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Influenza Vaccine Effectiveness: Defining the H3N2 Problem
AbstractObservational studies have consistently shown that influenza vaccine effectiveness (VE) is lower for H3N2 relative to H1N1pdm09 and type B, and this is not entirely explained by antigenic match. The triad of virus, vaccine, and host immunity provides a framework to examine contributing factors. Antigenic evolution facilitates H3N2 immune escape,
Edward Belongia +2 more
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A Review on H3N2 Influenza Virus
Asian Journal of Pharmaceutical Research, 2023The aim of this review is to discuss the influenza A i.e H3N2 influenza virus with their characteristics. Here we present the outline of the treatment regarding the H3N2 infection, precautions to be taken. The review focused on the symptoms and prevention of H3N2 influenza virus infection.
Dnyanda Kangude, S. D. Mankar
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The possible origin of H3N2 influenza virus
Virology, 1982Abstract The origin of H3N2 influenza virus was studied by T1 oligonucleotide mapping of RNA. H2N2 virus strains isolated during the 1967–1968 period had common oligonucleotides which were not found in the virus strains prevalent in 1965 or earlier but were conserved in the early H3N2 virus strain, A/Aichi/2/68.
K, Nakajima, S, Nakajima, A, Sugiura
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Influenza H3N2 Vaccines: Recent Challenges
Trends in Microbiology, 2018H3N2-subtype influenza A viruses are major causes of seasonal influenza epidemics. Emerging H3N2 variants require the annual adjustment of the vaccine strain. Recently, studies addressing the reduced effectiveness of current H3N2 vaccines have identified production-related substitutions in the viral hemagglutinin antigen as a possible cause for reduced
Ahmed, Mostafa, Stephan, Pleschka
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H3N2 Influenza Virus: Is it Pandemic?
A and V Pub International Journal of Nursing and Medical Research, 2023The H3N2 subtype evolved from H2N2 virus and caused the pandemic in 1968-69 in Hong Kong. A total of 293 patients with influenza like illness were investigated during the course of continuous surveillance on influenza in Pune, India in 2000. The throat/nasal swab specimens collected from these patients were inoculated in MDCK cell culture and influenza
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The Global Circulation of Seasonal Influenza A (H3N2) Viruses
Science, 2008Antigenic and genetic analysis of the hemagglutinin of â¼13,000 human influenza A (H3N2) viruses from six continents during 2002â2007 revealed that there was continuous circulation in east and Southeast Asia (E-SE Asia) via a region-wide network of temporally overlapping epidemics and that epidemics in the temperate regions were seeded from this ...
Russell, CA +27 more
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The Resurgence of H3N2 in India: Is it Life-threatening?
Current Drug Targets, 2023Sonakshi Garg +2 more
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DIFFERING VIRULENCE OF H1N1 AND H3N2 INFLUENZA STRAINS
American Journal of Epidemiology, 1980Sequential influenza A/Texas/77 (H3N2) and A/USSR/77 (H1N1) epidemics occurred during the winter of 1977-1978 in two populations under viral surveillance for influenza. In college students who reported to the Vanderbilt student health service, roughly equivalent amounts of typical influenzal disease were documented by virus isolation and total health ...
P F, Wright, J, Thompson, D T, Karzon
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Poster: H3N2 influenza vaccine: A historical perspective
2011 IEEE 1st International Conference on Computational Advances in Bio and Medical Sciences (ICCABS), 2011We analyzed the dN/dS ratios of the vaccine strains against the immuno-escape mutant strain circulatings. Our preliminary analysis suggested the following: (1) Using graphical technique (see figure), we use sites (blue) with highest dN/dS ratios within the hyper-variable regions (red) (sites 100–200) of each flu season plotted against vaccine ...
Ham Ching Lam +2 more
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Simply influenza A (H3N2)-associated encephalitis with seizure
The American Journal of Emergency Medicine, 2019Influenza-associated acute encephalopathy (IAE) is more prevalent in children than in adults and often results in neurological sequelae or even death. Diagnosis of IAE is difficult as clinical presentation varies significantly and the influenza virus is rarely detected in cerebrospinal fluid.
Hao-Tang Yuan +5 more
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