Results 1 to 10 of about 11,460 (141)
Tools and techniques for classifying behaviours in canine epilepsy [PDF]
Frontiers in Veterinary Science, 2023 Idiopathic epilepsy is the most common neurological disease in dogs. Similar to humans, dogs with epilepsy often experience behavioural comorbidities such as increased fear, anxiety, and aggression, as reported by their caregivers. Investigations of behaviour in canine epilepsy have yet to untangle interictal and pre and postictal behaviours, prodromal
Lee Niel, Luis Gaitero
exaly +5 more sources
Assessment into the usage of levetiracetam in a canine epilepsy clinic. [PDF]
BMC Vet Res, 2015 Retrospective studies can complement information derived from double-blinded randomized trials. There are multiple retrospective studies reporting good efficacy and tolerability of the anti-epileptic drug levetiracetam (LEV) in human patients with epilepsy; however, reports of LEV's tolerability and efficacy in dogs with epilepsy remain limited.
Packer RM, Nye G, Porter SE, Volk HA.
europepmc +7 more sources
Owner perception of focal seizures in canine epilepsy [PDF]
Veterinary Record, 2017 VETS rely upon owner (carer) reports of seizures to initially diagnose epilepsy in their patients and ongoing seizure diaries to assess changes in seizure frequency (and thus treatment outcomes). In addition, clinical trials of antiepileptic therapies often heavily rely upon owner-reported seizure diaries to assess treatment efficacy. As such, accurate
Rowena M A packer, Holger A Volk
exaly +7 more sources
Urinary Neurotransmitter Patterns Are Altered in Canine Epilepsy. [PDF]
Front Vet Sci, 2022 Epilepsy is the most common chronic neurological disease in humans and dogs. Epilepsy is thought to be caused by an imbalance of excitatory and inhibitory neurotransmission. Intact neurotransmitters are transported from the central nervous system to the periphery, from where they are subsequently excreted through the urine.
Schmidt T +8 more
europepmc +4 more sources
Impact of canine epilepsy on judgement and attention biases. [PDF]
Sci Rep, 2020 AbstractIdiopathic epilepsy (IE) is the most common chronic neurological condition in dogs, characterised by recurrent seizure activity and associated with negative behavioural and cognitive changes. We hypothesised that IE would negatively impact putative affective state, with dogs with IE exhibiting a more pessimistic judgement bias and more negative
Hobbs SL +5 more
europepmc +4 more sources
Treatment in canine epilepsy--a systematic review. [PDF]
BMC Vet Res, 2014 Various antiepileptic drugs (AEDs) are used for the management of canine idiopathic epilepsy (IE). Information on their clinical efficacy remains limited. A systematic review was designed to evaluate existing evidence for the effectiveness of AEDs for presumptive canine IE.
Charalambous M +3 more
europepmc +4 more sources
Pathophysiology of drug-resistant canine epilepsy
Veterinary Journal, 2023 Drug resistance continues to be a major clinical problem in the therapeutic management of canine epilepsies with substantial implications for quality of life and survival times. Experimental and clinical data from human medicine provided evidence for relevant contributions of intrinsic severity of the disease as well as alterations in pharmacokinetics ...
Heidrun Potschka +2 more
exaly +3 more sources
Seizure Forecasting and the Preictal State in Canine Epilepsy. [PDF]
Int J Neural Syst, 2017 The ability to predict seizures may enable patients with epilepsy to better manage their medications and activities, potentially reducing side effects and improving quality of life. Forecasting epileptic seizures remains a challenging problem, but machine learning methods using intracranial electroencephalographic (iEEG) measures have shown promise. A
Varatharajah Y +4 more
europepmc +4 more sources
Preliminary assessment of cognitive impairments in canine idiopathic epilepsy [PDF]
Veterinary Record, 2018 In humans, epilepsy can induce or accelerate cognitive impairment (CI). There is emerging evidence of CI in dogs with idiopathic epilepsy (IE) from recent epidemiological studies.
Rowena M A packer, Holger A Volk
exaly +4 more sources
Placebo Effect in Canine Epilepsy Trials
Journal of Veterinary Internal Medicine, 2010 Abstract Background The placebo effect is a well-recognized phenomenon in human medicine; in contrast, little information exists on the effect of placebo administration in veterinary patients.
Karen R Munana
exaly +3 more sources