Results 31 to 40 of about 51,349 (223)

Natural co-infection of influenza A/H3N2 and A/H1N1pdm09 viruses resulting in a reassortant A/H3N2 virus

Journal of Clinical Virology, 2015
Despite annual co-circulation of different subtypes of seasonal influenza, co-infections between different viruses are rarely detected. These co-infections can result in the emergence of reassortant progeny.We document the detection of an influenza co-infection, between influenza A/H3N2 with A/H1N1pdm09 viruses, which occurred in a 3 year old male in ...
Rith, Sareth, Chin, Savuth, Sar, Borann, Y, Phalla, Horm, Srey Viseth, Ly, Sovann, Buchy, Philippe, Dussart, Philippe, Horwood, Paul F.   +8 more
openaire   +3 more sources

Antigenicity prediction and vaccine recommendation of human influenza virus A (H3N2) using convolutional neural networks

Human Vaccines & Immunotherapeutics, 2020
The rapid evolution of influenza A viruses poses a great challenge to vaccine development. Analytical and machine learning models have been applied to facilitate the process of antigenicity determination.
Eva K. Lee, Haozheng Tian, Helder I. Nakaya   +2 more
doaj   +1 more source

Potential mechanisms mediating PM2.5-induced alterations of H3N2 influenza virus infection and cytokine production in human bronchial epithelial cells

Ecotoxicology and Environmental Safety, 2023
Exposure to particulate matter (PM) has been associated with increased hospital admissions for influenza. Airway epithelial cells are a primary target for inhaled environmental insults including fine PM (PM2.5) and influenza viruses.
Yinbiao Wang, Rui Zhang, Fuyun Yang, Lin Yang, Qingmei Li, Junqing Guo, Xiao Liu, Jie Song, Guofu Zhang, Juan Li, Zhen An, Neil E. Alexis, Ilona Jaspers, Weidong Wu   +13 more
doaj   +1 more source

Integrating influenza antigenic dynamics with molecular evolution. [PDF]

, 2013
Influenza viruses undergo continual antigenic evolution allowing mutant viruses to evade host immunity acquired to previous virus strains. Antigenic phenotype is often assessed through pairwise measurement of cross-reactivity between influenza strains ...
Abed, Ansaldi, Ansaldi, Barr, Barr, Bedford, Bedford, Bogner, Borodin, Cai, Centers for Disease Control and Prevention, Chakraverty, Chakraverty, Cox, Cox, Daniels, Daum, Daum, Donatelli, Drummond, Edgar, Ferguson, Fitch, Gog, Goldstein, Gust, Hay, Hay, Hay, Hay, Hay, Hay, Hay, Hay, Hay, Hay, Hay, Hay, Hay, Hay, Hensley, Hirst, Kanegae, Kendal, Klimov, Koel, Lemey, Li, Lin, Lin, Lin, Lin, Matsuzaki, McCauley, McCauley, McCauley, McCauley, McCauley, McDonald, Muyanga, Nakagawa, Nakajima, Nakajima, Nakajima, Nelson, Nerome, Oh, Osterholm, Pagel, Pereira, Puzelli, Pybus, Raymond, Rota, Russell, Shapiro, Shaw, Smith, Squires, Stevens, Webster, Wiley, World Health Organization, Xu   +83 more
core   +4 more sources

Cross-protection against European swine influenza viruses in the context of infection immunity against the 2009 pandemic H1N1 virus : studies in the pig model of influenza [PDF]

, 2015
Pigs are natural hosts for the same influenza virus subtypes as humans and are a valuable model for cross-protection studies with influenza. In this study, we have used the pig model to examine the extent of virological protection between a) the 2009 ...
A Krumbholz, A Lavenu, AC Lowen, AI Karasin, AR Vleeschauwer De, AS Monto, B Brandenburg, B Manicassamy, B Srivastava, CD O’Donnell, CD O’Donnell, CS Kyriakis, CS Kyriakis, DM Skowronski, ED Kilbourne, G Simon, GA Landolt, GG Brownlee, I Skountzou, IH Brown, JC Kash, JH Kreijtz, JL Schulman, K Hoschler, K Reeth Van, K Reeth Van, K Reeth Van, K Reeth Van, K Tamura, Karl De hert, KL Laurie, Kristien Van Reeth, L Campitelli, M Khatri, M Pensaert, M Retamal, M Strengell, MA Marco De, MI Nelson, MJ Sylte, ML Hillaire, MR Castrucci, MR Castrucci, MR Sandbulte, N Busquets, NM Bouvier, PM Colman, PP Heinen, RA Perera, RA Yetter, RJ Garten, S Liang, SL Epstein, SM Brookes, T Sonoguchi, TM Straight, Y Qiu, Y Qiu, Yu Qiu   +58 more
core   +6 more sources

Rapport national de mi-saison sur l’influenza au Canada, 2019 à 2020

Canada Communicable Disease Report, 2020
Au Canada, la saison nationale de la grippe a commencé à la semaine 47, entre le 17 et le 23 novembre 2019. Des 3 762 détections des cas de grippe confirmées en laboratoire ayant été signalées entre le 25 août et le 14 décembre 2019, 61 % étaient de type
Claire Sevenhuysen, Liza Lee, Andrea Nwosu, Tiffany Smith, Lindsay Whitmore, Nathalie Bastien, Mireille Desroches, Christina Bancej   +7 more
doaj   +1 more source

Whole-genome sequences of two influenza A (H3N2) virus strains isolated from Qinghai, China

Biosafety and Health, 2021
Influenza A (H3N2) virus has a faster evolution rate than other types of influenza viruses. In this study, whole genome sequencing was performed to better understand the molecular evolution of influenza H3N2 and the protective effect of influenza virus ...
Juan Yu, Shengcang Zhao, Huaxiang Rao
doaj   +1 more source

Timescales of influenza A/H3N2 antibody dynamics

PLOS Biology, 2017
Abstract Human immunity influences the evolution and impact of novel influenza strains. Because individuals are infected with multiple influenza strains during their lifetime and each virus can generate a cross-reactive antibody response, it is challenging to quantify the processes that shape observed immune responses, or to reliably ...
Adam J. Kucharski, Justin Lessler, Derek A. T. Cummings, Steven Riley   +3 more
openaire   +5 more sources

Long-lasting cross-protection against influenza A by neuraminidase and M2e-based immunization strategies [PDF]

, 2016
There is mounting evidence that in the absence of neutralizing antibodies cross-reactive T cells provide protection against pandemic influenza viruses. Here, we compared protection and CD8+ T cell responses following challenge with H1N1 2009 pandemic and
Callewaert, Nico, Fiers, Walter, Saelens, Xavier, Schepens, Bert, Schotsaert, Michael, Smet, Anouk, Stegalkina, Svetlana, Vanderschaeghe, Dieter, Vogel, Thorsten U, Ysenbaert, Tine   +9 more
core   +2 more sources

H3N2 Emergence in India 

International Journal of Pediatrics and Child Health, 2015
Influenza a pandemic in 2009 was predominantly by H1N1strain, however in the current seasonal outbreak H3N2 is more prevalent in North America, Europe and Eastern Asia. However very few cases have been reported from India. We report a case of 5-year-old girl child with H3N2 infection with acute onset and rapid progression.
Smita Ramachandran, Rani Gera
openaire   +1 more source