Results 11 to 20 of about 8,136,838 (310)
Biomedicine Hub, 2021 We report the disparate clinical progression of a couple infected by SARS-CoV-2 based on their immune checkpoint (IC) levels and immune cell distribution in blood from admission to exitus in patient 1 and from admission to discharge and recovery in ...
Alejandro Martín-Quirós +13 more
doaj +1 more source
CD83 expression characterizes precursor exhausted T cell population
Communications Biology, 2023 CD83, a member of the immunoglobulin superfamily, is a novel marker to discriminate precursor exhausted T cells from terminally exhausted and bystander tumor-infiltrating T-lymphocytes.
Zhiwen Wu +10 more
doaj +1 more source
Identification of sSIGLEC5 and sLAG3 as New Relapse Predictors in Lung Cancer
Biomedicines, 2022 Lung cancer (LC) continues to be the leading cause of cancer-related deaths in both men and women worldwide. After complete tumour resection, around half of the patients suffer from disease relapse, emphasising the critical need for robust relapse ...
Karla Montalbán-Hernández +8 more
doaj +1 more source
Bothrops Jararaca Snake Venom Modulates Key Cancer-Related Proteins in Breast Tumor Cell Lines
Toxins, 2021 Cancer is characterized by the development of abnormal cells that divide in an uncontrolled way and may spread into other tissues where they may infiltrate and destroy normal body tissue.
Carolina Yukiko Kisaki +9 more
doaj +1 more source
Sequential Immune Responses: The Weapons of Immunity [PDF]
Journal of Innate Immunity, 2015 Sequential immune responses (SIR) is a new model that describes what ‘immunity' means in higher animals. Existing models, such as self/nonself discrimination or danger, focus on how immune responses are initiated. However, initiation is not protection. SIR describes the actual immune responses that provide protection.
Mills, C. D. +3 more
openaire +3 more sources
PD-L1/PD-1 crosstalk in colorectal cancer: are we targeting the right cells?
BMC Cancer, 2018 Background The analysis of tumour-infiltrating immune cells within patients’ tumour samples in colorectal cancer (CRC) has become an independent predictor of patient survival.
Ramón Cantero-Cid +13 more
doaj +1 more source
Scientific Reports, 2020 Envenoming by viperid snakes results in a complex pattern of tissue damage, including hemorrhage, which in severe cases may lead to permanent sequelae. Snake venom metalloproteinases (SVMPs) are main players in this pathogenesis, acting synergistically ...
Amanda F. Asega +7 more
doaj +1 more source
Extracorporeal Circulation-Related Immune Response
, 2023 Forms of extracorporeal circulation are increasingly used to support critically ill patients. Extracorporeal membrane oxygenation (ECMO) and renal replacement therapy (RRT) are two of the most widely used and are employed as bridges to recovery or as ...
Heinsar, S +7 more
core +1 more source
A strong immune response in young adult honeybees masks their increased susceptibility to infection compared to older bees [PDF]
, 2012 Honeybees, Apis mellifera, show age-related division of labor in which young adults perform maintenance ("housekeeping") tasks inside the colony before switching to outside foraging at approximately 23 days old. Disease resistance is an important feature
James C Bull +53 more
core +1 more source
Physiology and Pathology of Innate Immune Response Against Pathogens [PDF]
, 2017 Pathogen infections are recognized by the immune system, which consists of two types of responses: an innate immune response and an antigen-specific adaptive immune response.
Contreras Cordero, Juan Francisco +9 more
core +1 more source