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The Coronavirus Disease of 2019 (COVID-19) pandemic caused by SARS-CoV-2 led the Spanish government to impose a national lockdown in an attempt to control the spread of the infection.
Patricia Torres Martínez +10 more
doaj +1 more source
Polyomavirus BK-specific cellular immune response in Kidney transplant recipients [PDF]
Polyomavirus BK is an emerging pathogen in KT recipients. New potent immunosuppressive drugs promote reactivation and replication of BKV and progression towards PVAN.
Binggeli, Simone Young
core +1 more source
ATR Kinase Is a Crucial Player Mediating the DNA Damage Response in Trypanosoma brucei
DNA double-strand breaks (DSBs) are among the most deleterious lesions that threaten genome integrity. To address DSBs, eukaryotic cells of model organisms have evolved a complex network of cellular pathways that are able to detect DNA damage, activate a
Paula Andrea Marin +10 more
doaj +1 more source
Control of immune responses by gene immunization
The use of plasmid DNA to elicit immune responses has greatly increased our ability to skew the desired immune response to a particular antigen. DNA immunization elicits potent cell-mediated responses including humoral immunity as well as cytolytic T-lymphocyte immunity.
D J, Lee, M, Corr, D A, Carson
openaire +2 more sources
The transcriptional response of Drosophila melanogaster to infection with the sigma virus (Rhabdoviridae). [PDF]
Bacterial and fungal infections induce a potent immune response in Drosophila melanogaster, but it is unclear whether viral infections induce an antiviral immune response.
Carpenter Jennifer +33 more
core +2 more sources
(1) Background: Treatment of patients with rheumatoid arthritis (RA) with an anti-IL-6 receptor (anti-IL-6R) monoclonal antibody (tocilizumab) has been found to influence iron metabolism.
Renata Ribeiro +3 more
doaj +1 more source
Hemorrhage induced by snake venom metalloproteinases (SVMPs) is a complex phenomenon that involves capillary disruption and blood extravasation. HF3 (hemorrhagic factor 3) is an extremely hemorrhagic SVMP of Bothrops jararaca venom.
Luciana Bertholim +7 more
doaj +1 more source
Innate immune response to intramammary infection with Serratia marcescens and Streptococcus uberis [PDF]
Streptococcus uberis and Serratia marcescens are Gram-positive and Gram-negative bacteria, respectively, that induce clinical mastitis. Once initial host barrier systems have been breached by these pathogens, the innate immune system provides the next ...
Bannerman, Douglas +20 more
core +1 more source
Leishmania major Infection in Humanized Mice Induces Systemic Infection and Provokes a Nonprotective Human Immune Response [PDF]
Background: Leishmania (L.) species are the causative agent of leishmaniasis. Due to the lack of efficient vaccine candidates, drug therapies are the only option to deal with cutaneous leishmaniasis.
Uwe Ritter (130470) +31 more
core +2 more sources
Anesthetics, immune cells, and immune responses
General anesthesia accompanied by surgical stress is considered to suppress immunity, presumably by directly affecting the immune system or activating the hypothalamic-pituitary-adrenal axis and the sympathetic nervous system. Along with stress such as surgery, blood transfusion, hypothermia, hyperglycemia, and postoperative pain, anesthetics per se ...
Shin, Kurosawa, Masato, Kato
openaire +2 more sources

