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H3N2 canine influenza virus NS1 protein inhibits canine NLRP3 inflammasome activation

Veterinary Immunology and Immunopathology, 2022
Inflammation is an innate immune response of the body against pathogens and other irritants. The NLRP3 (NACHT, LRR and PYD domains-containing protein 3) inflammasome is a major player in the inflammatory response against pathogenic microorganisms. In this study, we analyzed the relationship between the NLRP3 inflammasome and the influenza virus NS1 ...
Pan, Tao   +6 more
openaire   +2 more sources

Canine influenza virus

Veterinary Record, 2005
SIR, – I feel we should be on the look out for any suspect cases of canine influenza, following outbreaks in the USA ( VR , October 15, 2005, vol 157, p 459). Have the universities and laboratories in the UK prepared for the likely introduction of this disease from ‘across the pond ...
K C, Smith   +3 more
openaire   +4 more sources

Evidence of H3N2 canine influenza virus infection before 2007

Veterinary Record, 2012
Emergence of severe respiratory disease in pet dogs caused by avian-origin influenza A virus, subtype H3N2 (canine influenza virus, CIV), has been reported in Korea since 2007. To ascertain the date of introduction of H3N2 CIV in dog populations in Korea, a serological retrospective study was carried out using archived sera.
Y-N, Lee   +10 more
openaire   +2 more sources

Transmission of canine influenza virus (H3N8) among susceptible dogs

Veterinary Microbiology, 2010
Canine influenza virus (CIV) is an emerging pathogen that causes acute respiratory disease in dogs. As with any communicable disease, dog-to-dog transmission of CIV occurs when infected dogs come in contact with other susceptible dogs. We demonstrate that CIV transmission occurs readily from CIV-infected dogs to susceptible dogs following co-mingling ...
Faris F, Jirjis   +5 more
openaire   +2 more sources

Genetic characterization of canine influenza A virus (H3N2) in Thailand

Virus Genes, 2013
In January 2012, several clinical cases of dogs with flu-like symptoms, including coughing, sneezing, nasal discharge, and fever, were reported in a small-animal hospital located in Bangkok, Thailand. One influenza A virus was identified and characterized as an avian-like influenza virus H3N2. The virus was named A/canine/Thailand/CU-DC5299/12.
Napawan, Bunpapong   +10 more
openaire   +2 more sources

Canine influenza virus: cross‐species transmission from horses

Veterinary Record, 2007
SIR, — In a letter to The Veterinary Record in 2005 (November 5, 2005, vol 157, p 599), Dr Ken Smith and colleagues from the Animal Health Trust (aht) made reference to the retrospective confirmation of a limited but fatal outbreak of respiratory disease attributable to h3n8 equine influenza ...
Richard Newton   +10 more
openaire   +1 more source

Pathology in dogs with experimental canine H3N2 influenza virus infection

Research in Veterinary Science, 2010
Avian-lineage H3N2 canine influenza virus (CIV)-associated respiratory disease, which can be fatal, emerged in South Korean dogs in 2007. We show here that dogs experimentally infected with CIV only developed respiratory tract diseases, as no extrapulmonary lesions and virus antigens were detected.
K, Jung   +5 more
openaire   +2 more sources

Cellular microRNAs influence replication of H3N2 canine influenza virus in infected cells

Veterinary Microbiology, 2021
MicroRNAs (miRNAs) are known to play important regulatory roles in host-virus interactions. Avian-origin H3N2 canine influenza virus (CIV) has emerged as the most prevalent subtype among dogs in Asia since 2007. To evaluate the roles of host miRNAs in H3N2 CIV infection, here, miRNA profiles obtained from primary canine bronchiolar epithelial cells ...
Xing Xie   +8 more
openaire   +2 more sources

Prevalence of canine influenza virus A (H3N8) in dogs in Germany

The Veterinary Journal, 2014
The aim of this study was to investigate the prevalence of CIV H3N8 in dogs in Germany. Blood samples from 272 clinically healthy dogs and 35 dogs with acute respiratory signs were screened for antibodies against influenza virus by ELISA and haemagglutination inhibition (HI) assay; positive samples were further tested by fluorescent antibody test (FAT)
Bianka, Schulz   +5 more
openaire   +2 more sources

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