Results 11 to 20 of about 1,963,524 (269)

The perioperative immune response [PDF]

open access: yesCurrent Opinion in Critical Care, 2015
A host of immune modulators are now available in clinical practice. The perioperative period is characterized by profound alterations in host immunity, which can result in poor outcomes, which include infection, cancer recurrence and organ failure. Manipulation of the perioperative immune response has the potential to improve outcomes.
O'Dwyer, MJ, Owen, HC, Torrance, HDT
openaire   +3 more sources

Changes in Iron Metabolism Induced by Anti-Interleukin-6 Receptor Monoclonal Antibody are Associated with an Increased Risk of Infection

open access: yesPharmaceuticals, 2019
(1) Background: Treatment of patients with rheumatoid arthritis (RA) with an anti-IL-6 receptor (anti-IL-6R) monoclonal antibody (tocilizumab) has been found to influence iron metabolism.
Renata Ribeiro   +3 more
doaj   +1 more source

In-vivo expressed Mycobacterium tuberculosis antigens recognised in three mouse strains after infection and BCG vaccination

open access: yesnpj Vaccines, 2021
Novel tuberculosis (TB)-vaccines preferably should (i) boost host immune responses induced by previous BCG vaccination and (ii) be directed against Mycobacterium tuberculosis (Mtb) proteins expressed throughout the Mtb infection-cycle.
Mariateresa Coppola   +7 more
doaj   +1 more source

Control of immune responses by gene immunization

open access: yesAnnals of Medicine, 1998
The use of plasmid DNA to elicit immune responses has greatly increased our ability to skew the desired immune response to a particular antigen. DNA immunization elicits potent cell-mediated responses including humoral immunity as well as cytolytic T-lymphocyte immunity.
D J, Lee, M, Corr, D A, Carson
openaire   +2 more sources

Immune Response to Neonatal Genetic Immunization

open access: yesVirology, 1997
The effect of genetic immunization of neonatal mice was tested with a plasmid vector expressing the rabies virus glycoprotein. Mice inoculated within 24 hr after birth with the plasmid DNA developed antibodies as well as T helper cells to the rabies virus glycoprotein.
Wang, Yijie   +3 more
openaire   +2 more sources

A Multiomics Approach Unravels New Toxins With Possible In Silico Antimicrobial, Antiviral, and Antitumoral Activities in the Venom of Acanthoscurria rondoniae

open access: yesFrontiers in Pharmacology, 2020
The Araneae order is considered one of the most successful groups among venomous animals in the world. An important factor for this success is the production of venoms, a refined biological fluid rich in proteins, short peptides and cysteine-rich ...
Guilherme A. Câmara   +7 more
doaj   +1 more source

Immune Responses to Retroviruses [PDF]

open access: yesAnnual Review of Immunology, 2018
Retroviruses are genome invaders that have shared a long history of coevolution with vertebrates and their immune system. Found endogenously in genomes as traces of past invasions, retroviruses are also considerable threats to human health when they exist as exogenous viruses such as HIV.
Saez-Cirion, Asier, Manel, Nicolas
openaire   +3 more sources

Obstructive Sleep Apnea Monocytes Exhibit High Levels of Vascular Endothelial Growth Factor Secretion, Augmenting Tumor Progression

open access: yesMediators of Inflammation, 2018
Obstructive sleep apnea (OSA) is a syndrome characterized by repeated pauses in breathing induced by a partial or complete collapse of the upper airways during sleep.
Carolina Cubillos-Zapata   +10 more
doaj   +1 more source

Fibroblast Growth Factor 2 lethally sensitizes cancer cells to stress‐targeted therapeutic inhibitors

open access: yesMolecular Oncology, 2019
In malignant transformation, cellular stress‐response pathways are dynamically mobilized to counterbalance oncogenic activity, keeping cancer cells viable.
Matheus H. Dias   +10 more
doaj   +1 more source

Rondonin: antimicrobial properties and mechanism of action

open access: yesFEBS Open Bio, 2021
Infectious diseases are among the major causes of death in the human population. A wide variety of organisms produce antimicrobial peptides (AMPs) as part of their first line of defense.
Katie C. T. Riciluca   +5 more
doaj   +1 more source

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