Results 51 to 60 of about 47,203 (289)

Cannabinoids in psychiatry:They are here to stay

, 2022
Cannabinoids are commonly perceived by the public as safe and effective for improving mental health, despite limited evidence to support their use. We discuss reasons why cannabinoids may be particularly compelling for our patients and provide strategies
Bhattacharyya, Sagnik; id_orcid, Woo, Julia Jiyeon, Samaan, Zainab, Van Reekum, Emma, Sagnik Bhattacharyya, Zainab Samaan, Julia Jiyeon Woo, Emma van Reekum   +7 more
core   +1 more source

Targeting Cannabinoid 1 Receptor in Macrophages Alleviates Psoriatic Skin Inflammation Through the AUF1–NLRP3 Axis

Advanced Science, EarlyView.
Macrophage CB1R emerges as a key driver of psoriatic inflammation by suppressing AUF1‐mediated post‐transcriptional control of NLRP3. CB1R inhibition restores AUF1‐dependent NLRP3 mRNA decay, restrains inflammasome activation, and alleviates psoriasis‐like inflammation.
Hongseo Choi, Sukyoung Han, Jinho Kim, Ji Hye Han, Eunsu Kim, Yeonjeong Heo, Minju Lee, Jooyoung Lee, Heerim You, Soyoun Lee, Su‐Hee Han, Ilrok Yoon, Sung Anjeon, Hyerim Kang, Seungyeon Ryu, Hyun‐Ji Park, Eunha Kim, Chul Hwan Bang, Ji Hyun Lee, Josephine M. Egan, Jung‐Woong Kim, Eun Kyung Lee, Wook Kim   +22 more
wiley   +1 more source

Inhibitory Effects of Cannabinoids on Acetylcholinesterase and Butyrylcholinesterase Enzyme Activities

Medical Cannabis and Cannabinoids, 2022
Introduction: Acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) are two cholinergic enzymes catalyzing the reaction of cleaving acetylcholine into acetate and choline at the neuromuscular junction.
Tess Puopolo, Chang Liu, Hang Ma, Navindra P. Seeram   +3 more
doaj   +1 more source

Road Safety: increase in blood concentrations of cannabinoids between 2010 and 2013 – assessment of confirmation tests [PDF]

, 2014
In 2008, the French government decided to set up oral-fluid drug screening in drivers. This new practice modified the customs of police officers and the number of screenings and confirming tests increased dramatically.
Gaillard, Yvan, Bévalot, Fabien, Bouvot, Xavier, Carlin, Michelle, Coste, Damien, Roussel, Olivier   +5 more
core  

Prescription Practices of Cannabinoids in Children with Cerebral Palsy Worldwide—A Survey of the Swiss Cerebral Palsy Registry. [PDF]

, 2023
Cannabinoids are prescribed to children with cerebral palsy despite limited evidence. We aimed to assess cannabinoid prescribing practices in children with cerebral palsy, focusing on indications, types of preparations used, and tolerability ...
Morosoli, Federico, Tscherter, Anne, Hunziker, Sandra, Sandra Hunziker, Anne Tscherter, Grunt, Sebastian, Zuercher, Kathrin, Kathrin Zuercher, Sebastian Grunt, Federico Morosoli   +9 more
core   +2 more sources

Hypothalamic POMC Neurons Gate the Fear‐Feeding Trade‐Off

Advanced Science, EarlyView.
Hungry animals must continually arbitrate between feeding and defensive behaviors when confronted with potential threats. We show that hypothalamic POMC neurons engage CRH‐expressing stress circuits and downstream hormonal responses to coordinate this behavioral selection between competing behaviors.
Cristina Miralpeix, Abel Eraso‐Pichot, Vincent Simon, Victor Jouque, Melissa Sadallah, Samantha Clark, Philippe Zizzari, Urszula Skupio, Ana Covelo, Nathalie Dupuy, Jean Charles Nicolas, Astrid Cannich, Thierry Leste‐Lasserre, Guillaume Laplagne, Carmelo Quarta, Giovanni Marsicano, Daniela Cota   +16 more
wiley   +1 more source

How Cannabinol Is Utilized in Japan, a Country with Strict Cannabis Regulations—Its Purposes, Medical Effects, Adverse Events, and Dependence

Integrative Medicine Reports
Introduction: Cannabinol (CBN) was discovered in 1896, but its commercial use did not take off until recently, and there have been few studies on its use, safety, and efficacy.
Yuji Masataka, Futaba Umemura, Akihiko Nagamine, Naoko Miki, Yoshiyuki Akahoshi, Toshihiko Matsumoto, Ichiro Takumi   +6 more
doaj   +1 more source

Semi-quantitative analysis of cannabinoids in hemp (Cannabis sativa L.) using gas chromatography coupled to mass spectrometry

Journal of Cannabis Research, 2022
Background Hemp (Cannabis sativa L.) is a producer of cannabinoids. These organic compounds are of increasing interest due to their potential applications in the medicinal field.
Luca De Prato, Matthew Timmins, Omid Ansari, Katinka X. Ruthrof, Giles E. St. J. Hardy, John Howieson, Graham O’Hara   +6 more
doaj   +1 more source

Cannabinoids as Key Regulators of Inflammasome Signaling: A Current Perspective

Frontiers in Immunology, 2021
Inflammasomes are cytoplasmic inflammatory signaling protein complexes that detect microbial materials, sterile inflammatory insults, and certain host-derived elements. Inflammasomes, once activated, promote caspase-1–mediated maturation and secretion of
Santosh V. Suryavanshi, Igor Kovalchuk, Olga Kovalchuk   +2 more
doaj   +1 more source

Pricing Dynamics in the US Hemp Market: A Vertical Price Transmission Analysis of the Hemp Value Chain

Agribusiness, EarlyView.
ABSTRACT The US hemp market is a new and nascent industry that has been devoid of research for about half a century. This study examined the effects of exogenous shock on price at each phase of the value chain—Farm (hemp biomass), and its impact on prices at other phases of the value chain—Intermediary Processor (crude cannabidiol hemp) and Final ...
Solomon Odiase, Tyler Mark, Patalee Buddhika Appuhamilage   +2 more
wiley   +1 more source