Results 41 to 50 of about 52,761 (267)

Fifty Years of Influenza A(H3N2) Following the Pandemic of 1968.

American Journal of Public Health, 2020
In 2018, the world commemorated the centennial of the 1918 influenza A(H1N1) pandemic, the deadliest pandemic in recorded history; however, little mention was made of the 50th anniversary of the 1968 A(H3N2) pandemic.
Barbara J Jester, T. Uyeki, D. Jernigan
semanticscholar   +1 more source

Timescales of influenza A/H3N2 antibody dynamics

PLOS Biology, 2017
Abstract Human immunity influences the evolution and impact of novel influenza strains. Because individuals are infected with multiple influenza strains during their lifetime and each virus can generate a cross-reactive antibody response, it is challenging to quantify the processes that shape observed immune responses, or to reliably ...
Adam J. Kucharski, Justin Lessler, Derek A. T. Cummings, Steven Riley   +3 more
openaire   +5 more sources

Fatal Myopericarditis Following an Influenza A (H3N2) Infection [PDF]

American Journal of Case Reports, 2018
BACKGROUND Influenza viruses induce uncomplicated infections in most cases in individuals with no known predisposing factors. Acute febrile illness is generally limited to upper respiratory symptoms and several constitutional symptoms, including headache, lethargy, and myalgia.
Lefeuvre, Caroline, Behillil, Sylvie, Triau, Stéphane, Monteiro-Rodrigues, Antonio, Templier, François, Tri Tran, Cong, Le Guillou-Guillemette, Hélène, Lunel-Fabiani, Françoise, Enouf, Vincent, Ducancelle, Alexandra   +9 more
openaire   +3 more sources

An Outbreak of Influenza A (H3N2) in a Nursing Home

Journal of the Japanese Association for Infectious Diseases, 1996
In the nursing home belonging to our hospital, an outbreak of influenza A (H3N2) occurred in January 1995, and we studied 23 elderly residents with influenza A infection. Twenty three residents with influenza A (8 males and 15 females) ranged in age from 67 to 95 years (average 83.1 years), 91.3% of them were bedridden.
YAMAKOSHI, Masahiro, SUZUKI, Kanzou, YAMAMOTO, Toshinobu, YAMAMOTO, Toshiyuki, GOTO, Noriko, NAKAKITA, Takashi, YAMANAKA, Katsumi   +6 more
openaire   +3 more sources

Chemoenzymatic Synthesis of 6‐Sulfo Sialyl Lewisx Containing Glycans to Probe the Receptor Specificity of MERS Coronavirus

Angewandte Chemie, EarlyView.
A chemoenzymatic methodology is described that provided a panel of 6‐sulfo sialyl Lewisx‐containing glycans that were probed for receptor specificity of MERS‐CoV. Although the fucoside of 6‐sulfo‐SLex does not directly interact with the spike, it pre‐organizes the molecule into a conformation to allow a salt bridge between the sulfate and the ...
Yunfei Wu, Anne L.M. Kimpel, Jacobus P. van Trijp, Elif Uslu, Gaёl M. Vos, Luca Unione, Robert P. de Vries, Geert‐Jan Boons   +7 more
wiley   +2 more sources

Genetic and Antigenic Characterization of an Influenza A(H3N2) Outbreak in Cambodia and the Greater Mekong Subregion during the COVID-19 Pandemic, 2020

Journal of Virology, 2021
The 2019 coronavirus disease (COVID-19) pandemic has significantly altered the circulation patterns of respiratory diseases worldwide and disrupted continued surveillance in many countries.
J. Siegers, V. Dhanasekaran, Ruo-Peng Xie, Yi-Mo Deng, Sarika Patel, Vanra Ieng, J. Moselen, Heidi Peck, Ammar Aziz, Borann Sarr, S. Chin, S. Heng, A. Khalakdina, M. Kinzer, D. Chau, P. Raftery, V. Duong, L. Sovann, I. Barr, E. Karlsson   +19 more
semanticscholar   +1 more source

Early Prediction of Antigenic Transitions for Influenza A H3N2

PLOS Computational Biology, 2019
Abstract Influenza A/H3N2 is a rapidly evolving virus which experiences major antigenic transitions every two to eight years. Anticipating the timing and outcome of transitions is critical to developing effective seasonal influenza vaccines.
Lauren A. Castro, Trevor Bedford, Lauren Ancel Meyers   +2 more
openaire   +5 more sources

Comparative analysis of Hemagglutinin of 2013 H3N2 Influenza A virus Indicates its Evolution from 1968 H3N2 Pandemic Influenza A virus

, 2020
Emergence of influenza A H3N2 is alarming. Strain 2013 H3N2 has H1 subtype Haemagglutinin (HA) gene segment replaced with a H3 HA gene segment. The vulnerability of the humans to H3 may be directly proportional to the HA alterations.
Sneham Tiwari, Amit K Banerjee, Debadatta Nayak, Neelima Arora, Shailendra K Saxena, Srinivasulu Gadugu, Swatantra Kumar, Sai V Chitti, Raj K Manchanda, Vimal K Maurya, Anil Khurana   +10 more
core   +1 more source

Highly Cross-Reactive and Protective Influenza A Virus H3N2 Hemagglutinin- and Neuraminidase-Specific Human Monoclonal Antibodies

Microbiology Spectrum, 2023
Due to antigenic drift and shift of influenza A viruses (IAV) and the tendency to elicit predominantly strain-specific antibodies, humanity remains susceptible to new strains of seasonal IAV and is at risk from viruses with pandemic potential for which ...
Michael Piepenbrink, Fatai Oladunni, Aitor Nogales, Ahmed M. Khalil, Theresa Fitzgerald, Madhubanti Basu, Christopher Fucile, David J. Topham, Alexander F. Rosenberg, Luis Martinez-Sobrido, James J. Kobie   +10 more
doaj   +1 more source

H3N2 hexamaps for HAI titers.

, 2022
a) Hexamaps visualizing H3N2 HAI mean log titers as a function of age, calendar year, and birth year in the data. b) Corresponding hexamaps for the mean log titers predicted by the H3N2 subtype-specific model.
Sergio Ojeda (2847896), Roger Lopez (12119848), Amy J. Schiller (12119845), Mayuri Patel (308695), Richard J. Webby (6849578), Martha I. Nelson (7538087), Aubree Gordon (109169), Andrew F. Brouwer (12119842), Angel Balmaseda (109173), Lionel Gresh (404053), Guillermina Kuan (179743)   +10 more
core   +1 more source