Results 91 to 100 of about 52,761 (267)

Marginal posterior parameter estimates—H3N2 seasons.

, 2018
Marginal posterior parameter estimates—H3N2 seasons.
Robert C. Cope (1807423), Nigel P. Stocks (5637962), Monique Chilver (5637959), Lewis Mitchell (416253), Joshua V. Ross (251593)   +4 more
core   +1 more source

Glycan remodeled erythrocytes facilitate antigenic characterization of recent A/H3N2 influenza viruses

Nature Communications, 2020
During circulation in humans and natural selection to escape antibody recognition for decades, A/H3N2 influenza viruses emerged with altered receptor specificities.
Frederik Broszeit, R. J. van Beek, Luca Unione, T. Bestebroer, Digantkumar G. Chapla, Jeong-Yeh Yang, K. Moremen, S. Herfst, R. Fouchier, R. de Vries, G. Boons   +10 more
semanticscholar   +1 more source

Dual Host–Pathogen Screening of the Lung During Severe Influenza Using Spatial Transcriptomics

Immunology &Cell Biology, EarlyView.
We performed genome‐wide spatial transcriptomics at 10 μm resolution on the lungs of mice infected with influenza A virus. We utilised publicly available scRNAseq reference datasets to identify cell types present. We found viral transcripts across all detected cell types, suggesting localised indiscriminate infection.
Marcus Z. W. Tong, Oliver P. Skinner, Chen Zhu, Brooke J. Wanrooy, Ashlyn S. Kerr, Zheng Ruan, Cameron G. Williams, Heran Zhang, Linda M. Wakim, Ashraful Haque   +9 more
wiley   +1 more source

Simultaneous co-infection with swine influenza A and porcine reproductive and respiratory syndrome viruses potentiates adaptive immune responses

Frontiers in Immunology, 2023
Porcine respiratory disease is multifactorial and most commonly involves pathogen co-infections. Major contributors include swine influenza A (swIAV) and porcine reproductive and respiratory syndrome (PRRSV) viruses.
Tiphany Chrun, Emmanuel A. Maze, Kelly J. Roper, Eleni Vatzia, Basudev Paudyal, Adam McNee, Veronica Martini, Tanuja Manjegowda, Graham Freimanis, Adrian Silesian, Noemi Polo, Becky Clark, Emily Besell, Georges Booth, Brigid Veronica Carr, Matthew Edmans, Alejandro Nunez, Surapong Koonpaew, Nanchaya Wanasen, Simon P. Graham, Elma Tchilian   +20 more
doaj   +1 more source

Neuraminidase antigenic drift of H3N2 clade 3c.2a viruses alters virus replication, enzymatic activity and inhibitory antibody binding

PLoS Pathogens, 2020
In the 2014–2015 influenza season a novel neuraminidase (NA) genotype was detected in global human influenza A surveillance. This novel genotype encoded an N-linked glycosylation site at position 245–247 in the NA protein from clade 3c.2a H3N2 viruses ...
Harrison Powell, A. Pekosz
semanticscholar   +1 more source

Influenza A Virus at the Exhibition Swine‐Human Interface in the USA

Zoonoses and Public Health, EarlyView.
ABSTRACT Introduction In the USA, zoonotic influenza A virus (IAV) transmission occurs frequently in youth who exhibit swine at agricultural competitions, presenting an ongoing pandemic risk. However, active surveillance in this high‐risk human population is lacking.
Dillon S. McBride, Martha I. Nelson, Hannah J. Cochran, Heather N. Nicholson, Elizabeth M. Ohl, Yunho Jang, Natosha Zanders, Dan Cui, Han Di, C. Todd Davis, John R. Barnes, Malania M. Wilson, Marie K. Kirby, Andrew S. Bowman, Jacqueline M. Nolting   +14 more
wiley   +1 more source

Sequence data and metadata for H3N2

, 2015
Geographic, temporal and sequence data for ...
Xiyan Xu (311040), Eugene Skepner (3243870), Alexander Klimov (270051), Masato Tashiro (247574), Colin A. Russell (23028), Nancy J. Cox (47093), Mandeep Chadha (336230), Derek J. Smith (247972), Marc A. Suchard (36176), John W. McCauley (263271), Trevor Bedford (376961), Yuelong Shu (132243), Andrew Rambaut (15183), C. Palani Gunasekaran (3243864), Ian G. Barr (216006), Xiyan Li (840783), Nicola S. Lewis (389210), Aeron C. Hurt (215989), Shobha Broor (30272), Steven Riley (31524), Varsha Potdar (3243867), Anne Kelso (411596), Philippe Lemey (30422), Dayan Wang (349634), Takato Odagiri (247568), Rodney S. Daniels (3174885)   +25 more
core   +1 more source

Ineffectiveness of the 2014-2015 H3N2 influenza vaccine

Oncotarget, 2015
The seasonal influenza vaccine is currently the most effective preventive modality against influenza infection. Nasopharyngeal samples of vaccinated and non-vaccinated patients presenting with Influenza-like-illness (ILI) were collected from over 20 outpatient clinics located in different geographic parts of Israel and were tested for the presence of ...
Michal, Mandelboim, Aharona, Glatman-Freedman, Yaron, Drori, Hilda, Sherbany, Rakefet, Pando, Hanna, Sefty, Hila, Zadka, Tamar, Shohat, Nathan, Keller, Ella, Mendelson   +9 more
openaire   +3 more sources

Predominance of a Drifted Influenza A (H3N2) Clade and its Association with Age-specific Influenza Vaccine Effectiveness Variations, Influenza Season 2018–2019

Vaccines, 2020
Background: Influenza A (H3N2) clade 3C.3a was the predominant influenza virus in Israel throughout the 2018-2019 season, constituting a drift from the influenza A (H3N2) vaccine.
Aharona Glatman-Freedman, Rakefet Pando, Hanna Sefty, Itay Omer, Alina Rosenberg, Yaron Drori, Ital Nemet, Ella Mendelson, Lital Keinan-Boker, Michal Mandelboim, for the Israeli Influenza Surveillance Network (IISN)   +10 more
doaj   +1 more source

Canonical Antibodies Adopt Distinct Binding Modes to Recognize Viral Glycan Shields

Advanced Science, Volume 13, Issue 61, 3 November 2026.
Canonical Y‐shaped antibodies recognize viral glycan shields through adaptive Fab assembly states shaped by glycan organization and somatic hypermutation. Structural analyses ofbroadly neutralizing antibodies VRC35 and VRC36 across glycoproteins of HIV‐1, influenza, SARS‐CoV‐2, and Lassa viruses reveal distinct Fab assembly states, spanning monovalent,
Jiaxuan Cheng, Evan M. Cale, Amirabbas Maghsoudi, Matthew S. Sutton, Nancy S. Longo, Rebecca A. Gillespie, Lingshu Wang, Ivan Kosik, Sue Chong, Atsuhiro Yasuhara, Tatsiana Bylund, Arne Schön, Prabhanshu Tripathi, Yaroslav Tsybovsky, Haotian Lei, Nicholas C. Morano, Allison B. Lupatkin, Abraham J. Morton, Zabrina C. Lang, Jordan E. Becker, Isabella R. Frascilla, Myungjin Lee, Ning Li, Cuiping Liu, Ryan S. Roark, Chen‐Hsiang Shen, I‐Ting Teng, David J. Van Wazer, Danyi Wang, Lingyuan Wu, Goran Ahlsen, Mike Castro, Haijuan Du, Michael J. Ernandes, Tiansheng Li, Bob C. Lin, Mark K. Louder, Krisha McKee, Jonah S. Merriam, Sijy O'Dell, Li Ou, Sergei Pletnev, David Prikryl, Qi Qiu, Sarah Rubin, Mallika Sastry, Stephen D. Schmidt, Asif Shajahan, Andrea R. Shiakolas, Sanjay Srivatsan, Baoshan Zhang, Qiong Zhou, Mark Connors, Jason G. Gall, Yicheng Guo, Rick K. Huang, Yaoxing Huang, Richard A. Koup, Q. Paula Lei, John R. Mascola, Reda Rawi, Leonid Serebryannyy, Lawrence Shapiro, Zizhang Sheng, David D. Ho, Patrick C. Wilson, Jonathan W. Yewdell, Theodore C. Pierson, Masaru Kanekiyo, Nicole A. Doria‐Rose, Peter D. Kwong, Tongqing Zhou   +71 more
wiley   +1 more source