Results 51 to 60 of about 64,716 (311)

Cannabis; epidemiological, neurobiological and psychopathological issues: an update [PDF]

, 2017
This document is the Accepted Manuscript version of the following article: Maria Antonietta De Luca, Gaetano Di Chiara, Cristina Cadoni, Daniele Lecca, Laura Orsolini, Duccio Papanti, John Corkery, Fabrizio Schifano, 'Cannabis; Epidemiological ...
Cadoni, Cristina, Corkery, John, De Luca, Maria Antonietta, Di Chiara, Gaetano, Lecca, Daniele, Orsolini, Laura, Papanti, Duccio, Schifano, Fabrizio   +7 more
core   +3 more sources

Nightmares and the Cannabinoids [PDF]

Current Neuropharmacology, 2020
:The cannabinoids, Δ9 tetrahydrocannabinol and its analogue, nabilone, have been found to reliably attenuate the intensity and frequency of post-traumatic nightmares. This essay examines how a traumatic event is captured in the mind, after just a single exposure, and repeatedly replicated during the nights that follow.
openaire   +2 more sources

Semi-quantitative analysis of cannabinoids in hemp (Cannabis sativa L.) using gas chromatography coupled to mass spectrometry

Journal of Cannabis Research, 2022
Background Hemp (Cannabis sativa L.) is a producer of cannabinoids. These organic compounds are of increasing interest due to their potential applications in the medicinal field.
Luca De Prato, Matthew Timmins, Omid Ansari, Katinka X. Ruthrof, Giles E. St. J. Hardy, John Howieson, Graham O’Hara   +6 more
doaj   +1 more source

Discovery of orexant and anorexant agents with indazole scaffold endowed with peripheral antiedema activity [PDF]

, 2019
CB1 receptors and endocannabinoids are integrated components of neuronal networks controlling different organism’s functions, such as appetite and food intake in the hypothalamus.
Dimmito, Marilisa P., Dvorácskó, Szabolcs, MINOSI, PAOLA, MOLLICA, Adriano, PIERETTI, Stefano, Stefanucci, Azzurra, Tömböly, Csaba, Zengin, Gokhan   +7 more
core   +2 more sources

mGluR5 in ECCCK to BLA Circuit Modulates Depressive‐Like Phenotypes through CCK Signaling

Advanced Science, EarlyView.
Dysregulation of mGluR5 and CCK signaling contributes to major depressive disorder, yet circuit‐level mechanisms remain unclear. Here, the ECCCK→BLA pathway is identified as a critical regulator of affective behavior. mGluR5 modulates synaptic function and CCK signaling within this circuit, controlling stress susceptibility and depressive‐like states ...
Muhammad Asim, Huajie Wang, Gao Qianqian, Abdul Waris, Jufang He   +4 more
wiley   +1 more source

Genetic Background Can Result in a Marked or Minimal Effect of Gene Knockout (GPR55 and CB2 Receptor) in Experimental Autoimmune Encephalomyelitis Models of Multiple Sclerosis [PDF]

, 2013
PMCID ...
A Compston, A Shetty, A Zimmer, AC Howlett, AE Bygrave, C Bolton, C Delarasse, C Delarasse, C Teuscher, Carolyn Tanner, CS Wu, CS Wu, D Baker, D Baker, D Baker, D Baker, D Baker, D Baker, D Baker, D McHugh, David Baker, David L. Selwood, DL Smith-Bouvier, E de Lago, E Kozela, E Montero, E Zurita, F Docagne, F Wu, G Disanto, G Musumeci, G Paltser, G Pryce, G Pryce, G Wotherspoon, Gareth Pryce, Gavin Giovannoni, Gregory J. Michael, H Kataoka, HM Vesterinen, I Mendel, J Corey-Bloom, J Karlsson, J Palazuelos, JA Encinas, JB Davis, JH Slingsby, JK O'Neill, JL Croxford, JL Croxford, JM Coquet, JP Zajicek, K Li, K Maresz, KM Spach, L Cristino, LM Olsson, LS Whyte, M Sundvall, M Webb, MF Festing, NA Balenga, NE Buckley, O Ofek, PC Staton, PD Fillmore, PM Hoi, RA Ross, RA Ross, RC Axtell, RG Pertwee, RG Pertwee, RJ Butterfield, Roberto Furlan, RS Graves, Ruth A. Ross, S Al-Izki, S Al-Izki, S Amor, S Amor, S Amor, S Katona, S Levine, S Levine, S Rossi, S Saadoun, Samuel J. Jackson, SC Landis, SJ Allen, Sofia Sisay, V Devonshire, Y Okuda, ZY Lou   +92 more
core   +7 more sources

Cannabinoids, Phenolics, Terpenes and Alkaloids of Cannabis

Molecules, 2021
Cannabis sativa is one of the oldest medicinal plants in the world. It was introduced into western medicine during the early 19th century. It contains a complex mixture of secondary metabolites, including cannabinoids and non-cannabinoid-type ...
Mohamed M. Radwan, Suman Chandra, Shahbaz Gul, Mahmoud A. ElSohly   +3 more
doaj   +1 more source

A Novel CsYABBY3‐CsAS1 Feedback Loop Coordinates Trichome Differentiation and Cannabinoid Biosynthesis in Cannabis sativa L.

Advanced Science, EarlyView.
A novel transcriptional module involving CsYABBY3 and CsAS1 is identified to regulate cannabinoid biosynthesis and trichome development. These factors mutually activate each other and form a protein complex via a conserved residue, acting synergistically to amplify metabolic flux through a coordinate feed‐forward mechanism.
Xuewen Zhu, Yaolei Mi, Xue Cao, Weiqiang Chen, Pucheng Fan, Jing Wang, Yiming Zhang, Wei Yang, Huihua Wan, Shanshan Chen, Xiangxiao Meng, Jun Li, Shuo Shen, Mingkun Huang, Xiaoyu Zhang, Ming Luo, Shilin Chen, Zhichao Xu, Wei Sun   +18 more
wiley   +1 more source

How Cannabinol Is Utilized in Japan, a Country with Strict Cannabis Regulations—Its Purposes, Medical Effects, Adverse Events, and Dependence

Integrative Medicine Reports
Introduction: Cannabinol (CBN) was discovered in 1896, but its commercial use did not take off until recently, and there have been few studies on its use, safety, and efficacy.
Yuji Masataka, Futaba Umemura, Akihiko Nagamine, Naoko Miki, Yoshiyuki Akahoshi, Toshihiko Matsumoto, Ichiro Takumi   +6 more
doaj   +1 more source

Cannabinoids in the Older Person: A Literature Review

Geriatrics, 2020
Introduction: Medical cannabinoids have received significant mainstream media attention in recent times due to an evolving political and clinical landscape.
William Beedham, Magda Sbai, Isabel Allison, Roisin Coary, David Shipway   +4 more
doaj   +1 more source