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Cannabis has a long history of consumption both for recreational and medicinal uses. Recently there have been significant advances in our understanding of how cannabis and related compounds (cannabinoids) affect the brain and this review addresses the ...
Andrew J. Irving +2 more
doaj +4 more sources
Cannabinoids, active components of the plant Cannabis sativa, had been used for centuries in ancient medicine as therapeutic remedies for a variety of conditions, before becoming stigmatized due to their psychoactive effects [...]
Marco Falasca, Mauro Maccarrone
openaire +2 more sources
Cannabinoids in Pediatrics [PDF]
Despite its controversial nature, the use of medical marijuana and cannabis-derived medicinal products grows more popular with each passing year. As of November 2016, over 40 states have passed legislation regarding the use of either medical marijuana or cannabidiol products. Many providers have started encountering patients experimenting with cannabis
Christopher T, Campbell +2 more
openaire +2 more sources
Cannabinoids and glaucoma [PDF]
Glaucoma is one of the leading causes of blindness in the world. In spite of the diverse therapeutic possibilities, new and better treatments for glaucoma are highly desirable. Cannabinoids effectively lower the intraocular pressure (IOP) and have neuroprotective actions. Thus, they could potentially be useful in the treatment of glaucoma.
Azuara-Blanco, A. +2 more
openaire +3 more sources
Cannabinoids and Epilepsy [PDF]
Cannabis has been used for centuries to treat seizures. Recent anecdotal reports, accumulating animal model data, and mechanistic insights have raised interest in cannabis-based antiepileptic therapies. In this study, we review current understanding of the endocannabinoid system, characterize the pro- and anticonvulsive effects of cannabinoids [e.g ...
Evan C, Rosenberg +3 more
openaire +2 more sources
Sex-dependent effects of in utero cannabinoid exposure on cortical function
Cannabinoids can cross the placenta, thus may interfere with fetal endocannabinoid signaling during neurodevelopment, causing long-lasting deficits.
Anissa Bara +11 more
doaj +1 more source
Endocannabinoid system and anticancer properties of cannabinoids [PDF]
Cannabinoids impact human body by binding to cannabinoids receptors (CB1 and CB2). The two main phytocannabinoids are Δ9-tetrahydrocannabinol (THC) and cannabidiol (CBD).
Nowak, Agnieszka +3 more
core +2 more sources
Cannabinoids Rescue Cocaine-Induced Seizures by Restoring Brain Glycine Receptor Dysfunction
Summary: Cannabinoids are reported to rescue cocaine-induced seizures (CISs), a severe complication in cocaine users. However, the molecular targets for cannabinoid therapy of CISs remain unclear.
Guichang Zou +15 more
doaj +1 more source
Cannabinoids in the Treatment of Epilepsy: A Review
Cannabinoids have been studied for their role in the treatment of epilepsy for many years. The U.S. Food and Drug Administration (FDA) approved them for the treatment of some refractory syndromes in 2018.
Daniel Zhou +3 more
doaj +1 more source
Detecting a signal in the noise : Monitoring the global spread of novel psychoactive substances using media and other open source information [PDF]
This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no ...
Canadian Community Epidemiology Network On Drug Use +3 more
core +1 more source

