Results 41 to 50 of about 51,349 (223)

An Outbreak of Influenza A (H3N2) in a Nursing Home

open access: yesJournal of the Japanese Association for Infectious Diseases, 1996
In the nursing home belonging to our hospital, an outbreak of influenza A (H3N2) occurred in January 1995, and we studied 23 elderly residents with influenza A infection. Twenty three residents with influenza A (8 males and 15 females) ranged in age from 67 to 95 years (average 83.1 years), 91.3% of them were bedridden.
M, Yamakoshi   +6 more
openaire   +3 more sources

Influenza Evolution and H3N2 Vaccine Effectiveness, with Application to the 2014/2015 Season [PDF]

open access: yes, 2016
Influenza A is a serious disease that causes significant morbidity and mortality, and vaccines against the seasonal influenza disease are of variable effectiveness.
Deem, Michael W., Li, Xi
core   +2 more sources

Heterologous prime-boost vaccination with H3N2 influenza viruses of swine favors cross-clade antibody responses and protection [PDF]

open access: yes, 2017
The emergence of multiple novel lineages of H1 and H3 influenza A viruses in swine has confounded control by inactivated vaccines. Because of substantial genetic and geographic heterogeneity among circulating swine influenza viruses, one vaccine strain ...
Claes, Gerwin   +8 more
core   +2 more sources

Early Prediction of Antigenic Transitions for Influenza A H3N2

open access: yesPLOS Computational Biology, 2019
Abstract Influenza A/H3N2 is a rapidly evolving virus which experiences major antigenic transitions every two to eight years. Anticipating the timing and outcome of transitions is critical to developing effective seasonal influenza vaccines.
Lauren Castro   +2 more
openaire   +4 more sources

An epitope-optimized human H3N2 influenza vaccine induces broadly protective immunity in mice and ferrets

open access: yesnpj Vaccines, 2022
There is a crucial need for an improved H3N2 influenza virus vaccine due to low vaccine efficacy rates and increased morbidity and mortality associated with H3N2-dominated influenza seasons.
Brianna L. Bullard   +6 more
doaj   +1 more source

International Laboratory Comparison of Influenza Microneutralization Assays for A(H1N1) pdm09, A(H3N2), and A(H5N1) Influenza Viruses by CONSISE [PDF]

open access: yes, 2015
The microneutralization assay is commonly used to detect antibodies to influenza virus, and multiple protocols are used worldwide. These protocols differ in the incubation time of the assay as well as in the order of specific steps, and even within ...
Engelhardt, OG   +9 more
core   +1 more source

H3N2 Canine Influenza Virus Infection in a Dog [PDF]

open access: yesVeterinary Pathology, 2016
In 2015, H3N2 canine influenza emerged in dogs in the greater Chicago area. During this time, a 10-year-old German Shepherd dog presented to the referring veterinarian with lethargy and coughing that quickly progressed to death. This report describes the macroscopic and microscopic lesions and the molecular testing performed to identify the novel ...
C E, Watson, C, Bell, K, Toohey-Kurth
openaire   +2 more sources

Highly Cross-Reactive and Protective Influenza A Virus H3N2 Hemagglutinin- and Neuraminidase-Specific Human Monoclonal Antibodies

open access: yesMicrobiology Spectrum, 2023
Due to antigenic drift and shift of influenza A viruses (IAV) and the tendency to elicit predominantly strain-specific antibodies, humanity remains susceptible to new strains of seasonal IAV and is at risk from viruses with pandemic potential for which ...
Michael Piepenbrink   +10 more
doaj   +1 more source

Selective engagement of FcγRIV by a M2e-specific single domain antibody construct protects against influenza A virus infection [PDF]

open access: yes, 2019
Lower respiratory tract infections, such as infections caused by influenza A viruses, are a constant threat for public health. Antivirals are indispensable to control disease caused by epidemic as well as pandemic influenza A.
Ballegeer, Marlies   +10 more
core   +2 more sources

Seasonal influenza vaccination expands hemagglutinin-specific antibody breadth to older and future A/H3N2 viruses

open access: yesnpj Vaccines, 2022
History of influenza A/H3N2 exposure, especially childhood infection, shape antibody responses after influenza vaccination and infection, but have not been extensively studied.
Nina Urke Ertesvåg   +5 more
doaj   +1 more source

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