Results 51 to 60 of about 28,895 (261)

Cannabinoids for epilepsy [PDF]

open access: yesCochrane Database of Systematic Reviews, 2011
Marijuana appears to have anti-epileptic effects in animals. It is not currently known if it is effective in patients with epilepsy. Some states in the United States of America have explicitly approved its use for epilepsy.To assess the efficacy of marijuana, or one of marijuana's constituents in the treatment of people with epilepsy.We searched the ...
David, Gloss, Barbara, Vickrey
openaire   +3 more sources

Micro‐QuEChERS Extraction for Broad‐Spectrum LC‐QQQ‐MS Quantification of Nitazene Analogs in Plasma: A Validated Method With Casework Application

open access: yesDrug Testing and Analysis, EarlyView.
Micro‐QuEChERS sample preparation coupled to LC‐QQQ‐MS enabled sensitive quantification of nitazene analogs in 100 μL of plasma. The validated method provided low detection limits and was successfully applied to an authentic intoxication case involving N‐pyrrolidino protonitazene, supporting clinical and forensic toxicology workflows.
Karla A. O. Souza   +7 more
wiley   +1 more source

Minor Cannabinoids of Cannabis sativa L.

open access: yesJournal of Medical Science, 2019
Cannabinoids from Cannabis sativa L. play an important role as natural products in clinics. The major cannabinoids compromise tetrahydrocannabinolic acid (THCA) and cannabidiolic acid (CBDA) and its decarboxylated analogs.
Fabian Johannes Thomas, Oliver Kayser
doaj   +1 more source

Anticancer properties of cannabidiol and Δ9-tetrahydrocannabinol and synergistic effects with gemcitabine and cisplatin in bladder cancer cell lines

open access: yesJournal of Cannabis Research, 2023
Introduction With the legalization of cannabis in multiple jurisdictions throughout the world, a larger proportion of the population consumes cannabis.
Erin G. Whynot   +2 more
doaj   +1 more source

Progress report on new epilepsy treatments: A summary of the Eighteenth Eilat Conference on New Antiepileptic Drugs and Devices (EILAT XVIII). II. Treatments in more advanced clinical development

open access: yesEpilepsia, EarlyView.
Abstract This article summarizes data for 13 investigational treatments for which at least preliminary seizure outcome data in patients with epilepsy were reported at the Eighteenth Eilat Conference on New Antiepileptic Drugs and Devices held in Madrid, Spain, on May 3–6, 2026.
Meir Bialer   +7 more
wiley   +1 more source

In-depth comparison of the metabolic and pharmacokinetic behaviour of the structurally related synthetic cannabinoids AMB-FUBINACA and AMB-CHMICA in rats

open access: yesCommunications Biology, 2022
Synthetic cannabinoids are amongst the most widely used psychoactive drugs which are tightly controlled by government agencies around the world. Here, pharmacokinetics of two synthetic cannabinoids in rats are evaluated along with their metabolites and ...
David Fabregat-Safont   +8 more
doaj   +1 more source

Cannabinoids and Pain [PDF]

open access: yesPain Research and Management, 2001
Cannabinoids have been used to treat pain for many centuries. However, only during the past several decades have rigorous scientific methods been applied to understand the mechanisms of cannabinoid action. Cannabinoid receptors were discovered in the late 1980s and have been found to mediate the effects of cannabinoids on the nervous system.
J Michael Walker   +2 more
openaire   +3 more sources

Transdiagnostic and symptom‐domain associations between mental illnesses and future self‐connectedness versus future self‐valence

open access: yesJCPP Advances, EarlyView.
Abstract Background Future time perspective dimensions have been linked to various mental illnesses. Given the tendency for mental illnesses to co‐occur, it is necessary to disentangle associations between future‐oriented constructs and shared versus symptom‐domain‐specific psychopathology.
Yi Yang   +6 more
wiley   +1 more source

Cannabinoids and Viral Infections

open access: yesPharmaceuticals, 2010
Exogenous cannabinoids or receptor antagonists may influence many cellular and systemic host responses. The anti-inflammatory activity of cannabinoids may compromise host inflammatory responses to acute viral infections, but may be beneficial in ...
Carol Shoshkes Reiss
doaj   +1 more source

Pharmacogenetics of Cannabinoids [PDF]

open access: yesEuropean Journal of Drug Metabolism and Pharmacokinetics, 2017
Although the application of medical marijuana and cannabinoid drugs is controversial, it is a part of modern-day medicine. The list of diseases in which cannabinoids are promoted as a treatment is constantly expanding. Cases of significant improvement in patients with a very poor prognosis of glioma or epilepsy have already been described. However, the
Hryhorowicz, Szymon   +4 more
openaire   +2 more sources

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