Results 1 to 10 of about 3,299,262 (309)
Biomedicine Hub, 2021 We report the disparate clinical progression of a couple infected by SARS-CoV-2 based on their immune checkpoint (IC) levels and immune cell distribution in blood from admission to exitus in patient 1 and from admission to discharge and recovery in ...
Alejandro Martín-Quirós +13 more
doaj +1 more source
CD83 expression characterizes precursor exhausted T cell population
Communications Biology, 2023 CD83, a member of the immunoglobulin superfamily, is a novel marker to discriminate precursor exhausted T cells from terminally exhausted and bystander tumor-infiltrating T-lymphocytes.
Zhiwen Wu +10 more
doaj +1 more source
Identification of sSIGLEC5 and sLAG3 as New Relapse Predictors in Lung Cancer
Biomedicines, 2022 Lung cancer (LC) continues to be the leading cause of cancer-related deaths in both men and women worldwide. After complete tumour resection, around half of the patients suffer from disease relapse, emphasising the critical need for robust relapse ...
Karla Montalbán-Hernández +8 more
doaj +1 more source
Transcriptome-wide analysis reveals different categories of response to a standardised immune challenge in a wild rodent [PDF]
, 2020 Individuals vary in their immune response and, as a result, some are more susceptible to infectious disease than others. Little is known about the nature of this individual variation in natural populations, or which components of immune pathways are most
Arriero, E +7 more
core +4 more sources
Bothrops Jararaca Snake Venom Modulates Key Cancer-Related Proteins in Breast Tumor Cell Lines
Toxins, 2021 Cancer is characterized by the development of abnormal cells that divide in an uncontrolled way and may spread into other tissues where they may infiltrate and destroy normal body tissue.
Carolina Yukiko Kisaki +9 more
doaj +1 more source
Innate immune response restarts adaptive immune response in tumors
Frontiers in Immunology, 2023 The imbalance of immune response plays a crucial role in the development of diseases, including glioblastoma. It is essential to comprehend how the innate immune system detects tumors and pathogens. Endosomal and cytoplasmic sensors can identify diverse cancer cell antigens, triggering the production of type I interferon and pro-inflammatory cytokines.
Wen-shan Li +11 more
openaire +3 more sources
PD-L1/PD-1 crosstalk in colorectal cancer: are we targeting the right cells?
BMC Cancer, 2018 Background The analysis of tumour-infiltrating immune cells within patients’ tumour samples in colorectal cancer (CRC) has become an independent predictor of patient survival.
Ramón Cantero-Cid +13 more
doaj +1 more source
Scientific Reports, 2020 Envenoming by viperid snakes results in a complex pattern of tissue damage, including hemorrhage, which in severe cases may lead to permanent sequelae. Snake venom metalloproteinases (SVMPs) are main players in this pathogenesis, acting synergistically ...
Amanda F. Asega +7 more
doaj +1 more source
Regulatory immune cells in transplantation [PDF]
, 2012 Immune regulation is fundamental to any immune response to ensure that it is appropriate for the perceived threat to the host. Following cell and organ transplantation, it is essential to control the innate immune response triggered by the injured ...
Bushell, Andrew +2 more
core +1 more source
The immune response to malaria in utero. [PDF]
, 2020 Malaria causes tremendous early childhood morbidity and mortality, providing an urgent impetus for the development of a vaccine that is effective in neonates.
Feeney, Margaret E
core +1 more source