Results 101 to 110 of about 343,983 (293)

Cannabis‐Based Oil for Pain and Other Non‐Motor Symptoms in Parkinson's Disease: A Randomized Controlled Trial

Movement Disorders, EarlyView.
Abstract Background There is a lack of treatments for non‐motor symptoms (NMS) in Parkinson's disease (PD). Objective To assess the safety and effectiveness of an oral Cannabis sativa L. extract on pain and other NMS of PD. Methods This phase II, randomized, placebo‐controlled trial evaluated a formulation containing cannabidiol (CBD; 96 mg/ml) and Δ9 ...
Gabriel T. Kubota, Jacy B. Parmera, Matheus Deltreggia, Pedro N. Martins, Anna Letícia M. Alves, Ananda C.M. de Falcone, Ana Rosa Santana, Maria Alice P. Falcão, Mayara A. Dias, Larissa I. Moreira, Paulo C. de Fonseca Filho, Eberval G. Figueiredo, Egberto R. Barbosa, Rubens G. Cury, Daniel C. de Andrade   +14 more
wiley   +1 more source

The case for medicinal cannabis [PDF]

Irish Journal of Medical Science (1971 -), 2018
Jane, O'Doherty, Ray, O'Connor
openaire   +2 more sources

Advancing Therapies for Mycobacterial Diseases: From Small Molecules to Host‐Directed Strategies

Medicinal Research Reviews, EarlyView.
ABSTRACT The global burden of multidrug‐resistant tuberculosis (MDR‐TB) and the rising incidence of nontuberculous mycobacterial (NTM) infections highlight the urgent need for innovative therapeutic strategies. Current treatments are prolonged, toxic, and increasingly compromised by resistance and limited diagnostic capacity.
Tânia Silva, Alessandra Aiello, Tonino Alonzi, M. Alice Carvalho, Vladimir Finger, Delia Goletti, Sven Hoffner, Yousra Kherabi, Jan Korabecny, Julia Kulczyńska, Agnieszka Kyzioł, Alicia Lacoma, Filomena Martins, Zorica Nanovic, Sepideh Hosseiniporgham, Martina Hrast Rambaher, Leonardo Antonio Sechi, Daria Smalchuk, Grażyna Stochel, Lydia Tabernero, Nancy L. Tateosian, Violeta Valcheva, Anamarija Zega, Mafalda Sarraguça   +23 more
wiley   +1 more source

Use of medicinal cannabis in dogs with multicentric lymphoma: a report of two cases [PDF]

Arquivo Brasileiro de Medicina Veterinária e Zootecnia
Multicentric lymphoma is the most common hematopoietic neoplasia in dogs, with chemotherapy being the standard treatment. Medicinal cannabis, especially cannabidiol (CBD), has been studied as a complementary therapy to mitigate symptoms and adverse ...
B.A. Teixeira, C. Mariga, S.R. Feltrin, K.M. Marques, A.Q. Antoniazzi, C.M. Andrade, S.T.L. Pinto Filho   +6 more
doaj   +1 more source

Developing the Dopamine D3 Receptor (D3R) Antagonist, (R)‐VK4‐116, as a Non‐Opioid Medication for the Treatment of Opioid Use Disorder

Medicinal Research Reviews, EarlyView.
ABSTRACT Opioid use disorder (OUD) remains a major global health challenge, and currently approved treatments (methadone, buprenorphine, and naltrexone) are all opioid receptor‐targeting drugs with limitations in access, adherence, stigma, and use in polysubstance use disorders. Because the dopamine D3 receptor (D3R) is enriched in limbic brain regions
Chia‐Kuei Wu, Yu‐Chih Lin, Junfeng Huang, Bangwei Ding, Pramod Terse, Rahul Nandre, Haksong Jin, Molly Congdon, Kun Shen, Philip Sanderson, Gregory Tawa, Stephanie Mounaud, Marta De Santis, Donald Lo, Elizabeth A. Ottinger, Amy Hauck Newman   +15 more
wiley   +1 more source

Efficacy and Safety of Cannabis Derivates and Their Synthetic Analogs. Overview of Systematic Reviews

Phytotherapy Research, EarlyView.
ABSTRACT The use of medicinal products derived from cannabis and its synthetic analogues has grown in recent years for various health conditions, which led to an increase in systematic reviews (SR) on the topic. The objective of this overview was to identify, synthesize, and critically appraise the evidence from SR on the benefits and harms of cannabis
Rafael Leite Pacheco, Daniela Fortunato Rêgo, Carolina de Oliveira Cruz Latorraca, Marco Aurelio de Carvalho Nascimento, André Bastos Daher, Rachel Riera   +5 more
wiley   +1 more source

Plant‐Derived Extracellular Vesicles: Biogenesis, Function, and Application in Cancer Immunotherapy

Phytotherapy Research, EarlyView.
This illustration shows the biogenesis pathways of edible and medicinal plant‐derived extracellular vesicles (PDEVs) and their therapeutic effects following uptake in the human body, highlighting their potential for application in cancer immunotherapy. ABSTRACT Plant‐derived extracellular vesicles (PDEVs) are nanoscale, lipid bilayer‐enclosed vesicles ...
Guosheng Li, Mengyu Li, Shujing Liu, Yuan Wei, Chen Wang   +4 more
wiley   +1 more source

Prohibited Plants: Converging Sustainability Transitions and Local Development in ‘Left‐Behind Places’

Sustainable Development, EarlyView.
ABSTRACT This paper examines the relationship between sustainability transitions and local development through the case of Colombia's medicinal cannabis industry. It highlights how neglecting place‐specific needs and development expectations can hinder equitable transitions and reinforce existing socio‐economic disparities.
Diana Morales, Mónica Ramos‐Mejía
wiley   +1 more source

Health professional beliefs, knowledge, and concerns surrounding medicinal cannabis - A systematic review.

PLoS ONE, 2019
BackgroundThe number of jurisdictions allowing access to medicinal cannabis has been steadily increasing since the state of California introduced legislation in 1996.
Kyle M Gardiner, Judith A Singleton, Janie Sheridan, Gregory J Kyle, Lisa M Nissen   +4 more
doaj   +1 more source

Performing Integrity: Managing Misalignment while Researching Transgressive Social Worlds

Symbolic Interaction, EarlyView.
The qualitative literature criticizing REBs suggests that researchers should develop an approach to research ethics that does justice to their daily practice of fieldwork. In this article, I contribute to this exploration by presenting three cases of negotiating research ethics while researching transgressive social worlds.
Thaddeus Müller
wiley   +1 more source