Results 51 to 60 of about 2,356 (118)

Predicting Antigenic Variants of Influenza A/H3N2 Viruses

Emerging Infectious Diseases, 2004
Current inactivated influenza vaccines provide protection when vaccine antigens and circulating viruses share a high degree of similarity in hemagglutinin protein. Five antigenic sites in the hemagglutinin protein have been proposed, and 131 amino acid positions have been identified in the five antigenic sites.
Min-Shi Lee, Jack Si-En Chen
openaire   +3 more sources

Detection of Seasonal Influenza H1N1 and H3N2 Viruses using RT-PCR Assay during 2009 Flu Pandemic in Golestan Province

Medical Laboratory Journal, 2014
Background and Objective: The emergence of a novel H1N1influenza A virus of animal origin with transmissibility from human to human poses pandemic concern.
S Zhand, A Tabaraei, A moradi, f Fotoohi, N Javid, M Bazoori, E Haji Mohammadi, A Ghaemi   +7 more
doaj  

Antigenic and genomic relation between human influenza A (H3N2) viruses circulating in Argentina during 1998 and the H3N2 vaccine component [PDF]

Revista Panamericana de Salud Pública, 2001
Due to the lack of correlation from 1994 to 1997 between the A H3N2 component of the influenza vaccine recommended for this period and the circulating viruses in Argentina, we decided to study the antigenic and genomic relationships of the 1998 A H3N2 Argentine circulating strains with the corresponding vaccine component for that year as recommended by
A V, Pontoriero, E G, Baumeister, A M, Campos, V L, Savy, Y P, Lin, A J, Hay   +5 more
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Febrile Maculopapular Exanthem Associated with Influenza a Subtype H3N2 Viral Infection: A Rare Manifestation and a Review of the Literature

Acta Medica Bulgarica
Background: Influenza A-associated cutaneous manifestations are rare in adults and are poorly characterized, especially in infections, due to seasonal H3N2 strains. Awareness of influenza-related exanthems is clinically important because misdiagnosis may
Koyutourk B., Direnç E., Ergören M., Süer H.   +3 more
doaj   +1 more source

The V223I substitution in hemagglutinin reduces the binding affinity to human-type receptors while enhancing the thermal stability of the H3N2 canine influenza virus

Frontiers in Microbiology
Given the intimate relationship between humans and dogs, the H3N2 canine influenza viruses (CIVs) pose a threat to public health. In our study, we isolated four H3N2 CIVs from 3,758 dog nasal swabs in China between 2018 and 2020, followed by genetic and ...
Liling Liu, Fujun Wang, Fujun Wang, Ying Wu, Weiyong Mi, Yaping Zhang, Lei Chen, Dongxue Wang, Guohua Deng, Jianzhong Shi, Hualan Chen, Huihui Kong   +11 more
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The order of infection shapes disease outcomes in influenza and herpes simplex virus coinfection by modulating immune responses

Virology Journal
Background Coinfections of influenza A virus (IAV) and herpes simplex virus type 1 (HSV-1) have been increasingly reported in patients with severe pneumonia, yet their pathogenesis remains poorly understood.
Yuanjun Lyu, Kailin Mai, Hongxuan Zhou, Chunguang Yang, Yunceng Weng, Zhenhui Zhang, Yang Wang, Zifeng Yang   +7 more
doaj   +1 more source

How virus migration and meteorological elements shape the seasonality of influenza a/H3N2: A case study in China

One Health
Recent global influenza resurgences, escalating to pandemics, emphasize the urgency for effective vaccinations. Despite their efficacy, vaccines offer limited protection against A/H3N2 variants.
Yilan Liao, Tong Zhao, Wei Du, Dayan Wang, Zhibin Peng, Shan Xue, Jianxing Yu, An Zhang, Hongyan Ren, Zhoupeng Ren, Geoge Fu Gao, Jinfeng Wang, Nils Christian Stenseth   +12 more
doaj   +1 more source

Intraseasonal Dynamics and Dominant Sequences in H3N2 Influenza

PLoS ONE, 2010
Long-term influenza evolution has been well studied, but the patterns of sequence diversity within seasons are less clear. H3N2 influenza genomes sampled from New York State over ten years indicated intraseasonal changes in evolutionary dynamics. Using the mean Hamming distance of a set of amino acid or nucleotide sequences as an indicator of its ...
Nicole Creanza, Jason S Schwarz, Joel E Cohen   +2 more
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Genetic content of Influenza H3N2 vaccine seeds

PLoS Currents, 2010
Influenza vaccine seeds produced in chicken eggs are selected through HA and NA surface glycoproteins antigenicity, as well as through high replicative ability. Here we characterize the genetic content of recently used thirteen H3N2 influenza vaccine seeds.
Bergeron, Corinne, Valette, Martine, Lina, Bruno, Ottmann, Michele   +3 more
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Dynamic adaptation mutations and pathogenic characterization of a mouse-adapted seasonal human H3N2 influenza virus

Virology Journal
Background H3N2 influenza A viruses [A(H3N2)] circulate as seasonal influenza in humans worldwide, resulting in a huge disease burden. Adaptation study of A(H3N2) in mice could provide a basis for preclinical evaluation of antivirals and vaccines ...
Cheng Zhang, Yan Li, Ning Zhang, Ju Sun, Deyu Tian, Xuefeng Duan, Jing Yang, Yuhai Bi   +7 more
doaj   +1 more source