Results 41 to 50 of about 1,178 (159)

Sepsis in Dogs and Cats—Consensus Definition and Clinical Criteria

Journal of Veterinary Emergency and Critical Care, EarlyView.
ABSTRACT Sepsis is the clinical syndrome that results from the host response to severe or widespread infection and is a frequent cause of death in veterinary critical care settings. Rapid diagnosis aids early treatment initiation, and hence, how sepsis is defined and identified clinically has implications for patient outcomes.
Robert Goggs, Stefano Cortellini, Amy E. DeClue, Massimo Giunti, Kate Hopper, Julie M. Menard, Rodrigo C. Rabelo, Elizabeth A. Rozanski, Claire R. Sharp, Deborah C. Silverstein, Virginia Sinnott‐Stutzman, Giacomo Stanzani, John Bourgeois, Erik Fausak   +13 more
wiley   +1 more source

Treatment of canine leishmaniosis: An update.

Journal of the Hellenic Veterinary Medical Society, 2018
The drugs, currently recommended in the treatment of canine leishmaniosis, include meglumine antimonate, allopurinol, paromomycin (aminosidine) and amphotericin B. With the exception of meglumine antimonate, where an optimal dosage has been established (75 mg/Kg BW, every 12 hours, SC), that of allopurinol (10-20 mg/Kg, BW BID, per os), paromomycin (5 ...
M. N. SARIDOMICHELAKIS (Μ. Ν. ΣΑΡΙΔΟΜΙΧΕΛΑΚΗΣ), A. F. KOUTINAS (Α.Φ. ΚΟΥΤΙΝΑΣ), M. E. MYLONAKIS (Μ.Ε. ΜΥΛΩΝΑΚΗΣ)   +2 more
openaire   +2 more sources

Insights on adaptive and innate immunity in canine leishmaniosis [PDF]

Parasitology, 2016
SUMMARYCanine leishmaniosis (CanL) is caused by the parasiteLeishmania infantumand is a systemic disease, which can present with variable clinical signs, and clinicopathological abnormalities. Clinical manifestations can range from subclinical infection to very severe systemic disease.
Hosein, Shazia, Blake, Damer P., Solano Gallego, Laia Maria   +2 more
openaire   +5 more sources

Updated Canine Leishmaniosis Working Group recommendations for leishmaniosis in dogs: Q&A on clinical management

Parasites & Vectors
Canine leishmaniosis is an important vector-borne disease and a threat to dogs worldwide. Disease data are continuously being collected, with a consequent increase in the number of publications.
Xavier Roura, Saverio Paltrinieri, Oscar Cortadellas, Alessandra Fondati, George Lubas, Eric Zini, Domenico Otranto, Silvia Lucia Benali, Andrea Zatelli   +8 more
doaj   +1 more source

Canine Leishmaniosis in Italy: Geospatial Trends and Incidence, a Shift in Epidemiological Approach

Zoonoses and Public Health, EarlyView.
ABSTRACT Introduction Canine leishmaniosis (CanL) has shown a marked geographic expansion in Italy, progressively affecting central and northern regions previously considered non‐endemic. Laboratory‐based prevalence estimates remain informative in well‐designed surveys; however, prevalence derived from diagnostic submissions may be influenced by study ...
Federica Bruno, Germano Castelli, Eugenia Oliveri, Gaetano Oliva, Mariele De Santi, Claudia La Rocca, Ornella Melideo, Marco Ripamonti, Francesco La Russa, Maria Liliana Di Pasquale, Antonella Galante, Roberto Hamel, Giorgio Schiera, Marzio Cometa, Silvia Scibetta, Stefano Reale, Fabrizio Vitale   +16 more
wiley   +1 more source

Borrelia, Leishmania, and Babesia: An Emerging Triad of Vector-Borne Co-Infections?

Pathogens
Canine leishmaniosis (CanL), caused by the protozoan Leishmania infantum and transmitted primarily by phlebotomine sand flies, poses significant challenges for zoonotic disease management [...]
Elianne Piloto-Sardiñas, Ana Laura Cano-Argüelles, Alejandro Cabezas-Cruz   +2 more
doaj   +1 more source

Structural basis of ligand selectivity in FAD/NAD(P)H‐dependent dehydrogenases: insights from trypanothione reductase and type II NADH dehydrogenase

Protein Science, Volume 35, Issue 7, July 2026.
Abstract FAD/NAD(P)H‐dependent dehydrogenases form a structurally conserved family of redox enzymes that participate in essential metabolic processes across parasites and higher organisms. Among them, trypanothione reductase (TR) is a key component of the redox metabolism of Leishmania species and represents an attractive target for antileishmanial ...
Giulia Chiara Maria Perrone, Serena Spadone, Anna Lucia Francavilla, Sara Morselli, Sabino Todisco, Margherita Ortalli, Jairo Alfonso Mendoza‐Roldan, Valeria Scaglione, Maria Noemi Sgobba, Lorenzo Guerra, Federica Belluti, Stefania Varani, Domenico Otranto, Anna De Grassi, Mariateresa Volpicella, Ciro Leonardo Pierri   +15 more
wiley   +1 more source

Evaluation of the Cutaneous Immunological Milieu Before and After Treatment With Meglumine Antimoniate in Dogs Naturally Affected by Leishmaniosis due to Leishmania infantum

Veterinary Dermatology, Volume 37, Issue 3, Page 455-463, June 2026.
Background: Canine leishmaniosis (CanL) is a zoonotic disease of variable severity. The typical immune response is driven by an exaggerated humoral immune response. Protective immunity is mediated by pro‐inflammatory cytokines that enhance macrophage leishmanicidal activity. Objective: To evaluate the cutaneous and the systemic immune responses as well
M. Platenik, A. Di Loria, L. Archer, M. Saridomichelakis, A. S. Benvenuto, D. Santoro   +5 more
wiley   +1 more source

Leishmaniosis due to Leishmania infantum in a FIV and FeIV positive cat with a squamous cell carcinoma diagnosed with histological, serological and isoenzymatic methods

Parasite, 2005
Leishmaniosis caused by Leishmania infantum is an endemic zoonosis present in the Mediterranean area. Canidae (dog and fox) constitute the main reservoir hosts for the parasite, whilst wild rodents or the cat can be carriers of the protozoan and are ...
Grevot A., Jaussaud Hugues P., Marty P., Pratlong F., Ozon C., Haas P., Breton C., Bourdoiseau G.   +7 more
doaj   +1 more source

Canine chronic idiopathic rhinitis: management and outcome – a single‐centre retrospective observational study

Journal of Small Animal Practice, Volume 67, Issue 5, Page 460-470, May 2026.
Objectives Canine chronic idiopathic rhinitis is a common cause of nasal disease in dogs but data reporting outcomes following treatment is lacking. The aim was to describe pre‐ and post‐referral management and outcomes of dogs diagnosed with canine chronic idiopathic rhinitis at a single referral centre.
P. M. N. Henry, R. Rizzo, Y. Tan, A. M. Boag, J. Del‐Pozo, G. A. Woods   +5 more
wiley   +1 more source