Results 61 to 70 of about 2,356 (118)

Synergistic effects of PA (S184N) and PB2 (E627K) mutations on the increased pathogenicity of H3N2 canine influenza virus infections in mice and dogs

Journal of Virology
As companion animals, dogs are susceptible to various subtypes of influenza A virus (IAV), with the H3N2 and H3N8 subtypes of canine influenza virus (CIV) stably circulating among canines.
Xiangyu Xiao, Xinrui Wang, Fengpei Xu, Yanting Liang, Yi Luo, Shoujun Li, Pei Zhou   +6 more
doaj   +1 more source

Lower cellular immune responses to influenza A (H3N2) in the elderly

Journal of Medical Virology, 2009
AbstractInfluenza epidemic is an important cause of severe illness in the elderly. Age‐dependent morbidity of influenza in the elderly is associated with weakened immunity. The baseline age‐related memory T cell activity in Chinese persons who are exposed to influenza virus through natural infection, are associated with the protective response to the ...
Jia, N, Li, C, Liu, Y, Richardus, J, Feng, D, Yang, H, Dang, R, Ma, Y, Xu, X, Cao, W   +9 more
openaire   +2 more sources

Efficacy and Safety in Dogs Following Administration of an Alphavirus RNA Particle Canine Influenza H3N2 Vaccine

Vaccines
Canine influenza virus (CIV) H3N2 causes a highly contagious respiratory disease in dogs and has been the source of outbreaks across North America since 2015.
Haley M. Classe, Jennifer C. Dant, Mark Mogler, Kenneth A. Stachura, Rhonda L. LaFleur, Zach Xu, Ian Tarpey   +6 more
doaj   +1 more source

Low population serum microneutralization antibody titer against the predominating influenza A(H3N2) N121K virus during the severe influenza summer peak of Hong Kong in 2017

Emerging Microbes and Infections, 2018
The 2017 Hong Kong influenza A(H3N2) summer season was unexpectedly severe. However, antigenic characterization of the 2017 circulating A(H3N2) viruses using ferret antisera did not show significant antigenic drift.
Houshun Zhu, Andrew C. Y. Lee, Can Li, Winger W. N. Mak, Yetta Y. Chen, Kwok-Hung Chan, Anna J. X. Zhang, Wai-Fong Fung, Rui-Qi Zhang, Yim-Fong Fung, Rosana W. S. Poon, Joy-Yan Lam, Sidney Tam, Ivan F. N. Hung, Honglin Chen, Kwok-Yung Yuen, Kelvin K. W. To   +16 more
doaj   +1 more source

Chronology of H3N2 human influenza virus surface glycoprotein adaptation from 1968 to 2019 reveals a surge of adaptation between 1997 and 2002

Journal of Virology
Subtype H3N2 influenza A viruses (IAVs), which emerged in 1968 to cause a pandemic, have shown continual circulation and adaptation that has necessitated frequent updates of candidate vaccine viruses.
Hui Lei, Biying Xiao, Xia Lin, Zaolan Liang, Shiman Ling, Yaqin Bai, Vijaykrishna Dhanasekaran, Wenjun Song, Sook-San Wong, Mark Zanin   +9 more
doaj   +1 more source

Novel introductions of human-origin H3N2 influenza viruses in swine, Chile

Frontiers in Veterinary Science
Influenza A virus (IAV) continuously threatens animal and public health globally, with swine serving as a crucial reservoir for viral reassortment and evolution.
Belen Monserrat Agüero, Naomi Ariyama, Felipe Berrios, Nikita Enciso, Barbara Quezada, Rafael A. Medina, Rafael A. Medina, Victor Neira, Victor Neira   +8 more
doaj   +1 more source

Genetic characterization of an H3N2 canine influenza virus strain in China in 2023—acquisition of novel human-like amino acid substitutions

Frontiers in Veterinary Science
Around 2005, influenza A virus (IAV) once again crossed species barriers and established a stable lineage within canine populations. Currently, avian-origin H3N2 canine influenza virus (CIV) is the only strain of influenza that is stably circulating in ...
Sihan Li, Liangyu Chu, Yancheng Zhang, Yaxuan Yu, Guoqing Wang   +4 more
doaj   +1 more source

Emergence of Novel Reassortant H3N2 Avian Influenza Viruses in Southern China: Genetic Complexity and Pathogenicity in Chickens and Mice

Animals
H3N2 subtype avian influenza virus (AIV) is prevalent in poultry and wild birds and typically causes asymptomatic or mild respiratory infections. However, genetic reassortment between H3N2 and other AIV subtypes generates novel strains capable of ...
Meichi Chen, Yanjiao Liang, Changmao Jian, Changting Li, Junwei Yang, Jingting Yang, Kewei Chen, Miaoxiang Zhang, Meilan Mo, Tianchao Wei, Teng Huang, Jianni Huang   +11 more
doaj   +1 more source

Study of the driving factors of the abnormal influenza A (H3N2) epidemic in 2022 and early predictions in Xiamen, China

BMC Infectious Diseases
Background Influenza outbreaks have occurred frequently these years, especially in the summer of 2022 when the number of influenza cases in southern provinces of China increased abnormally.
Hansong Zhu, Feifei Qi, Xiaoying Wang, Yanhua Zhang, Fangjingwei Chen, Zhikun Cai, Yuyan Chen, Kaizhi Chen, Hongbin Chen, Zhonghang Xie, Guangmin Chen, Xiaoyuan Zhang, Xu Han, Shenggen Wu, Si Chen, Yuying Fu, Fei He, Yuwei Weng, Jianming Ou   +18 more
doaj   +1 more source

Genetic characteristics of influenza A/H3N2 virus in Jiaxing, China (2019–2024)

Virology Journal
The rapid evolution of influenza A/H3N2 virus underscores the imperative for ongoing surveillance. In this study, we analyzed 7,872 respiratory samples collected from patients with influenza-like symptoms in Jiaxing, China, between 2019 and 2024 ...
Yin Song, Xue Zhang, Jimei Ji, Lina Li, Yamei Zhou, Ping Li, Ganglin Ren, Shencong Lv, Xiaofei Zhang, Yong Yan, Guoying Zhu   +10 more
doaj   +1 more source