Results 1 to 10 of about 52,761 (267)

Potential mechanisms mediating PM2.5-induced alterations of H3N2 influenza virus infection and cytokine production in human bronchial epithelial cells

Ecotoxicology and Environmental Safety, 2023
Exposure to particulate matter (PM) has been associated with increased hospital admissions for influenza. Airway epithelial cells are a primary target for inhaled environmental insults including fine PM (PM2.5) and influenza viruses.
Yinbiao Wang, Rui Zhang, Fuyun Yang, Lin Yang, Qingmei Li, Junqing Guo, Xiao Liu, Jie Song, Guofu Zhang, Juan Li, Zhen An, Neil E. Alexis, Ilona Jaspers, Weidong Wu   +13 more
doaj   +3 more sources

H3N2 Influenza Viruses in Humans: Viral Mechanisms, Evolution, and Evaluation

Human Vaccines and Immunotherapeutics, 2018
Annual seasonal influenza vaccines are composed of two influenza A strains representing the H1N1 and H3N2 subtypes, and two influenza B strains representing the Victoria and Yamagata lineages.
Ted Ross
exaly   +3 more sources

Development of the H3N2 influenza microneedle vaccine for cross-protection against antigenic variants

Scientific Reports, 2022
Due to the continuously mutating nature of the H3N2 virus, two aspects were considered when preparing the H3N2 microneedle vaccines: (1) rapid preparation and (2) cross-protection against multiple antigenic variants.
Yura Shin, Jeonghun Kim, Jong Hyeon Seok, Heedo Park, Hye-Ran Cha, Si Hwan Ko, Jae Myun Lee, Man-Seong Park, Jung-Hwan Park   +8 more
doaj   +2 more sources

An epitope-optimized human H3N2 influenza vaccine induces broadly protective immunity in mice and ferrets

npj Vaccines, 2022
There is a crucial need for an improved H3N2 influenza virus vaccine due to low vaccine efficacy rates and increased morbidity and mortality associated with H3N2-dominated influenza seasons.
Brianna L. Bullard, Jennifer DeBeauchamp, Matthew J. Pekarek, Erika Petro-Turnquist, Peter Vogel, Richard J. Webby, Eric A. Weaver   +6 more
doaj   +2 more sources

Evolution of Human H3N2 Influenza Virus Receptor Specificity Has Substantially Expanded the Receptor-Binding Domain Site

Cell Host and Microbe
Summary: Hemagglutinins (HAs) from human influenza viruses descend from avian progenitors that bind α2–3-linked sialosides, and must adapt to glycans with α2–6-linked sialic acids on human airway cells to transmit within the human population. Since their
Andrew James Thompson, James C. Paulson, Corwin Nycholat   +2 more
exaly   +2 more sources

Isolation and Genetic Characterization of Emerging H3N2 Canine Influenza Virus in Guangdong Province, Southern China, 2018–2021

Frontiers in Veterinary Science, 2022
H3N2 canine influenza virus (CIV) emerged in dogs in China or Korea around 2005 and was first reported in 2008. In 2015, H3N2 CIV was detected in the United States and caused a huge outbreak.
Gang Lu, Shoujun Li, Jiajun Ou
exaly   +3 more sources

H3N2 Avian Influenza Viruses Detected in Live Poultry Markets in China Bind to Human-Type Receptors and Transmit in Guinea Pigs and Ferrets

Emerging Microbes and Infections, 2019
The H3N2 influenza viruses became widespread in humans during the 1968 H3N2 pandemic and have been a major cause of influenza epidemics ever since. Different lineages of H3N2 influenza viruses are also commonly found in animals. If a different lineage of
Chengjun Li, Hualan Chen, XiJun He
exaly   +3 more sources

Study of the driving factors of the abnormal influenza A (H3N2) epidemic in 2022 and early predictions in Xiamen, China

BMC Infectious Diseases
Background Influenza outbreaks have occurred frequently these years, especially in the summer of 2022 when the number of influenza cases in southern provinces of China increased abnormally.
Hansong Zhu, Feifei Qi, Xiaoying Wang, Yanhua Zhang, Fangjingwei Chen, Zhikun Cai, Yuyan Chen, Kaizhi Chen, Hongbin Chen, Zhonghang Xie, Guangmin Chen, Xiaoyuan Zhang, Xu Han, Shenggen Wu, Si Chen, Yuying Fu, Fei He, Yuwei Weng, Jianming Ou   +18 more
doaj   +2 more sources

Characterization and Evolutionary Analysis of a Novel H3N2 Influenza A Virus Glycosylation Motif in Southern China

Frontiers in Microbiology, 2020
An influenza A (H3N2) virus epidemic occurred in China in 2017 and the causative strain failed to bind red blood cells (RBCs), which may affect receptor binding and antibody recognition.
Lee-Fong Yau, Wenjun Song, Zi-Feng Yang
exaly   +3 more sources

The frequency and outcome of Influenza in children admitted to Tabriz children's training and treatment center in Northwest Iran During 2014-2019 [PDF]

مجله پزشکی دانشگاه علوم پزشکی تبریز, 2023
Background. Influenza causes various seasonal respiratory diseases, resulting in significant morbidity and mortality in children. Influenza is a highly contagious disease causing global pandemics. This study aimed to investigate the frequency and outcome
Babak Abdinia, Azar Dastranji, Ali Akbar Abedini, Iman Moghbel, Golnaz Mobayen   +4 more
doaj   +1 more source