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Cannabinoids on the Brain [PDF]

The Scientific World Journal, 2002
Cannabis has a long history of consumption both for recreational and medicinal uses. Recently there have been significant advances in our understanding of how cannabis and related compounds (cannabinoids) affect the brain and this review addresses the ...
Andrew J. Irving, Mark G. Rae, Angela A. Coutts   +2 more
doaj   +6 more sources

Uncovering the molecular targets of phytocannabinoids: mechanistic insights from inverse molecular docking fingerprint approaches

Frontiers in Pharmacology
IntroductionAmong diverse chemical profile of Cannabis sativa L., over 100 phytocannabinoids have been identified. The major cannabinoids Δ-9-THC and CBD are well-studied, with approved palliative and therapeutic applications such as appetite stimulation,
Vid Ravnik, Marko Jukič, Marko Jukič, Veronika Furlan, Uroš Maver, Uroš Maver, Jan Rožanc, Urban Bren, Urban Bren, Urban Bren   +9 more
doaj   +1 more source

Cannabinoids—Multifunctional Compounds, Applications and Challenges—Mini Review

Molecules
Cannabinoids represent a highly researched group of plant-derived ingredients. The substantial investment of funds from state and commercial sources has facilitated a significant increase in knowledge about these ingredients.
Dominik Duczmal, Aleksandra Bazan-Wozniak, Krystyna Niedzielska, Robert Pietrzak   +3 more
doaj   +1 more source

The use of cannabinoids in animals and therapeutic implications for veterinary medicine: a review

Veterinární Medicína, 2016
Cannabinoids/medical marijuana and their possible therapeutic use have received increased attention in human medicine during the last years. This increased attention is also an issue for veterinarians because particularly companion animal owners now show
L. Landa, A. Sulcova, P. Gbelec
doaj   +1 more source

Optimization of the supercritical extraction and decarboxylation process of industrial hemp

Journal of CO2 Utilization
Cannabinoids are the main active ingredients of Cannabis sativa L., obtained by a suitable extraction method and decarboxylation, in which the acid forms of the cannabinoids are converted into active forms.
Taja Žitek Makoter, Petra Kotnik, Teo Makoter, Željko Knez, Maša Knez Marevci   +4 more
doaj   +1 more source

Exploring the therapeutic potential of cannabinoids in cancer by modulating signaling pathways and addressing clinical challenges

Discover Oncology
For centuries, cannabinoids have been utilized for their medicinal properties, particularly in Asian and South-Asian countries. Cannabis plants, known for their psychoactive and non-psychoactive potential, were historically used for spiritual and ...
Manal Bint Faiz, Faiza Naeem, Muhammad Irfan, Muhammad Adeel Aslam, Leticia M. Estevinho, Dilek Arslan Ateşşahin, Asma M. Alshahrani, Daniela Calina, Khushbukhat Khan, Javad Sharifi-Rad   +9 more
doaj   +1 more source

Exploring the Potential of Synthetic Cannabinoids: Modulation of Biological Activity of Normal and Cancerous Human Colon Epithelial Cells

Cells
Colorectal cancer (CRC) is a global problem. Oncology currently practices conventional methods of treating this carcinoma, including surgery, chemotherapy, and radiotherapy. Unfortunately, their efficacy is low; hence, the exploration of new therapies is
Roman Paduch, Katarzyna Szwaczko, Kamil Dziuba, Adrian Wiater   +3 more
doaj   +1 more source

CANNABINOIDS IN CLINICAL SEPSIS: A SCOPING REVIEW

Brazilian Journal of Infectious Diseases
Introduction: Sepsis is a severe disease with high mortality and a major public health challenge. Despite being studied for decades, its treatment remains limited to symptom management and clinical support.
Carolina Henkes Inamassu, Letícia Borges Nunes, Regina de Sordi, Camila Marchioni   +3 more
doaj   +1 more source

Evaluation of cannabis product mislabeling: The development of a unified cannabinoid LC-MS/MS method to analyze e-liquids and edible products

Talanta Open
The 2018 Agricultural Improvement Act federally legalized the cultivation of hemp and manufacture and sale of cannabidiol (CBD). The overproduction of CBD led to a significant drop in price.
Ashleigh E. Outhous, Alaina K. Holt, Justin L. Poklis, Michelle R. Peace   +3 more
doaj   +1 more source

Evaluation of Phytocannabinoids as Antitumor Agents against Ovarian Cancer Cells in Combination with Carboplatin. [PDF]

ACS Omega
Warter U, Yogev Y, Nwobodo DC, Lialin K, Mantin D, Meirovitz M, Meijler MM, Mayer A.   +7 more
europepmc   +1 more source