Results 81 to 90 of about 38,283 (218)
Engineering Antibodies into Targeted Chimeras: From Recognition Modules to Programmable Degraders
Antibody can be engineered into diverse lysosome‐targeting chimeras that convert target recognition into active degradation. By coupling antibody binding with recruited receptors, encoded domains, conjugated ligands, or nanoparticle scaffolds, these antibody‐associated targeted chimeras (AbTACs) platforms direct extracellular and membrane proteins ...
Kaige Chen, Quanyin Hu
wiley +1 more source
Background and Objective: The emergence of a novel H1N1influenza A virus of animal origin with transmissibility from human to human poses pandemic concern.
S Zhand +7 more
doaj
Marginal posterior parameter estimates—H3N2 seasons.
Marginal posterior parameter estimates—H3N2 seasons.
Robert C. Cope (1807423) +4 more
core +1 more source
Background: Influenza A-associated cutaneous manifestations are rare in adults and are poorly characterized, especially in infections, due to seasonal H3N2 strains. Awareness of influenza-related exanthems is clinically important because misdiagnosis may
Koyutourk B. +3 more
doaj +1 more source
Given the intimate relationship between humans and dogs, the H3N2 canine influenza viruses (CIVs) pose a threat to public health. In our study, we isolated four H3N2 CIVs from 3,758 dog nasal swabs in China between 2018 and 2020, followed by genetic and ...
Liling Liu +11 more
doaj +1 more source
Some Exposure for Influenza Hemagglutinin Interface Antibodies
ABSTRACT Influenza viruses are a constant threat to human health. Current vaccines often confer low to moderate protection against infection with seasonal viruses and little‐to‐no protection against pandemic viruses. Improved vaccines are needed. These vaccines will need to reliably elicit antibodies to conserved sites that are broadly protective.
Kevin R. McCarthy
wiley +1 more source
Emergence and Fixing of Antiviral Resistance in Influenza A Via Recombination and Hitch Hiking [PDF]
The dramatic rise of oseltamivir resistance in the H1N1 serotype in the 2007/2008 season and the fixing of H274Y in the 2008/2009 season has raised concerns regarding individuals at risk for seasonal influenza, as well as development of similar ...
Henry L. Niman
core
Tab-delimited text file giving sequence accession numbers for seasonal A/H3N2 influenza viruses isolated between 1968 and 2011. Sequences come from both the Influenza Research Database (http://www.fludb.org/) and the EpiFlu Database that is part of ...
Gytis Dudas (3260436) +9 more
core +1 more source
Phylogenetic trees - Human H3N2 gene segment trees
Phylogenetic trees corresponding to nucleotide sequences of gene segments in human H3N2 viruses. Data are written in Newick format.
Seema Lakdawala (7816838) +1 more
core +1 more source
Predicting Antigenic Variants of Influenza A/H3N2 Viruses
Current inactivated influenza vaccines provide protection when vaccine antigens and circulating viruses share a high degree of similarity in hemagglutinin protein. Five antigenic sites in the hemagglutinin protein have been proposed, and 131 amino acid positions have been identified in the five antigenic sites.
Min-Shi Lee, Jack Si-En Chen
openaire +3 more sources

