tanagho, EA   +5 more
core   +1 more source

Structure‐Based Development of Ultra‐Broad‐Spectrum 3C‐Like Protease Inhibitors

Advanced Science, Volume 13, Issue 11, 23 February 2026.
This study provides an in‐depth analysis of the substrate binding pocket of 3CLpros across all coronavirus species using bioinformatics and structural insights, revealing the critical impact of S2/S4 subsite diversity on the broad‐spectrum activity of approved therapeutics.
Haixia Su, Tianqing Nie, Guofeng Chen, Muya Xiong, Yumin Zhang, Guoqing Wu, Mengyuan You, Hang Xie, Jian He, Yanchao Xiong, Hangchen Hu, Wenfeng Zhao, Minjun Li, Gengfu Xiao, Leike Zhang, Yechun Xu   +15 more
wiley   +1 more source

Prevalence of Korean cats with natural feline coronavirus infections [PDF]

, 2011
Background Feline coronavirus is comprised of two pathogenic biotypes consisting of feline infectious peritonitis virus (FIPV) and feline enteric coronavirus (FECV), which are both divided into two serotypes.
Dong-Jun An, Hye-Young Jeoung, WooSeog Jeong, Jee-Yong Park, Myoung-Heon Lee, Bong-Kyun Park   +5 more
core   +1 more source

Fertility and Early Embryonic Development Toxicity of hzVSF‐v13 in Sprague–Dawley Rats

Journal of Applied Toxicology, Volume 46, Issue 2, Page 560-568, February 2026.
ABSTRACT Humanized virus suppressing factor–variant 13 (hzVSF‐v13), a monoclonal IgG4 antibody, is a potential therapeutic candidate for COVID‐19. Although fertility and embryonic developmental toxicity studies are crucial for the safety evaluation of new drugs, the toxicological profile of hzVSF‐v13 remains unexplored.
Ji‐Seong Jeong, Sang‐Yun Kim, Jinsoo Lee, Seung‐Jin Lee, Onju Ham, Woojin Kim, Wan‐Jung Im, Sungman Park, Kyong‐Cheol Ko, Jong‐Choon Kim, Yong‐Bum Kim   +10 more
wiley   +1 more source

A review of coronavirus infection in the central nervous system of cats and mice. [PDF]

, 2001
Feline infectious peritonitis (FIP) is a common cause of death in cats. Management of this disease has been hampered by difficulties identifying the infection and determining the immunological status of affected cats and by high variability in the ...
Foley, JE, Leutenegger, C
core