Results 1 to 10 of about 31,037 (228)

Long-Term Drop-Seizure Response Patterns to Cannabidiol According to Genetic Status in Lennox-Gastaut Syndrome. [PDF]

CNS Neurosci Ther
Cannabidiol was associated with rapid and sustained long‐term reduction of drop seizures in patients with Lennox–Gastaut syndrome over 24 months of follow‐up. Durable treatment responses were observed across genetically heterogeneous patients, with substantial overlap in longitudinal response trajectories regardless of genetic status.
Na JH, Cho HY, Jeon H, Lee H, Lee YM.
europepmc   +2 more sources

Beyond neurons: Impact of cannabidiol on glial cells in ischemic stroke

Neural Regeneration Research
Ischemic stroke triggers a complex cascade of events involving inflammation, oxidative stress, and glial cell dysfunction, all of which contribute to neuronal damage and impaired recovery.
Victória Linden de Rezende, Khiany Mathias, Cinara Ludvig Gonçalves, Rafael Mariano de Bitencourt, Tatiana Barichello, Fabricia Petronilho   +5 more
doaj   +1 more source

Subthreshold Cannabidiol Potentiates Levetiracetam in the Kainic Acid Model of Temporal Lobe Epilepsy: A Pilot Study

Pharmaceuticals
Refractoriness to antiseizure medications is still a major concern in the pharmacotherapy of epilepsy. For this reason, we decided to evaluate the combination of levetiracetam and cannabidiol, administered at a subthreshold dose, to limit the possible ...
Chiara Lucchi, Mattia Marcucci, Kawther Ameen Muhammed Saeed Aledresi, Anna-Maria Costa, Giuseppe Cannazza, Giuseppe Biagini   +5 more
doaj   +1 more source

Кількісний і якісний склад каннабіноїдних сполук та їх співвідношення у сортів конопель Cannabis sativa L.

Фактори експериментальної еволюції організмів, 2016
Aim. With the aim of creating highly productive with the considerable content of cannabinoid the necessity of applying species with the high level of cannabidiol in the selective work emerges.
А. С. Богданова, Л. М. Горшкова   +1 more
doaj  

Cannabidiol in Adults With Lennox-Gastaut Syndrome: Real-World Experience. [PDF]

Eur J Neurol
Aung P, Miller D, Sewell E, Ritter LM, Theochari E, Stavropoulos I, Delamont R, Richardson MP, Winston JS, Nashef L.   +9 more
europepmc   +1 more source

Stiripentol in Dravet syndrome: preventing prolonged seizures, reducing mortality, and improving value in care. [PDF]

Arq Neuropsiquiatr
Valente K, Caraballo R.
europepmc   +1 more source

Effect of Fenfluramine on convulsive seizures and rescue medication usage: A case series of adults within the Lennox-Gastaut syndrome spectrum. [PDF]

Epilepsy Behav Rep
Chilson L, Zaaimi B, Samarasekera S.
europepmc   +1 more source

Cannabidiol suppresses M2-like macrophage polarization via TRPV4/RhoA/ROCK signaling to alleviate hepatic fibrosis. [PDF]

Front Immunol
Zhao P, Liu Y, Wang L, Yuan M, Wang X, He P, Wang Y.   +6 more
europepmc   +1 more source

Safety of cannabidiol isolated from <i>Cannabis sativa</i> L. as a novel food pursuant to Regulation (EU) 2015/2283. [PDF]

EFSA J
EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA), Turck D, Bohn T, Cámara M, Castenmiller J, De Henauw S, Jos Á, Maciuk A, Mangelsdorf I, McNulty B, Naska A, Pentieva K, Siani A, Thies F, Cubadda F, McArdle HJ, Trezza V, Albert O, Beneventi E, Laganaro M, Nuin Garciarena I, Rossi A, Berrío Cruz S, Seminati F, Magani M, Hirsch-Ernst KI.   +26 more
europepmc   +1 more source

Safety of synthetic cannabidiol as a novel food pursuant to regulation (EU) 2015/2283. [PDF]

EFSA J
EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA), Turck D, Bohn T, Cámara M, Castenmiller J, De Henauw S, Jos Á, Maciuk A, Mangelsdorf I, McNulty B, Naska A, Pentieva K, Siani A, Thies F, Cubadda F, McArdle HJ, Trezza V, Albert O, Beneventi E, Laganaro M, Nuin Garciarena I, Rossi A, Cruz SB, Seminati F, Magani M, Hirsch-Ernst KI.   +26 more
europepmc   +1 more source