Results 41 to 50 of about 64,716 (311)
Cannabinoids for epilepsy [PDF]
Cochrane Database of Systematic Reviews, 2011 Marijuana appears to have anti-epileptic effects in animals. It is not currently known if it is effective in patients with epilepsy. Some states in the United States of America have explicitly approved its use for epilepsy.To assess the efficacy of marijuana, or one of marijuana's constituents in the treatment of people with epilepsy.We searched the ...
David, Gloss, Barbara, Vickrey
openaire +3 more sources
Journal of Dermatological Treatment, 2022 Hyperhidrosis can significantly curtail patient quality of life, from debilitating physical symptoms to social stigmatization and reduced life opportunities. Current treatments often prove unsatisfactory, especially in sufferers of generalized hyperhidrosis.
Till Kaemmerer +4 more
openaire +3 more sources
The evolution and comparative neurobiology of endocannabinoid signalling [PDF]
, 2012 CB(1)- and CB(2)-type cannabinoid receptors mediate effects of the endocannabinoids 2-arachidonoylglycerol (2-AG) and anandamide in mammals. In canonical endocannabinoid-mediated synaptic plasticity, 2-AG is generated postsynaptically by diacylglycerol ...
Devane W. A. +4 more
core +1 more source
Pain Research and Management, 2001 Cannabinoids have been used to treat pain for many centuries. However, only during the past several decades have rigorous scientific methods been applied to understand the mechanisms of cannabinoid action. Cannabinoid receptors were discovered in the late 1980s and have been found to mediate the effects of cannabinoids on the nervous system.
J Michael Walker +2 more
openaire +3 more sources
Pharmacogenetics of Cannabinoids [PDF]
European Journal of Drug Metabolism and Pharmacokinetics, 2017 Although the application of medical marijuana and cannabinoid drugs is controversial, it is a part of modern-day medicine. The list of diseases in which cannabinoids are promoted as a treatment is constantly expanding. Cases of significant improvement in patients with a very poor prognosis of glioma or epilepsy have already been described. However, the
Hryhorowicz, Szymon +4 more
openaire +2 more sources
Medical Cannabis and Cannabinoids, 2022 Introduction: Acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) are two cholinergic enzymes catalyzing the reaction of cleaving acetylcholine into acetate and choline at the neuromuscular junction.
Tess Puopolo +3 more
doaj +1 more source
Cannabis sativa and the endogenous cannabinoid system: therapeutic potential for appetite regulation [PDF]
, 2011 The herb Cannabis sativa (C. sativa) has been used in China and on the Indian subcontinent for thousands of years as a medicine. However, since it was brought to the UK and then the rest of the western world in the late 19th century, its use has been a ...
Adams +215 more
core +3 more sources
Canadian Journal of Gastroenterology and Hepatology, 2009 Cannabinoid hyperemesis syndrome is characterized by chronic, heavy use of cannabis, recurrent episodes of severe nausea and intractable vomiting, and abdominal pain. Temporary relief of symptoms is achieved by taking a hot bath or shower, and resolution of the problem when cannabis use is stopped.
openaire +3 more sources
Cannabinoids as Key Regulators of Inflammasome Signaling: A Current Perspective
Frontiers in Immunology, 2021 Inflammasomes are cytoplasmic inflammatory signaling protein complexes that detect microbial materials, sterile inflammatory insults, and certain host-derived elements. Inflammasomes, once activated, promote caspase-1–mediated maturation and secretion of
Santosh V. Suryavanshi +2 more
doaj +1 more source
Phenotype-Based Screening of Synthetic Cannabinoids in a Dravet Syndrome Zebrafish Model. [PDF]
, 2020 Dravet syndrome is a catastrophic epilepsy of childhood, characterized by cognitive impairment, severe seizures, and increased risk for sudden unexplained death in epilepsy (SUDEP).
Anvar, Mana +3 more
core +1 more source