Results 1 to 10 of about 1,954,549 (170)
Biomedicine Hub, 2021 We report the disparate clinical progression of a couple infected by SARS-CoV-2 based on their immune checkpoint (IC) levels and immune cell distribution in blood from admission to exitus in patient 1 and from admission to discharge and recovery in ...
Alejandro Martín-Quirós +13 more
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CD83 expression characterizes precursor exhausted T cell population
Communications Biology, 2023 CD83, a member of the immunoglobulin superfamily, is a novel marker to discriminate precursor exhausted T cells from terminally exhausted and bystander tumor-infiltrating T-lymphocytes.
Zhiwen Wu +10 more
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Identification of sSIGLEC5 and sLAG3 as New Relapse Predictors in Lung Cancer
Biomedicines, 2022 Lung cancer (LC) continues to be the leading cause of cancer-related deaths in both men and women worldwide. After complete tumour resection, around half of the patients suffer from disease relapse, emphasising the critical need for robust relapse ...
Karla Montalbán-Hernández +8 more
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Bothrops Jararaca Snake Venom Modulates Key Cancer-Related Proteins in Breast Tumor Cell Lines
Toxins, 2021 Cancer is characterized by the development of abnormal cells that divide in an uncontrolled way and may spread into other tissues where they may infiltrate and destroy normal body tissue.
Carolina Yukiko Kisaki +9 more
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Sequential Immune Responses: The Weapons of Immunity [PDF]
Journal of Innate Immunity, 2015 Sequential immune responses (SIR) is a new model that describes what ‘immunity' means in higher animals. Existing models, such as self/nonself discrimination or danger, focus on how immune responses are initiated. However, initiation is not protection. SIR describes the actual immune responses that provide protection.
Mills, C. D. +3 more
openaire +3 more sources
PD-L1/PD-1 crosstalk in colorectal cancer: are we targeting the right cells?
BMC Cancer, 2018 Background The analysis of tumour-infiltrating immune cells within patients’ tumour samples in colorectal cancer (CRC) has become an independent predictor of patient survival.
Ramón Cantero-Cid +13 more
doaj +1 more source
Scientific Reports, 2020 Envenoming by viperid snakes results in a complex pattern of tissue damage, including hemorrhage, which in severe cases may lead to permanent sequelae. Snake venom metalloproteinases (SVMPs) are main players in this pathogenesis, acting synergistically ...
Amanda F. Asega +7 more
doaj +1 more source
Scientific Reports, 2021 The Coronavirus Disease of 2019 (COVID-19) pandemic caused by SARS-CoV-2 led the Spanish government to impose a national lockdown in an attempt to control the spread of the infection.
Patricia Torres Martínez +10 more
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The perioperative immune response [PDF]
Current Opinion in Critical Care, 2015 A host of immune modulators are now available in clinical practice. The perioperative period is characterized by profound alterations in host immunity, which can result in poor outcomes, which include infection, cancer recurrence and organ failure. Manipulation of the perioperative immune response has the potential to improve outcomes.
O'Dwyer, MJ, Owen, HC, Torrance, HDT
openaire +3 more sources
Toxins, 2021 Hemorrhage induced by snake venom metalloproteinases (SVMPs) is a complex phenomenon that involves capillary disruption and blood extravasation. HF3 (hemorrhagic factor 3) is an extremely hemorrhagic SVMP of Bothrops jararaca venom.
Luciana Bertholim +7 more
doaj +1 more source